ID   A0A0N4ZC00_PARTI        Unreviewed;       415 AA.
AC   A0A0N4ZC00;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Peptidase A1 domain-containing protein {ECO:0000313|WBParaSite:PTRK_0000505500.1};
OS   Parastrongyloides trichosuri (Possum-specific nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Parastrongyloides.
OX   NCBI_TaxID=131310 {ECO:0000313|Proteomes:UP000038045, ECO:0000313|WBParaSite:PTRK_0000505500.1};
RN   [1] {ECO:0000313|WBParaSite:PTRK_0000505500.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the peptidase A1 family.
CC       {ECO:0000256|ARBA:ARBA00007447}.
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DR   AlphaFoldDB; A0A0N4ZC00; -.
DR   STRING; 131310.A0A0N4ZC00; -.
DR   WBParaSite; PTRK_0000505500.1; PTRK_0000505500.1; PTRK_0000505500.
DR   Proteomes; UP000038045; Unplaced.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd05471; pepsin_like; 1.
DR   Gene3D; 2.40.70.10; Acid Proteases; 3.
DR   InterPro; IPR001461; Aspartic_peptidase_A1.
DR   InterPro; IPR034164; Pepsin-like_dom.
DR   InterPro; IPR033121; PEPTIDASE_A1.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   PANTHER; PTHR47966:SF45; ASPARTIC PROTEASE 6; 1.
DR   PANTHER; PTHR47966; BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED; 1.
DR   Pfam; PF00026; Asp; 1.
DR   PRINTS; PR00792; PEPSIN.
DR   SUPFAM; SSF50630; Acid proteases; 2.
DR   PROSITE; PS51767; PEPTIDASE_A1; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|PIRSR:PIRSR601461-2}.
FT   DOMAIN          61..410
FT                   /note="Peptidase A1"
FT                   /evidence="ECO:0000259|PROSITE:PS51767"
FT   ACT_SITE        80
FT                   /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
FT   ACT_SITE        303
FT                   /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
FT   DISULFID        93..130
FT                   /evidence="ECO:0000256|PIRSR:PIRSR601461-2"
SQ   SEQUENCE   415 AA;  45804 MW;  E398EDE75D46CFEE CRC64;
     MQTLASTKQH IKDYDDMKYV TNITFMQTLS STQQHIKDYD DMKYVSNIIV VIPDTGSANL
     WVPDITCSDQ TSSCLVVIPD TGSANLWVPD ISCSDQTSSC PSYCKDSRLC DFLCDESCCT
     HTKHTTDSNC KGKNTFNSKN SYTYQADGRS FTFQYGTGKV SGIFGTDTVG LVGDLNTIQI
     PKTTFGQANT ISNNLGSNAF DGIMGLGFKS LAVDGITPPI INAINQGLFD KPIFTIFLQH
     KDTHNIYGET AGVITYGGFD NDNCNNIINY NDLSSATYWQ FHMSVLNFGY DSYNKYYFEA
     IADTGTSYIG APSWVVDDVT MKAGATYSDK YGLYLIDCNA KLPFTSVEIG GIEYQIPSNY
     LIDQLGNNLC AFTFFSIDGL GYSPQFILGD PFLMSICQVY DVENKRIGFA LPKVN
//