ID   A0A0N4ZZ53_PARTI        Unreviewed;      1109 AA.
AC   A0A0N4ZZ53;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   08-NOV-2023, entry version 29.
DE   SubName: Full=Ras-GAP domain-containing protein {ECO:0000313|WBParaSite:PTRK_0001406700.1};
OS   Parastrongyloides trichosuri (Possum-specific nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Parastrongyloides.
OX   NCBI_TaxID=131310 {ECO:0000313|Proteomes:UP000038045, ECO:0000313|WBParaSite:PTRK_0001406700.1};
RN   [1] {ECO:0000313|WBParaSite:PTRK_0001406700.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   AlphaFoldDB; A0A0N4ZZ53; -.
DR   STRING; 131310.A0A0N4ZZ53; -.
DR   WBParaSite; PTRK_0001406700.1; PTRK_0001406700.1; PTRK_0001406700.
DR   Proteomes; UP000038045; Unplaced.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   CDD; cd04013; C2_SynGAP_like; 1.
DR   CDD; cd05136; RasGAP_DAB2IP; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR039360; Ras_GTPase.
DR   InterPro; IPR023152; RasGAP_CS.
DR   InterPro; IPR001936; RasGAP_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   PANTHER; PTHR10194:SF125; RAS GTPASE-ACTIVATING PROTEIN RASKOL; 1.
DR   PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR   Pfam; PF00168; C2; 1.
DR   Pfam; PF00616; RasGAP; 1.
DR   SMART; SM00239; C2; 1.
DR   SMART; SM00323; RasGAP; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50004; C2; 1.
DR   PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR   PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468}.
FT   DOMAIN          187..305
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   DOMAIN          376..570
FT                   /note="Ras-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50018"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          84..113
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          905..989
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1087..1109
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1030..1057
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        10..32
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        90..113
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1109 AA;  126313 MW;  48331F65DD1BE66A CRC64;
     MKIFENFTIK ENPPKTSLSP MNSSSGYSTL TSRESEDIKD DIISIDEKIF NNFEDPNLNN
     DNKNNNNKRS AHKLIRGRTV YKIRRGPDSR QSSENLTGSG MYNKQSQKSS YYGSSVNTLD
     VNQKQKLRNC KSHESLATFS NASHMIDLNS IDTQLHPVHP SVLGVANCFK VANTYYACRT
     QSERAKWIEN LRRTMNPRRD QSRRTENALQ IWVLEAKGIQ SKRNYFCEIC LDKTLYARTS
     SKPKSDICFW GEYFDFSMLP NVEDVCINLY KEADSKKRKD RTTLVGYVQI KMDQLLSRYP
     VERWYTVKVG SEGFSNKLTS NWVSKTSSEQ ASIRVKARFQ TVDVLPMHVY DHLLYFIKEN
     YLPLCLALEP MLSVKAKEDF ANSLVKVLHK QRCVKEFLCD LIMSEVDVLD NEHLMFRGNS
     LATKAMEGYM KLVADDYLQE TLGDFIKMVL EGNDNCEVDP MKLPNSSSNL LDRNRQQLIF
     LCEAAWSKII VSLKFFPTEL KQVFDLLRRR LIASNRGELA DNLISSSIFL RYLCPAILSP
     SLFSLVSEFP NPQVSRNLTL IAKTIQTLAN FNKFGGKEHY MEFMNDFVTR EWDNMHSFLL
     KISSNNSMTF DMSLQSTAAI TNLDVLIDSG KELSLLYHYL EEVWSHEFHE KTCLEEPNLS
     PLKDILMDIS LSKNRNYDIS PVHESRISGN YSPPSDYENG TPLSYNQRLE ASRNQNIFKS
     RENALNHDGV ANRNSFINNE CDGVPLVLSS KSQQVDLNNL KYSRNSLYNS KEHIDNNQGY
     FEPKQYSIYD DTAISKNSNN LLHNIYEQYH IYDEVAHPNN KIMESSIGHK DLLLTTRSKP
     SCSYSSSSQG TSDLVDSELS DMEVTFKGVN KPIRRQKRKS VADAQVILDG RNHIHNALSI
     PFSSGYQSNS QNSPISSNST SPVELSLPSK NVVVRKQINT SKNGSRQRRP SSPLFVHSYS
     NSTGTTSSTT SSAAADSGIG TSNNSSKILP SRHINGIWHS TQSESSDVLD AEKSLESLSI
     HNNKYISVEK TNQQMIIENQ KKEIERLIRE NEILRRQMTT NVSSSNSIDS EKFNLDNKTD
     KIELNENNGL KQFSSNDTSK TTNKKLSPC
//