ID A0A0N7I377_9MICO Unreviewed; 472 AA.
AC A0A0N7I377;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=GntR family transcriptional regulator {ECO:0000313|EMBL:ALJ18551.1};
GN ORFNames=AOA12_00920 {ECO:0000313|EMBL:ALJ18551.1};
OS Microbacterium sp. No. 7.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=1714373 {ECO:0000313|EMBL:ALJ18551.1, ECO:0000313|Proteomes:UP000059097};
RN [1] {ECO:0000313|EMBL:ALJ18551.1, ECO:0000313|Proteomes:UP000059097}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=No. 7 {ECO:0000313|EMBL:ALJ18551.1,
RC ECO:0000313|Proteomes:UP000059097};
RA Ohtsubo Y., Nagata Y., Numata M., Tsuchikane K., Hosoyama A., Yamazoe A.,
RA Tsuda M., Fujita N., Kawai F.;
RT "Complete genome sequence of a polypropylene glycol-degrading strain
RT Microbacterium sp. No. 7.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP012697; ALJ18551.1; -; Genomic_DNA.
DR RefSeq; WP_054678883.1; NZ_CP012697.1.
DR AlphaFoldDB; A0A0N7I377; -.
DR STRING; 1714373.AOA12_00920; -.
DR KEGG; mio:AOA12_00920; -.
DR PATRIC; fig|1714373.3.peg.197; -.
DR OrthoDB; 4307011at2; -.
DR Proteomes; UP000059097; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000059097};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 22..90
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
FT REGION 88..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..113
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 472 AA; 48910 MW; 7517576F5331EF48 CRC64;
MTVADTTART TTAGWLLERL PGRGARDIAD GIAGLIASGD LAIGAQLPTI RDLARAADVS
AGTVLAAWNQ LRAAGLIETH RRGGTIVVDD GGTAASADAS RQRARTNGPR TGGPRTWATI
DLLQCAPDIS LQPGLRDALM ESLSDESLNV FGREHMTERL HDAVAPTWPF AAEAWATAGG
GTEALLLAVA AAAEPGSLVA VHEPASPGLL DTLRVLSLTP VGVACDDDGP LVGSLRAAID
AGAVAFVVQP GGEFALSGRV TAQRMDDLAA AIAAAPQHVW VVEDDAVGPL AATESPSMGT
ALPGRTIRVR SYCKAYGIDV RTSVLGGSRE LVERSIALRS HGVGSNSRIL QNALAHLIDS
PAAAESVERA RRVYASRREA LRDALERHGL TAAAAPEGLV LWVDVVDETD ALVALATKGV
SVAPASKVFI APPERPMIRI SPLQLPDDPA AIDELATLVS GAARGTTREF FD
//
