ID   A0A0N5BD67_STREA        Unreviewed;       804 AA.
AC   A0A0N5BD67;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=CULLIN_2 domain-containing protein {ECO:0000313|WBParaSite:SPAL_0000395700.1};
OS   Strongyloides papillosus (Intestinal threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0000395700.1};
RN   [1] {ECO:0000313|WBParaSite:SPAL_0000395700.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
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DR   AlphaFoldDB; A0A0N5BD67; -.
DR   STRING; 174720.A0A0N5BD67; -.
DR   WBParaSite; SPAL_0000395700.1; SPAL_0000395700.1; SPAL_0000395700.
DR   Proteomes; UP000046392; Unplaced.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF76; CULLIN-5; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
FT   DOMAIN          420..663
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
SQ   SEQUENCE   804 AA;  94115 MW;  5D41888484AA7821 CRC64;
     MTCTEAANDG SVSNGDTTKV IRQTYTRKPI DFDTYWDSAL LIVRDLMDRK NVSRQRWHEL
     FSLVFNICTW DDEGKEKINK RLHNEFSIYI SLAEKRIHSS GDNLETLKLY IAEWDRFYVL
     SQHLPLPFRV KTYKKGDSRY RIHDAFIRGF EDSENDIRNL MYTIWSDIIF SHLKLTLWAS
     VEKLITDERN GVQIDENLIV GVRQSFVLLC PDQSCKMGIY NSIFLENYLK FTDEFYKIKT
     SEVKAVTGIR EYLNYMNSKL DEEEQRARKY LNNDPESLKK LEEVIVNVLV TQFADEILSE
     VRSLIKDNDV PRLSIIYKAL NKTSDKMESV LEVLKEYITE EGLSTMRENA LTVASDPEKF
     VEQLLTMYSK FSKLIDEAFN GDIRFKTIRD VAFNIVANST DVFKMEIPTR VKGRCNIESR
     CPELLANYCD LLLRKSGLSK RLSSSEIDKK LNDLLLVLKY VNSKDIFIKY HKNHLSRRLI
     MEAYTDIERE EYIVNQFKEC GMPTETIGKM YRMLQDLDLN KDFNTFIKTS KNIKNNNRDG
     TQNDKDISDL LNVKILNEGA WGRGKDFVNV TLNDNLEEAM HSIENLYKFK HKGRKLNWIH
     QWSHGTMTFT SNNGKYDLDM SAFQMAVINC FFHCSRGKLS FEALKLATKL PINELTRTLV
     SLTAFPKIKS QVLLTDCESV TSRNFKDETL FWINHDFFIV KNNTMQSRGK LNLIGRLQLA
     AEVSSQLEQD EIVTLRELRT QEAITKIMKM RKECSCSHLE NEVVEMLKNI FYPNKKLIKE
     QIEYLINEKV IERHKKKQNV FVYL
//