ID A0A0N4U6T3_DRAME Unreviewed; 499 AA.
AC A0A0N4U6T3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=IPT/TIG domain-containing protein {ECO:0000313|WBParaSite:DME_0000265301-mRNA-1};
GN ORFNames=DME_LOCUS7013 {ECO:0000313|EMBL:VDN57040.1};
OS Dracunculus medinensis (Guinea worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Dracunculoidea; Dracunculidae; Dracunculus.
OX NCBI_TaxID=318479 {ECO:0000313|Proteomes:UP000038040, ECO:0000313|WBParaSite:DME_0000265301-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:DME_0000265301-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN57040.1, ECO:0000313|Proteomes:UP000274756}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU004489}.
CC -!- SIMILARITY: Belongs to the COE family. {ECO:0000256|ARBA:ARBA00010340,
CC ECO:0000256|RuleBase:RU004489}.
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DR EMBL; UYYG01001158; VDN57040.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4U6T3; -.
DR STRING; 318479.A0A0N4U6T3; -.
DR WBParaSite; DME_0000265301-mRNA-1; DME_0000265301-mRNA-1; DME_0000265301.
DR Proteomes; UP000038040; Unplaced.
DR Proteomes; UP000274756; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd11606; COE_DBD; 1.
DR Gene3D; 1.10.287.4280; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.40.3180; Transcription factor COE1, DNA-binding domain; 1.
DR InterPro; IPR032200; COE_DBD.
DR InterPro; IPR038173; COE_DBD_sf.
DR InterPro; IPR032201; COE_HLH.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR003523; Transcription_factor_COE.
DR InterPro; IPR018350; Transcription_factor_COE_CS.
DR PANTHER; PTHR10747; TRANSCRIPTION FACTOR COE FAMILY MEMBER; 1.
DR PANTHER; PTHR10747:SF38; TRANSCRIPTION FACTOR COLLIER; 1.
DR Pfam; PF16422; COE1_DBD; 1.
DR Pfam; PF16423; COE1_HLH; 1.
DR Pfam; PF01833; TIG; 1.
DR SMART; SM00429; IPT; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR PROSITE; PS01345; COE; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|RuleBase:RU004489};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004489};
KW Metal-binding {ECO:0000256|RuleBase:RU004489};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004489};
KW Reference proteome {ECO:0000313|Proteomes:UP000274756};
KW Transcription {ECO:0000256|RuleBase:RU004489};
KW Transcription regulation {ECO:0000256|RuleBase:RU004489};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004489};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004489}.
FT DOMAIN 285..372
FT /note="IPT/TIG"
FT /evidence="ECO:0000259|SMART:SM00429"
SQ SEQUENCE 499 AA; 55985 MW; 3F2A6851246E30BE CRC64;
MFGFQDANLL RQMKEEPLGL RAHWATTVLD TSPARTTNFI ILVANCDVFI LQLSCSIKLI
LRISFFISQL ARAHFEKHPP NNLRKSNFFH FVIALYDRAG QPVEIERTQF TDFIEKEREV
DGQDTRNGIH YKLWLSFANG IRTEQDLYVR LIDSVSKQAI AYEGQDKNPE MCRVLLTHEV
MCSRCCEKKS CGNRNETPSD PVIIDRFFLK FFLKCNQNCL KNAGNPRDMR RFQVVLGVTA
RVDGPLLAIS DNMFVHNNSK HGRRIKRIDP SEDISDSSDI TSATNPVIKA ICPSEGWTQG
GTSVIIIGEN FFEGLQVSFG PTTVWNESIQ VITPHAMRVA TPPRHMPGVV EVTLTYKSKQ
LNRGNPGRFA YISLSEPSID FGFQRLQKLL PKYPGDPERL PKELILKRAA ELAEALYNSQ
QFALPPPRTP ADHLSHYASA YSAQFDTNAD YTRSHTSPRA LSTYGSGTTP HSLSSAVYQG
TYSSVSASPA AQFLNGPSS
//
