ID   A0A0N1I635_LEPSE        Unreviewed;       878 AA.
AC   A0A0N1I635;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Spindle pole body component {ECO:0000256|RuleBase:RU363050};
GN   ORFNames=ABL78_2463 {ECO:0000313|EMBL:KPI88450.1};
OS   Leptomonas seymouri.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leptomonas.
OX   NCBI_TaxID=5684 {ECO:0000313|EMBL:KPI88450.1, ECO:0000313|Proteomes:UP000038009};
RN   [1] {ECO:0000313|EMBL:KPI88450.1, ECO:0000313|Proteomes:UP000038009}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 30220 {ECO:0000313|EMBL:KPI88450.1,
RC   ECO:0000313|Proteomes:UP000038009};
RX   PubMed=26317207;
RA   Kraeva N., Butenko A., Hlavacova J., Kostygov A., Myskova J., Grybchuk D.,
RA   Lestinova T., Votypka J., Volf P., Opperdoes F., Flegontov P., Lukes J.,
RA   Yurchenko V.;
RT   "Leptomonas seymouri: Adaptations to the Dixenous Life Cycle Analyzed by
RT   Genome Sequencing, Transcriptome Profiling and Co-infection with Leishmania
RT   donovani.";
RL   PLoS Pathog. 11:E1005127-E1005127(2015).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center {ECO:0000256|RuleBase:RU363050}.
CC   -!- SIMILARITY: Belongs to the TUBGCP family.
CC       {ECO:0000256|ARBA:ARBA00010337, ECO:0000256|RuleBase:RU363050}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPI88450.1}.
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DR   EMBL; LJSK01000050; KPI88450.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N1I635; -.
DR   EnsemblProtists; KPI88450; KPI88450; ABL78_2463.
DR   VEuPathDB; TriTrypDB:Lsey_0050_0210; -.
DR   OMA; GCSFANC; -.
DR   OrthoDB; 1328394at2759; -.
DR   Proteomes; UP000038009; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
DR   GO; GO:0000922; C:spindle pole; IEA:InterPro.
DR   GO; GO:0043015; F:gamma-tubulin binding; IEA:InterPro.
DR   GO; GO:0007020; P:microtubule nucleation; IEA:InterPro.
DR   Gene3D; 1.20.120.1900; Gamma-tubulin complex, C-terminal domain; 1.
DR   InterPro; IPR007259; GCP.
DR   InterPro; IPR040457; GCP_C.
DR   InterPro; IPR042241; GCP_C_sf.
DR   InterPro; IPR041470; GCP_N.
DR   PANTHER; PTHR19302; GAMMA TUBULIN COMPLEX PROTEIN; 1.
DR   PANTHER; PTHR19302:SF13; GAMMA-TUBULIN COMPLEX COMPONENT 2; 1.
DR   Pfam; PF04130; GCP_C_terminal; 1.
DR   Pfam; PF17681; GCP_N_terminal; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|RuleBase:RU363050};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212,
KW   ECO:0000256|RuleBase:RU363050};
KW   Microtubule {ECO:0000256|ARBA:ARBA00022701, ECO:0000256|RuleBase:RU363050}.
FT   DOMAIN          150..533
FT                   /note="Gamma tubulin complex component protein N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF17681"
FT   DOMAIN          539..858
FT                   /note="Gamma tubulin complex component C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04130"
SQ   SEQUENCE   878 AA;  95799 MW;  F835254C6A14CD04 CRC64;
     MSSNAEWTRF LTSLEKRGIR FDQVQLATNR QEVIRAAGIT DALSIAVIET EWQRNVANSG
     AGGSSVFAES TTSTIGFGST SQSNNGLKPS SNANSLAPLL STGGAGGDSI HPYLKAAPPA
     AYLSELPALD NSSQVLKLPE ELQDTVIASE VLSAAVGLGG LFMLYTPNTA TSIEGFSVSP
     LVPPSMRHLC ETVLPVADAF VALRCVEKAE YEGRSLVLMA LGEVVSEINT SYAHQISKLQ
     LWSEGRPMPL MGVVSEVLRV GHHIVRLRQV LPMDLIRTAL ADAAAPMVSS SSSSGLVGPR
     ILNHLCDQVN RFSGSREDHE LLMLLLRRSL VPYLRMLHRW MHTGVLDDPY EEFFISEVYR
     PSRPAPTAAN QLQQRHVGQF FLDALVPSMA GGGYGGTPDG VGGNLSSSGG SGAAAAGTHG
     RYGTSRRVAA QQDVVSFDRR FSLNKSLVPV FLTAPSKIAK MIFFAGKYCC LLREYGATLP
     PFGASAASGG VSGDGAGATD SGFLLTWSGA DQLQRQVQES FEVASGAVIQ LLFSPSIDLL
     GHLKSLKMYF LQERGDWVVD FLDSADSLLV EYPDRVKAHS MQVLMQAAIA RSCASDPYHD
     LIGCTFADCT LEELLQEQHR SRDSGRELVR IDEGHMGALP TRRSTGGGNG NNDAGGEVDA
     YRSLELLQLE VDLQWPLTLV LDAKVIQRLN IIFRLLIWIK TCERRLCELW YANEILGEFS
     AAYGLKHQFV QFLRQFQFYA AHFVLEPLWS RLITRIGQTD SVFAITQALI DFFDGVETGL
     VLSSTQRFRS LAHILELTER FCEIGMHSST ATMPLIEATL HSVEDQFLRA LSELASPVGP
     DYPQLVPLLT WIDFSRFYDQ NNVYHVQHSS TGAPSRNA
//