ID A0A0P0SHK6_9PSEU Unreviewed; 918 AA.
AC A0A0P0SHK6;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=HTH luxR-type domain-containing protein {ECO:0000259|PROSITE:PS50043};
GN ORFNames=AD017_25940 {ECO:0000313|EMBL:ALL83776.1};
OS Pseudonocardia sp. EC080619-01.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Pseudonocardia.
OX NCBI_TaxID=1096856 {ECO:0000313|EMBL:ALL83776.1, ECO:0000313|Proteomes:UP000066228};
RN [1] {ECO:0000313|EMBL:ALL83776.1, ECO:0000313|Proteomes:UP000066228}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC080619-01 {ECO:0000313|EMBL:ALL83776.1,
RC ECO:0000313|Proteomes:UP000066228};
RX PubMed=26535611; DOI=10.1021/jacs.5b09794;
RA Van Arnam E.B., Sit C.S.;
RT "A Rebeccamycin Analog Provides Plasmid-Encoded Niche Defense.";
RL J. Am. Chem. Soc. 137:14272-14274(2015).
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DR EMBL; CP012184; ALL83776.1; -; Genomic_DNA.
DR RefSeq; WP_060575850.1; NZ_CP012184.1.
DR AlphaFoldDB; A0A0P0SHK6; -.
DR STRING; 1096856.AD017_25940; -.
DR KEGG; pecq:AD017_25940; -.
DR PATRIC; fig|1096856.3.peg.5475; -.
DR OrthoDB; 3178131at2; -.
DR Proteomes; UP000066228; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd06170; LuxR_C_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF00196; GerE; 1.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00421; HTH_LUXR; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000066228}.
FT DOMAIN 849..913
FT /note="HTH luxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50043"
FT REGION 793..871
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 793..810
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 820..837
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 918 AA; 95550 MW; 3FC0E687F848E879 CRC64;
MPRPVLVDRD DDLGAVDAAV DRAVGGSGSL LVFTGPLGIG RTALLDECAR RGTARGVRVL
RARGTDDERG VPLSTARRLL AVAPTDLPGR AAHGDFEALH AELAAHAADG PVLLLVDDAS
RCDADSLRWF AFLGHRLAGL RVTIVLTALD GDGGHDGGAG PVPADLVGQA GAVRPLRPLS
DGAVAVAARA GLGRDATPVV VAALAEATGG NPLFLAAVVE EVAAGPHGCQ ETLAHRVREC
APARLRDRLA RAVRRMPEPE RRYLTAVAAA GDVTDDTMLG RLAGLDATDT AAAGSVARRM
GLTGPAEHRL RHRVVGHALD VVQSSGQRRD THLRAAELLR DFGGSSDRVA LHLLAVGGPA
PGWAIDALRE AAGPAAGRGE PWTAIRYLRH ALLAEPGEAE RARVLVDLAG LERCLDAGLA
LRRVVQAVPL LGPVRDRAEA LCRVTPLALE GAAPPVIAML RGVAGELGRA VAGDTGDAAG
RELALRLEAR LHYVDKHTRA GLSAAAARLD ELERRPGGLP LDTPGERELA CVLVHSAAVG
GHRPAARVAA VCRAVLAREP ASSEHVHSTV GMLVTCLCMA DAVEDLPAWL SVAAGHARTE
RAGVAEAVIR AELAAVLLCS GRPAEAEEEV RRSVDLVDDL ADDSLLPGMV LAPVLTAVHH
PSGAERVLAR YGAAPSVPPG FGACLQMLRA RAAVEAGDAD TALEYCLDAG RRFERAGWTA
TPVPWRPWAV EILGGRGRWP EARALAEQEV ARARRWGAPT QLGRALRMLG ELSAPARAGE
LLTEAVTVLD TAGDRTESDR AVRAVAAHRD RAADPGTGPL PRTPRAPAEP PRGDAPAGAP
APAGRPGGDA PPAPALTRSE RRVATRAAQG RTNQEIAGDL AVSVRAVEKH LTGVYRKLGV
SGRAALRRVW EGGSDRIA
//
