ID A0A0N4T2X1_BRUPA Unreviewed; 734 AA.
AC A0A0N4T2X1;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Kin of IRRE-like protein 1 {ECO:0000313|WBParaSite:BPAG_0000255101-mRNA-1};
GN ORFNames=BPAG_LOCUS2521 {ECO:0000313|EMBL:VDN83707.1};
OS Brugia pahangi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6280 {ECO:0000313|Proteomes:UP000038020, ECO:0000313|WBParaSite:BPAG_0000255101-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BPAG_0000255101-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN83707.1, ECO:0000313|Proteomes:UP000278627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; UZAD01000389; VDN83707.1; -; Genomic_DNA.
DR STRING; 6280.A0A0N4T2X1; -.
DR WBParaSite; BPAG_0000255101-mRNA-1; BPAG_0000255101-mRNA-1; BPAG_0000255101.
DR Proteomes; UP000038020; Unplaced.
DR Proteomes; UP000278627; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11640:SF153; IRREGULAR CHIASM C-ROUGHEST PROTEIN-RELATED; 1.
DR PANTHER; PTHR11640; NEPHRIN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13927; Ig_3; 3.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000278627};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 542..563
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..112
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 256..341
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 346..412
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 431..526
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 734 AA; 82655 MW; EDAB593B8AA0ED41 CRC64;
MKWSTTCIII AVSTYIHSEQ RIIEGPADTR ALIGSTAVLK CRIEAQQGAV QWMKNGFGLG
NDRDLSLFKR YSMEGRISKG EYNLRIINVQ MDDDDEYACQ IEAANENPTR VSNLAKLTVL
VKPEDPKLLS PVSNLRTVVG EYIQRSCISK HGKPQAKIGW LISDDPNASS VSLWLGDSRE
KFNPVFKFTN SGQEIQNARV VEYVSSNDDR TYNVISNISF VPRMEDDDKY LVCLVNHETY
ITPQLHAVRL DLNYPPRVEV ELDNNSKLYE HGSAQLFCNV KAKPFKNIKI AWYRNGKEII
LATASTLSIS ELRIDHHQSE YTCVARNVIG DASDSIILNI TFVDGAYIMS RQQHQAVNPG
ETASFICEAI GNPAPTIYWT KVADSQILAR GNNLTIESVQ SWQRGEYECV ATVQGFPPAR
LVNYLHIRGP PSVSLSDEIV AAVGESLEII CEVRGRPQPQ DVLWSLNGVT FEYGRLSSRF
QIHQVARQFG VESRLAIQNI KDSDFGTYNC SAYNELGRDY QTVQLKSKNI VDAFIGLVPP
QYFFPVAFLL FSALFIMGCC SCWQYRRNSY KTAQFSDDRS DVSVKIETLI GNQFFTDMYN
STSNESHQLL CSEDYITMPQ SNPNCYYLSC SPIVNRSIYK TCASHSFDCG TDEQNEQHIS
HPYNSFASSS STAAVTISEP CHYQNSKRRC NIQGYEVLEI KSKVSTPDVK CATLLHNSAV
RMQERLINQI STHT
//
