ID   A0A0N4YCI1_NIPBR        Unreviewed;       590 AA.
AC   A0A0N4YCI1;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=RING-type domain-containing protein {ECO:0000313|WBParaSite:NBR_0001424901-mRNA-1};
GN   ORFNames=NBR_LOCUS14250 {ECO:0000313|EMBL:VDL77839.1};
OS   Nippostrongylus brasiliensis (Rat hookworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Heligmosomidae; Nippostrongylus.
OX   NCBI_TaxID=27835 {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0001424901-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:NBR_0001424901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDL77839.1, ECO:0000313|Proteomes:UP000271162}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UYSL01021291; VDL77839.1; -; Genomic_DNA.
DR   STRING; 27835.A0A0N4YCI1; -.
DR   WBParaSite; NBR_0001424901-mRNA-1; NBR_0001424901-mRNA-1; NBR_0001424901.
DR   OMA; ALRCSHI; -.
DR   Proteomes; UP000038043; Unplaced.
DR   Proteomes; UP000271162; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0045202; C:synapse; IEA:GOC.
DR   GO; GO:0033130; F:acetylcholine receptor binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043495; F:protein-membrane adaptor activity; IEA:InterPro.
DR   GO; GO:0007268; P:chemical synaptic transmission; IEA:InterPro.
DR   CDD; cd16478; RING-H2_Rapsyn; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR019568; Rapsyn_myristoylation/link_N.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR001965; Znf_PHD.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR46574; 43 KDA RECEPTOR-ASSOCIATED PROTEIN OF THE SYNAPSE; 1.
DR   PANTHER; PTHR46574:SF1; 43 KDA RECEPTOR-ASSOCIATED PROTEIN OF THE SYNAPSE; 1.
DR   Pfam; PF10579; Rapsyn_N; 1.
DR   Pfam; PF13639; zf-RING_2; 1.
DR   SMART; SM00249; PHD; 1.
DR   SMART; SM00184; RING; 1.
DR   SMART; SM00028; TPR; 5.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000271162};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          405..449
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REGION          498..590
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        509..535
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        558..572
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   590 AA;  66567 MW;  1A41474366EB5C74 CRC64;
     MGAESGVLRP PHYFFNTLAP SRSFPPAQLW TQVVGHVDFP TQAGVRLYHQ RHHAQAIHKW
     RQALNRLTNA EDRFITLGYL AQAFCDSGEF EAMLHYALQQ MELANERHDE YMKSEAFLNL
     AKAYERLADF SKALSYGKAS LQHPSMDPRT PGYAHLAIAY AHLGFSQFQN CLEAFEQAMN
     VANETGDKLL ELQICVGLGS LFTLLRDLTK ALIFLRNAMA IIQSVTVDDV HTKYRCTILY
     HLSVALRMRG SLVEAKEACD EAIQLATETG NRALHARCMC SLADIYRELG ESEAKETLTK
     SWARYEEAYR VLRASQDRMG EVLVLASMAK SASESRSHYT GQCECQAIQL NKKCLDIART
     LGCKHVMLKC HSRLAELYSQ LNDEDSEEVA RRAASQLTQE MELFCNFCGQ RYGMKDESLQ
     ALRCSHVFHE RCLHTFLLER EDQTCPKCRC RAILSDNISM RTPSICSTVD AHMPSTSQLP
     SALSGAVRTP LIAAAEELGN TRPQSTLTRA RQAERDIDRV DRALNRMENK NDTNVLKKSR
     PPPPPRKPCC SKDGLPPSSS SDHHRRLEAD HLLPHQSAVY SSTRADRDFH
//