ID   A0A0N4WJ89_HAEPC        Unreviewed;       237 AA.
AC   A0A0N4WJ89;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Peptidase A1 domain-containing protein {ECO:0000313|WBParaSite:HPLM_0001106801-mRNA-1};
GN   ORFNames=HPLM_LOCUS11060 {ECO:0000313|EMBL:VDO41887.1};
OS   Haemonchus placei (Barber's pole worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX   NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0001106801-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:HPLM_0001106801-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO41887.1, ECO:0000313|Proteomes:UP000268014}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHpl1 {ECO:0000313|EMBL:VDO41887.1,
RC   ECO:0000313|Proteomes:UP000268014};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase A1 family.
CC       {ECO:0000256|ARBA:ARBA00007447}.
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DR   EMBL; UZAF01017461; VDO41887.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N4WJ89; -.
DR   STRING; 6290.A0A0N4WJ89; -.
DR   WBParaSite; HPLM_0001106801-mRNA-1; HPLM_0001106801-mRNA-1; HPLM_0001106801.
DR   OMA; LFTIWID; -.
DR   Proteomes; UP000038042; Unplaced.
DR   Proteomes; UP000268014; Unassembled WGS sequence.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd05471; pepsin_like; 1.
DR   Gene3D; 2.40.70.10; Acid Proteases; 1.
DR   InterPro; IPR001461; Aspartic_peptidase_A1.
DR   InterPro; IPR034164; Pepsin-like_dom.
DR   InterPro; IPR033121; PEPTIDASE_A1.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   PANTHER; PTHR47966:SF8; ASPARTIC PROTEASE 1-RELATED; 1.
DR   PANTHER; PTHR47966; BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED; 1.
DR   Pfam; PF00026; Asp; 1.
DR   PRINTS; PR00792; PEPSIN.
DR   SUPFAM; SSF50630; Acid proteases; 1.
DR   PROSITE; PS51767; PEPTIDASE_A1; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000268014}.
FT   DOMAIN          1..230
FT                   /note="Peptidase A1"
FT                   /evidence="ECO:0000259|PROSITE:PS51767"
SQ   SEQUENCE   237 AA;  25748 MW;  011FD43797B0B5B0 CRC64;
     PKQEFGVATT LAEVFGYQPV DGILGLGWPA LAVDKVVPPM QNLLSSLDQP LFTVWMDRKL
     TVSNGGNAGL ITYGAIDTKN CQSQINYVPL SAETYWQFPI DGFAIGSYSE TKKEQVISDT
     GTSWIGAPTT VVSAVVKQTG AKYDFLNELY TVDCSTQKTQ PDLIFTINGI KYNVPSVEYV
     LDLGLGNGKC ALTFFGMNSG GFGPAWILGD TWIRTYCNIY DIGQKRIGFA KANHSGL
//