ID A0A0P7B7N5_9HYPO Unreviewed; 730 AA.
AC A0A0P7B7N5;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Sorting nexin MVP1 {ECO:0000256|ARBA:ARBA00014268};
GN ORFNames=AK830_g10173 {ECO:0000313|EMBL:KPM36405.1};
OS Neonectria ditissima.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Neonectria.
OX NCBI_TaxID=78410 {ECO:0000313|EMBL:KPM36405.1, ECO:0000313|Proteomes:UP000050424};
RN [1] {ECO:0000313|EMBL:KPM36405.1, ECO:0000313|Proteomes:UP000050424}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R09/05 {ECO:0000313|EMBL:KPM36405.1,
RC ECO:0000313|Proteomes:UP000050424};
RA Gomez-Cortecero A., Harrison R.J., Armitage A.D.;
RT "Draft genome of a European isolate of the apple canker pathogen Neonectria
RT ditissima.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for vacuolar protein sorting.
CC {ECO:0000256|ARBA:ARBA00002474}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Membrane {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPM36405.1}.
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DR EMBL; LKCW01000205; KPM36405.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P7B7N5; -.
DR STRING; 78410.A0A0P7B7N5; -.
DR OrthoDB; 45524at2759; -.
DR Proteomes; UP000050424; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR CDD; cd07597; BAR_SNX8; 1.
DR CDD; cd06866; PX_SNX8_Mvp1p_like; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR028662; SNX8/Mvp1.
DR InterPro; IPR035704; SNX8/Mvp1_PX.
DR InterPro; IPR045734; Snx8_BAR_dom.
DR PANTHER; PTHR47554; SORTING NEXIN MVP1; 1.
DR PANTHER; PTHR47554:SF1; SORTING NEXIN MVP1; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF19566; Snx8_BAR_dom; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000050424};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 351..465
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 165..253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 269..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 186..211
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..238
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..253
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 275..291
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..323
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 79846 MW; 540DCD9D98443051 CRC64;
MSLFGSSPPD DESPMVTSPP ARAGGGLFDA EAESKASSSS LFADDGGHGD GGSPWDMPTP
RKQQSRADLI RNLLPASDVP DSYIETFDVA LREDGAGGRV AAGGIAKLFA AARLGADAQA
RIMALVAPAG GDVALGRNEF NVVLALVGLA QEGEVISLDG VDERRRNLPQ PKLPGITAEP
ILPPVGELSA KPPQTPPKDT PPTPRQPKLP RPAMADPDDD PWNTPDLHKT HDHSNVKPNG
ARNHGTNGHT GFVEPTVTAS IAPTAIAQYV PPTSPPAANG GQQTASTTPS APGPGGWGYF
DGNNAAVGGF GETPQSSDPN PFGGPDRTPS GNPPPGLPQH QSSSRIGHSP EENVVVTLMP
EKEGIFMFQH HNYEVSSLRR GSKVIRRYSD FVWLLDCLHK RYPFRILPLL PPKRMGVNGS
HLSNDGAFIE KRRRGLARFL NAVVRHPVLS QEQLVIMFLT VPTELAVWRK QATISVQDEF
AERALLPGLE DSLPPTLEEL FTRTQAGIKR SAELYITVCN IMDRLVKRTE GVAADHARIA
LSLASLTEAS ADTYATDTNE VPLLNDGLVA MSKHLRTCQA LMEDESRGWD EGVLEDLKRQ
RDALVSMREM FERRERLDKD NIPYLERRIQ TNETKLANLR SKPEGLVKPG EIERVAENII
KDKESIVQQH NRSIFVKECI RDELVTFQTT QYHVSRWNQD WAGERVKYAE MLADNWRRLL
DELEGMPLGD
//
