ID A0A0N4Y366_NIPBR Unreviewed; 433 AA.
AC A0A0N4Y366;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=WW domain-binding protein 4 (inferred by orthology to a human protein) {ECO:0000313|WBParaSite:NBR_0001022501-mRNA-1};
GN ORFNames=NBR_LOCUS10226 {ECO:0000313|EMBL:VDL73815.1};
OS Nippostrongylus brasiliensis (Rat hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Heligmosomidae; Nippostrongylus.
OX NCBI_TaxID=27835 {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0001022501-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:NBR_0001022501-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDL73815.1, ECO:0000313|Proteomes:UP000271162}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYSL01020276; VDL73815.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4Y366; -.
DR STRING; 27835.A0A0N4Y366; -.
DR WBParaSite; NBR_0001022501-mRNA-1; NBR_0001022501-mRNA-1; NBR_0001022501.
DR OMA; EICKVWF; -.
DR Proteomes; UP000038043; Unplaced.
DR Proteomes; UP000271162; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR InterPro; IPR000690; Matrin/U1-C_Znf_C2H2.
DR InterPro; IPR003604; Matrin/U1-like-C_Znf_C2H2.
DR InterPro; IPR013085; U1-CZ_Znf_C2H2.
DR InterPro; IPR040023; WBP4.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR13173; WW DOMAIN BINDING PROTEIN 4; 1.
DR PANTHER; PTHR13173:SF10; WW DOMAIN-BINDING PROTEIN 4; 1.
DR Pfam; PF06220; zf-U1; 1.
DR SMART; SM00456; WW; 1.
DR SMART; SM00451; ZnF_U1; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
DR PROSITE; PS50171; ZF_MATRIN; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000271162};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 11..42
FT /note="Matrin-type"
FT /evidence="ECO:0000259|PROSITE:PS50171"
FT DOMAIN 170..203
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT REGION 325..395
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 373..395
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 433 AA; 47919 MW; 4F474AD23055B9DC CRC64;
MADVWKSQDR KFCTICKVWF GDNRASIEFH ERGRKHKDAL AAKLRELGRA SKEKEREQSK
MSSALAAMEA AALKSMREHG EALEQGPALP STGLASRIFD PRQMKDVGLM AREMAKRKNE
MKELHNQKRS SAAAPPVAKY FKRDLHTTID YSEFTAPIVK EEQEPVAASS SAQGFWVEAD
AGDGRNYYFH MYTGESTWDR PESFLTAEQY GMYLQSTGAA LKTEIPDVKE EECSSHPSEL
PVENTAVEEA SGSVAVKSEP CDDDMIDFSS EIADIPLPET DYVQPTVSDM VPKEALSPVA
VEPLEAHDSG KVTTLPVMPS HNSACGAETF SGTAHEAEAE EEEGTASSTG PFGSWTRVKK
TDNAPVFSPL TAKYRADEER ERKAAEEREK QAAKAEPVIE FTEKTSAVLT KKVKGPIEFK
KKTAVKNVRQ RVQ
//
