ID A0A0P7AR15_9HYPO Unreviewed; 875 AA.
AC A0A0P7AR15;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=MutS 4 {ECO:0000313|EMBL:KPM34986.1};
GN ORFNames=AK830_g11584 {ECO:0000313|EMBL:KPM34986.1};
OS Neonectria ditissima.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Neonectria.
OX NCBI_TaxID=78410 {ECO:0000313|EMBL:KPM34986.1, ECO:0000313|Proteomes:UP000050424};
RN [1] {ECO:0000313|EMBL:KPM34986.1, ECO:0000313|Proteomes:UP000050424}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R09/05 {ECO:0000313|EMBL:KPM34986.1,
RC ECO:0000313|Proteomes:UP000050424};
RA Gomez-Cortecero A., Harrison R.J., Armitage A.D.;
RT "Draft genome of a European isolate of the apple canker pathogen Neonectria
RT ditissima.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPM34986.1}.
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DR EMBL; LKCW01000283; KPM34986.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P7AR15; -.
DR STRING; 78410.A0A0P7AR15; -.
DR OrthoDB; 168255at2759; -.
DR Proteomes; UP000050424; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR011184; DNA_mismatch_repair_Msh2.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR PANTHER; PTHR11361:SF21; MUTS PROTEIN HOMOLOG 4; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF005813; MSH2; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000050424}.
FT DOMAIN 275..601
FT /note="DNA mismatch repair protein MutS core"
FT /evidence="ECO:0000259|SMART:SM00533"
FT DOMAIN 619..810
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|SMART:SM00534"
FT REGION 1..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 444..471
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..27
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..91
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 875 AA; 97302 MW; 6D943647163C1C71 CRC64;
MPGAPSSSSA ASRTASRSSS VYFQNNDRRL RPDNRSMPSG INRPPTSLSL GSAYPSGPST
RPSTSRPSTA RPRTRQSTPS GRKSRTATAS SILGLTESHS IVCAVSEARG VSPAVGVAFV
NVSIGEVVLS QICDNQSYVK TIHKIQMSAP SHILFMSTAC APSAPSTLCS LVQELVPEAQ
VDGLDRSAWS ETEGLEYIQS LAFKDDIEPL KVATHGKFYA ISSFAAAMKF IHHKFSINFV
PHSLRIQYRP SEDTMMIDIS AIQSLEIMQN LRNPKSKECL FGLLNHTSTP MGSRMLRSNI
LQPPTREEAF INPRYDALEE LTTNEEMFCE IRKALKLFHD VEKLLTKLII VPSSGDIQQV
EEQINQVLMV KSFLEAIPEL YAALEPATSV LLVKIRHLCR PEIRRRTLET IRKTIEADVT
YMKSPLDLRN QRTFAVKAGI SGMLDVARQT YKELTEEIHK HIDELNEAHG LDANLRFDNG
RKYWLRLRAA DFDDRPLPDV FIYAVRKKDK IECQTLDLVK LNLRLSDTSN EVVIRSDSVI
QTLLKEIRHE APHLFRVCES VALVDMISSF GQLATTRDYV RPDISGTLAL KAARHPVLDK
TMAGSFVPND YYATEQYCFH IVTGCNMSGK STYIRAVALL QIMAQVGSFV PAEYAAFPII
HNIFARVSLE DNIESNLSTF SVEMREMAFI LRNIDDKSLA VVDELGRATS TRDGLAIAIA
MSEALIQSKA SVWFATHFTD LTRILADRPG VLNLHLAADS STTVDGLPQI TMLYKATSGA
IGDEERYGIN LARAIGLPQT FINKADEVSK DLRQKTEASK RSSESTKLSA RRKLTLNLHG
ALKQARDSGS EEALPGYLKR LQEEFIVRME EVENL
//
