ID A0A0N4YRK2_NIPBR Unreviewed; 440 AA.
AC A0A0N4YRK2;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Probable histone-lysine N-methyltransferase lin-59 (inferred by orthology to a C. elegans protein) {ECO:0000313|WBParaSite:NBR_0001987401-mRNA-1};
GN ORFNames=NBR_LOCUS19875 {ECO:0000313|EMBL:VDL83611.1};
OS Nippostrongylus brasiliensis (Rat hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Heligmosomidae; Nippostrongylus.
OX NCBI_TaxID=27835 {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0001987401-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:NBR_0001987401-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDL83611.1, ECO:0000313|Proteomes:UP000271162}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; UYSL01024579; VDL83611.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4YRK2; -.
DR STRING; 27835.A0A0N4YRK2; -.
DR WBParaSite; NBR_0001987401-mRNA-1; NBR_0001987401-mRNA-1; NBR_0001987401.
DR OMA; VWCIGRP; -.
DR Proteomes; UP000038043; Unplaced.
DR Proteomes; UP000271162; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 2.30.30.490; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001025; BAH_dom.
DR InterPro; IPR043151; BAH_sf.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46147; HISTONE-LYSINE N-METHYLTRANSFERASE ASH1; 1.
DR PANTHER; PTHR46147:SF3; HISTONE-LYSINE N-METHYLTRANSFERASE ASH1; 1.
DR Pfam; PF01426; BAH; 1.
DR Pfam; PF20826; PHD_5; 1.
DR SMART; SM00439; BAH; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS51038; BAH; 1.
DR PROSITE; PS50868; POST_SET; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000271162};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT TRANSMEM 393..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..23
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
FT DOMAIN 239..366
FT /note="BAH"
FT /evidence="ECO:0000259|PROSITE:PS51038"
SQ SEQUENCE 440 AA; 50716 MW; 380E85A1EFBA0297 CRC64;
MSGLLPVSRD CKCGSSDCRK RVVMARNPPI ACANDLSINE EQVVREHNLF LVRNRQHCIA
RAASHGLVGS FGPPLSQLDG MQTVLKGIVY RNKSRMLQVG GYDPDQAWPL GKANEKDDAV
RCICGSLEED GEMTQCDTCN FWLHSECLRD VDHDSEYKCQ FCRGVISGGR PCSDVILAKQ
PDIRLHSCSY YKALTNNRSI QVRLNETVHV LKTIKDDHKK ILKKLMDVSE KNEKKKNDKE
EEKFDDIPLA PENRLPHETF HRKDLRVFRV ERLFAAPGGH RFVFGFYYAR PHETFCDSQR
IFHRNEVFST PLYDTLPLDA VVGRCAVLDA SVWCIGRPTV PSFKEEDVYI CEYQIDRNQR
SFEKIPSKNR YPINTQPYVF KKFKEAITIK RDFTAFLIFY FFLIFCFSSS PGTFISAVHC
RSVRFLVVVQ TVDENRERIE
//
