ID   A0A0N4WGV8_HAEPC        Unreviewed;       720 AA.
AC   A0A0N4WGV8;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Integrase catalytic domain-containing protein {ECO:0000313|WBParaSite:HPLM_0001007501-mRNA-1};
OS   Haemonchus placei (Barber's pole worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX   NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0001007501-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:HPLM_0001007501-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   AlphaFoldDB; A0A0N4WGV8; -.
DR   WBParaSite; HPLM_0001007501-mRNA-1; HPLM_0001007501-mRNA-1; HPLM_0001007501.
DR   OMA; RTYIRAN; -.
DR   Proteomes; UP000038042; Unplaced.
DR   GO; GO:0042575; C:DNA polymerase complex; IEA:UniProt.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 1.10.340.70; -; 1.
DR   Gene3D; 3.10.20.370; -; 1.
DR   Gene3D; 3.30.70.270; -; 2.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR041588; Integrase_H2C2.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041373; RT_RNaseH.
DR   PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR   Pfam; PF17921; Integrase_H2C2; 1.
DR   Pfam; PF17917; RT_RNaseH; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   4: Predicted;
FT   DOMAIN          561..720
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
SQ   SEQUENCE   720 AA;  81354 MW;  068F29D5A88ECC4C CRC64;
     MAAQYGVSQK KDGSLRVCLD FRPLNKITIP DRYPLPRIED LLERVAGKRF YTSFDLASGY
     MQLLLSPESQ AKCGWATHRG VNQFVYLPFS SRNAGAYFCR AMSRTLAGLD DNCLAYLDDI
     IVFDNDFDTH LCSLRKVLDR FRTFNIKVSG KKLTSIAQSK ITFLGHEISG SLYSPAERNL
     SAIRNLPAPT SVQSKASWVW STSFVNSRRT LLAAPFYALC KDKTSFKWDT PQATAFARLK
     EVLTSRPCSA FPQDKKFILH TDGSKVAVGA ALLQQQDPDL LPKVIGYFSK TLSPSQQKWS
     PTYIELFAMI SALRFFRATI YGNHTRVLCD HQPLPFLLRH RKPQDHMARW VVKLQSFDIT
     IEYQKGSSNV LADHLSRNSD PTNHFTDGTS ESEDIVEFPR CLLQRIEQPH APRSATEPPL
     TPPLFVRPYD ALLAQKEDPL CSAIMHFLET GSFPDRTPPE IQDTARDLAD RCLLKNNGCL
     YFVDPLRSPS SAAIFVPTKL REPICVALYD SPTAGGHFGW KKTLAKITRR FFWPTLKEDV
     YRFVCSCKAC QRKRPHPTAR EILIPIHAGA IFDKVYLDLS GPYHPTPRHN KYIICLIDHF
     SRFVIAAPLP DCTAVTVAHA IMNHCILVFG AMTTLITDNA SYFKGDLLTE LGRLLLIGRY
     FTTPYHHEGN GVCERVFATF QEMLRTYIRA NQSDKDLFYQ RAYSPTILLS MAAPASLPSS
//