ID A0A0P0NPH2_9SPHI Unreviewed; 466 AA.
AC A0A0P0NPH2;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Carboxypeptidase Q {ECO:0000256|ARBA:ARBA00014116};
DE AltName: Full=Plasma glutamate carboxypeptidase {ECO:0000256|ARBA:ARBA00033328};
GN ORFNames=AQ505_23835 {ECO:0000313|EMBL:ALL08960.1};
OS Pedobacter sp. PACM 27299.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=1727164 {ECO:0000313|EMBL:ALL08960.1, ECO:0000313|Proteomes:UP000062859};
RN [1] {ECO:0000313|EMBL:ALL08960.1, ECO:0000313|Proteomes:UP000062859}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAMC 27299 {ECO:0000313|EMBL:ALL08960.1,
RC ECO:0000313|Proteomes:UP000062859};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer. The monomeric form is inactive while the homodimer
CC is active. {ECO:0000256|ARBA:ARBA00025833}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum
CC {ECO:0000256|ARBA:ARBA00004240}. Golgi apparatus
CC {ECO:0000256|ARBA:ARBA00004555}. Lysosome
CC {ECO:0000256|ARBA:ARBA00004371}.
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DR EMBL; CP012996; ALL08960.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P0NPH2; -.
DR STRING; 1727164.AQ505_23835; -.
DR KEGG; pep:AQ505_23835; -.
DR OrthoDB; 9769665at2; -.
DR Proteomes; UP000062859; Chromosome.
DR GO; GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0070573; F:metallodipeptidase activity; IEA:InterPro.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR039866; CPQ.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR007484; Peptidase_M28.
DR PANTHER; PTHR12053:SF3; CARBOXYPEPTIDASE Q; 1.
DR PANTHER; PTHR12053; PROTEASE FAMILY M28 PLASMA GLUTAMATE CARBOXYPEPTIDASE-RELATED; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 4: Predicted;
KW Aminopeptidase {ECO:0000313|EMBL:ALL08960.1};
KW Carboxypeptidase {ECO:0000256|ARBA:ARBA00022645};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Hydrolase {ECO:0000313|EMBL:ALL08960.1};
KW Lysosome {ECO:0000256|ARBA:ARBA00023228};
KW Protease {ECO:0000313|EMBL:ALL08960.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000062859}.
FT DOMAIN 116..205
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 231..422
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
SQ SEQUENCE 466 AA; 50609 MW; 30C101E7A81DBAE2 CRC64;
MKVQGNFGPV FQQINAEVQA NSKAYDNLKF ATENIGHRLT GSANGAKAEA YAYQLLKSYG
YEVKFQPFEV ESWSRISNET KIGDSEKELK KVNSVTLAHS PVKTSVFGEL IDLGNGLEAD
YIKDGGKVKG KIALVYLGVL PGSAEKTPYL HRSEKAAIAI QHGARGIILI NGVKGGVLLT
GTASVTGKLI PIPALCIGLE DGMALKETLK SKPQYASLNM SNFSGLIKAR NVIATLKGTT
LPAEKIVVGG HLDSWDLATG AIDNGIGSFA IIDMARTFKK LNLKTARTLE FVLFMGEEQG
LLGSKAYVAA EHKQNTLDKV RFMLNYDMAN NPKGFSTSRK EMKDLFNAWG SQINQLDSGF
KNIFYAGAGL HSDHQPFLLE GIPTGGGAGE VLPNNSGPFY HSDGDVFSLV DDQELRNTVR
FSAMLAYALA NTPNIPVSRQ SNEVLKKFLQ ENDLEVPLKI AGEWKW
//
