ID A0A0N4YIW7_NIPBR Unreviewed; 313 AA.
AC A0A0N4YIW7;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Kunitz/Bovine pancreatic trypsin inhibitor domain protein {ECO:0000313|WBParaSite:NBR_0001687401-mRNA-1};
GN ORFNames=NBR_LOCUS16875 {ECO:0000313|EMBL:VDL80470.1};
OS Nippostrongylus brasiliensis (Rat hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Heligmosomidae; Nippostrongylus.
OX NCBI_TaxID=27835 {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0001687401-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:NBR_0001687401-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDL80470.1, ECO:0000313|Proteomes:UP000271162}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00500}.
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DR EMBL; UYSL01022438; VDL80470.1; -; Genomic_DNA.
DR STRING; 27835.A0A0N4YIW7; -.
DR WBParaSite; NBR_0001687401-mRNA-1; NBR_0001687401-mRNA-1; NBR_0001687401.
DR OMA; WFDVETF; -.
DR Proteomes; UP000038043; Unplaced.
DR Proteomes; UP000271162; Unassembled WGS sequence.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd00109; Kunitz-type; 1.
DR CDD; cd00191; TY; 1.
DR Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 1.
DR Gene3D; 4.10.800.10; Thyroglobulin type-1; 2.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR InterPro; IPR020901; Prtase_inh_Kunz-CS.
DR InterPro; IPR000716; Thyroglobulin_1.
DR InterPro; IPR036857; Thyroglobulin_1_sf.
DR PANTHER; PTHR47248; PROTEIN CBG06772; 1.
DR PANTHER; PTHR47248:SF7; PROTEIN CBG19214; 1.
DR Pfam; PF00014; Kunitz_BPTI; 1.
DR Pfam; PF00086; Thyroglobulin_1; 2.
DR SMART; SM00131; KU; 1.
DR SMART; SM00211; TY; 2.
DR SUPFAM; SSF57362; BPTI-like; 1.
DR SUPFAM; SSF57610; Thyroglobulin type-1 domain; 2.
DR PROSITE; PS00280; BPTI_KUNITZ_1; 1.
DR PROSITE; PS50279; BPTI_KUNITZ_2; 1.
DR PROSITE; PS00484; THYROGLOBULIN_1_1; 1.
DR PROSITE; PS51162; THYROGLOBULIN_1_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00500}; Reference proteome {ECO:0000313|Proteomes:UP000271162};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..313
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041040199"
FT DOMAIN 86..156
FT /note="Thyroglobulin type-1"
FT /evidence="ECO:0000259|PROSITE:PS51162"
FT DOMAIN 189..242
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DISULFID 123..130
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00500"
SQ SEQUENCE 313 AA; 34068 MW; A015699D3AE57C64 CRC64;
MLALVIASFA VLCHAVSVPL SNARSGTAAL PQAGPCTQNN DGMKCTKHGY YDTIQCDSRG
CFCVNAHNGI IAFDTKTSSN RTMPRCSGCH NSIKKMVGEG SITDGTFVPK CDAILGNFEP
LQCDLKRKVC YCVDVQTGTE IANTRKSMAA KKSITCDGTE FSIDPEQFPS PVQSTMTADM
RYPVAKETCR LDRSKGNTCR GAKPSTRYFF DHTTFSCLSF EYLGCGGNDN NYKTSSDCYS
NCMLREFLTG GASYTKISDR FDAAYHPKCS NGRSAYAIDM GGWNSTVLGK SCKDNFCPPG
YKCQDGDIFA YCC
//
