ID A0A0N4ZZA6_PARTI Unreviewed; 776 AA.
AC A0A0N4ZZA6;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=DNA_MISMATCH_REPAIR_2 domain-containing protein {ECO:0000313|WBParaSite:PTRK_0001411900.1};
OS Parastrongyloides trichosuri (Possum-specific nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Parastrongyloides.
OX NCBI_TaxID=131310 {ECO:0000313|Proteomes:UP000038045, ECO:0000313|WBParaSite:PTRK_0001411900.1};
RN [1] {ECO:0000313|WBParaSite:PTRK_0001411900.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
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DR AlphaFoldDB; A0A0N4ZZA6; -.
DR STRING; 131310.A0A0N4ZZA6; -.
DR WBParaSite; PTRK_0001411900.1; PTRK_0001411900.1; PTRK_0001411900.
DR Proteomes; UP000038045; Unplaced.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0007127; P:meiosis I; IEA:UniProt.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR PANTHER; PTHR11361:SF20; MUTS PROTEIN HOMOLOG 5; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 177..489
FT /note="DNA mismatch repair protein MutS core"
FT /evidence="ECO:0000259|SMART:SM00533"
FT DOMAIN 507..698
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|SMART:SM00534"
FT REGION 11..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..31
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 776 AA; 89251 MW; 70845A49B4DF9288 CRC64;
MDFINYVKGK GDEPRRDIFD FEEKESNEDV VQETQYNEDE EGDDTPRGPI KQFQVTEFPS
HTYSLTNALR LIDEMHKSGQ YKESDVELHN RAFKINLIYV NMVQSIGALL RLLDQHRVGV
EFEDYSVKTP IKQIRKLTIN KLMEIDHYSI MALDIFDNEY HPSATKVFGR RWGNKPQKGM
SVFKICNHCS SVVGKLLLKQ WFEKPLTDFK AITERHDAVQ FFMDESKLEM VKQFRNHLGY
IKRMEPILKR FREGTVQSGD WRIFYNTVAC SYNIGSTLKE SGTNLKILDQ YMNAFCPEMM
DLLTLFTEVI DFNETAAQDK FSVKRGIDSE LDRLKNFFND MEGFLTEAAK REFEEYHLQG
CSVVYVPVLG YLLVLSDDHK PLEGVNITLA LNSRGKNYYK TPLMMELDAN VGDVKLKIRD
METNTLLKLQ KLVVENAGKI RIMIKAVAIV DCVMSFAAVS KELNWCRPTM VKESIIEMTE
ARHPIAECLA PDLYVPNPVM SGGESYTKVK LLTAPNTSGK SVYLKMIAVC CYLAQIGCYV
PATTATIGII DAIVIRMYTL DSVMDGLSTF AQDMRQMGIA LNRGTGNSLV IIDEFGIGTM
KEAGLALYAS TLNYWLAKGR NDCPHIFASS HFHSLPLYVN STSKLLSYHT MEVEKKESTL
NFFYRLIDGT VTKSYANYIA LKKGVPDKII ERSEQVYEEL KNGKDVYEIE KLHFDDDERD
GQIFKIMDDH MVEFERCETN EDYLKFLETL KTEIIQLFED DESTEFNFNE TTKFFF
//
