ID   A0A0N4ZCL6_PARTI        Unreviewed;       894 AA.
AC   A0A0N4ZCL6;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=PBPe domain-containing protein {ECO:0000313|WBParaSite:PTRK_0000526900.1};
OS   Parastrongyloides trichosuri (Possum-specific nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Parastrongyloides.
OX   NCBI_TaxID=131310 {ECO:0000313|Proteomes:UP000038045, ECO:0000313|WBParaSite:PTRK_0000526900.1};
RN   [1] {ECO:0000313|WBParaSite:PTRK_0000526900.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC       family. {ECO:0000256|ARBA:ARBA00008685}.
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DR   AlphaFoldDB; A0A0N4ZCL6; -.
DR   STRING; 131310.A0A0N4ZCL6; -.
DR   WBParaSite; PTRK_0000526900.1; PTRK_0000526900.1; PTRK_0000526900.
DR   Proteomes; UP000038045; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR   GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR   CDD; cd13717; PBP2_iGluR_putative; 1.
DR   Gene3D; 1.10.287.70; -; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   InterPro; IPR019594; Glu/Gly-bd.
DR   InterPro; IPR001508; Iono_Glu_rcpt_met.
DR   InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR   InterPro; IPR001320; Iontro_rcpt_C.
DR   PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR   PANTHER; PTHR18966:SF411; IONOTROPIC RECEPTOR 25A; 1.
DR   Pfam; PF00060; Lig_chan; 1.
DR   Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR   PRINTS; PR00177; NMDARECEPTOR.
DR   SMART; SM00918; Lig_chan-Glu_bd; 1.
DR   SMART; SM00079; PBPe; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        515..538
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        595..616
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        811..835
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          389..789
FT                   /note="Ionotropic glutamate receptor C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00079"
FT   DOMAIN          399..461
FT                   /note="Ionotropic glutamate receptor L-glutamate and
FT                   glycine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00918"
SQ   SEQUENCE   894 AA;  103437 MW;  25F2B60BAC38908F CRC64;
     MNVSFLYMKK TVPNDNILYE VIRIKNGSTY EDLCRSISVN TSFIISGVLT KNARKLVGLM
     INITQLPMIQ LKYDINSFII NNTCINEDNS YCASNVSQNY AIELIPAINI FYYSFQQLLP
     HLPFQNDVAI IYDFTVNEMR TNLTFFIKNI KMINASLIEA SNDRKSIIEQ LSILSQMYKT
     LIFMCQTSTV ESYIIEAEQY FTENIFTWII FTTDVMPFKC LDCITVDMFW IRIHHKKRLN
     TIYYIKDFIN NEGLTNQFNE TLKTFNYVQV STYFEIFLAA YNFINVTYFE KVISNNTSCY
     LKRYWEKHPM KSAVFDLENY KSPDYGEYLS LPYNSFILYQ DVGVRIYKIN RRRDLQEGNI
     NKYLGNWTFS SGIVMFYQNF TVDIYLLKHY RIGAIIQPPF TEWGNENENN IKLLEGYCID
     LLNLIQNDLQ FNYTLYLVED GLFGSMDDNG VWNGVVGDIV SGNADFSISA LSVMAEREID
     IDYTVPYYDL VGTTILMKKT VVDNSLFKFL QVFELPVWLA VLGAYCLTSL LIWIFDIISP
     YSFTNLTKNN ENLELENRRK FTPKECLWFC MTSLTPQGGG ETPLNISGRF LSATWWVFGF
     IIIATYTANL AAFLTVSRLE QPISSLDDLA NQYKIEYAPL KGSASEAYFK RMALIEEKFY
     NIWKEISLNE SMNSMDKAKL AVWDYPVSEK FSNLWRIMQQ SKLPDSTKEA INRVLTSENG
     FAFIGDALDI QYAVLTNCDL QTIGNEFSRK PFALGVQTGH PIKDKLSTSI LRLLHQRKLE
     TLKQKWWDNN PNKAKCPTTS DSNYGIKIEN IGGVFIVILA GIIMAIVTLI IEYIYHHRMM
     QKSINIRESN TSTTIQMSNI STSNENDAFE DVEISEHPSN TILRHRTVLQ HDNT
//