ID A0A0N4VRE3_ENTVE Unreviewed; 208 AA.
AC A0A0N4VRE3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Neur_chan_memb domain-containing protein {ECO:0000313|WBParaSite:EVEC_0001361101-mRNA-1};
GN ORFNames=EVEC_LOCUS12739 {ECO:0000313|EMBL:VDD97988.1};
OS Enterobius vermicularis (Human pinworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Enterobius.
OX NCBI_TaxID=51028 {ECO:0000313|Proteomes:UP000038041, ECO:0000313|WBParaSite:EVEC_0001361101-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:EVEC_0001361101-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDD97988.1, ECO:0000313|Proteomes:UP000274131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UXUI01016476; VDD97988.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4VRE3; -.
DR STRING; 51028.A0A0N4VRE3; -.
DR WBParaSite; EVEC_0001361101-mRNA-1; EVEC_0001361101-mRNA-1; EVEC_0001361101.
DR Proteomes; UP000038041; Unplaced.
DR Proteomes; UP000274131; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005230; F:extracellular ligand-gated monoatomic ion channel activity; IEA:UniProt.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR CDD; cd19049; LGIC_TM_anion; 1.
DR Gene3D; 1.20.58.390; Neurotransmitter-gated ion-channel transmembrane domain; 1.
DR InterPro; IPR006028; GABAA/Glycine_rcpt.
DR InterPro; IPR006201; Neur_channel.
DR InterPro; IPR036719; Neuro-gated_channel_TM_sf.
DR InterPro; IPR038050; Neuro_actylchol_rec.
DR InterPro; IPR006029; Neurotrans-gated_channel_TM.
DR PANTHER; PTHR18945:SF538; GLYCINE RECEPTOR SUBUNIT BETA-TYPE 4; 1.
DR PANTHER; PTHR18945; NEUROTRANSMITTER GATED ION CHANNEL; 1.
DR Pfam; PF02932; Neur_chan_memb; 1.
DR PRINTS; PR00253; GABAARECEPTR.
DR SUPFAM; SSF90112; Neurotransmitter-gated ion-channel transmembrane pore; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000274131};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 91..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 91..198
FT /note="Neurotransmitter-gated ion-channel transmembrane"
FT /evidence="ECO:0000259|Pfam:PF02932"
SQ SEQUENCE 208 AA; 23498 MW; CFF5A19414254923 CRC64;
TNTRSYGFSA VSGFVYLVNY FGNAYDVEQL KVEWNEPNSI GINEDIMMPD MRLKEIKPTL
KNTTYVTGIW SCAIAQFVVD REIMHHLLQS YLPTALIVVI SWFGFWLDVE SVPGRVSLSI
TTLLTLATQS SAARMALPQA SYVKAIDVWI GTCMAFAFAA MIEFTVVSYC LRVKWKQKDK
GFVALFQQMF LSPSPQVWSA YQNNASKN
//
