ID   A0A0N4YE81_NIPBR        Unreviewed;       275 AA.
AC   A0A0N4YE81;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Sphingomyelin synthase-related 2 (inferred by orthology to a C. elegans protein) {ECO:0000313|WBParaSite:NBR_0001498101-mRNA-1};
GN   ORFNames=NBR_LOCUS14982 {ECO:0000313|EMBL:VDL78576.1};
OS   Nippostrongylus brasiliensis (Rat hookworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Heligmosomidae; Nippostrongylus.
OX   NCBI_TaxID=27835 {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0001498101-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:NBR_0001498101-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDL78576.1, ECO:0000313|Proteomes:UP000271162}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the sphingomyelin synthase family.
CC       {ECO:0000256|ARBA:ARBA00005441}.
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DR   EMBL; UYSL01021559; VDL78576.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N4YE81; -.
DR   STRING; 27835.A0A0N4YE81; -.
DR   WBParaSite; NBR_0001498101-mRNA-1; NBR_0001498101-mRNA-1; NBR_0001498101.
DR   OMA; VALAWIH; -.
DR   Proteomes; UP000038043; Unplaced.
DR   Proteomes; UP000271162; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups; IEA:InterPro.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR045221; Sphingomyelin_synth-like.
DR   InterPro; IPR025749; Sphingomyelin_synth-like_dom.
DR   PANTHER; PTHR21290:SF4; SPHINGOMYELIN SYNTHASE-RELATED 2; 1.
DR   PANTHER; PTHR21290; SPHINGOMYELIN SYNTHETASE; 1.
DR   Pfam; PF14360; PAP2_C; 1.
PE   3: Inferred from homology;
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00022919};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000271162};
KW   Sphingolipid metabolism {ECO:0000256|ARBA:ARBA00022919};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        26..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        84..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        149..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          146..178
FT                   /note="Sphingomyelin synthase-like"
FT                   /evidence="ECO:0000259|Pfam:PF14360"
SQ   SEQUENCE   275 AA;  32223 MW;  1051B9317732F19D CRC64;
     MIDKEKREIL PTSITKSYVV RRLPTVFAMG FVGLGWTLNE VALAWIHERV PRDTKPLPDL
     WFSWFPEVVP LTEFIYRWVV SRRVLFCAAL AYCFRALCIT IFQVPVPSVH TYCAPKTNGS
     LYIVSARVAR MFWSAGIEQL RPRELCGDLI VSGHTLTIFT SFYTFKYYAP KKLKVIRSSG
     SFSHQLVPGR RFKIFKSLFI NNTFSSYTVS TRVFMEYHAL MVSYHEHSLE KNILSWSWWA
     RIVPYFEKDA PPPHAFHNRI EWPSSCPQRI RRRLV
//