ID A0A0N4XJM4_NIPBR Unreviewed; 310 AA.
AC A0A0N4XJM4;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=ATP citrate synthase {ECO:0000256|ARBA:ARBA00012639};
DE EC=2.3.3.8 {ECO:0000256|ARBA:ARBA00012639};
GN ORFNames=NBR_LOCUS2727 {ECO:0000313|EMBL:VDL66316.1};
OS Nippostrongylus brasiliensis (Rat hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Heligmosomidae; Nippostrongylus.
OX NCBI_TaxID=27835 {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0000272601-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:NBR_0000272601-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDL66316.1, ECO:0000313|Proteomes:UP000271162}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYSL01003390; VDL66316.1; -; Genomic_DNA.
DR STRING; 27835.A0A0N4XJM4; -.
DR WBParaSite; NBR_0000272601-mRNA-1; NBR_0000272601-mRNA-1; NBR_0000272601.
DR OMA; IHNARYK; -.
DR Proteomes; UP000038043; Unplaced.
DR Proteomes; UP000271162; Unassembled WGS sequence.
DR GO; GO:0003878; F:ATP citrate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 1.
DR InterPro; IPR032263; Citrate-bd.
DR InterPro; IPR002020; Citrate_synthase.
DR InterPro; IPR003781; CoA-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR016102; Succinyl-CoA_synth-like.
DR PANTHER; PTHR23118; ATP-CITRATE SYNTHASE; 1.
DR PANTHER; PTHR23118:SF42; ATP-CITRATE SYNTHASE; 1.
DR Pfam; PF16114; Citrate_bind; 1.
DR Pfam; PF02629; CoA_binding; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000271162};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..144
FT /note="ATP-citrate synthase citrate-binding"
FT /evidence="ECO:0000259|Pfam:PF16114"
FT DOMAIN 192..297
FT /note="CoA-binding"
FT /evidence="ECO:0000259|Pfam:PF02629"
SQ SEQUENCE 310 AA; 34191 MW; AC64AD74ACFBE7AE CRC64;
MVAGGGASVV FTDTVCDLGG ASELANYGEY SGDPSETQTF EYAKTLLSVM TEGPPDPRGK
VLIIGGSIAN FTNVAKTFNG IVRAFETFVD RVREHKVTVF VRRGGPNYQE GLRRIKDAAQ
KLELPIHVFG PETHMTAIVG AALGIHDLPA VPHVPQTTGQ FLLSPERNVS FVLIHNARYK
QAHKLYESLF ENDTKAIVWG QQQKAIQGML DFDYVCRRAE PSVVASTYPF TGDNKQKYYF
GHREILIPAY KSMAKAFATH PDATVLVTFA SLRSVYETVL QALQFPQIRV IAIIAEGVPE
NQTRKLIKVS
//
