ID A0A0P7BB90_9HYPO Unreviewed; 716 AA.
AC A0A0P7BB90;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Peptidase S8/S53 domain-containing protein {ECO:0000259|Pfam:PF00082};
GN ORFNames=AK830_g8908 {ECO:0000313|EMBL:KPM37675.1};
OS Neonectria ditissima.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Neonectria.
OX NCBI_TaxID=78410 {ECO:0000313|EMBL:KPM37675.1, ECO:0000313|Proteomes:UP000050424};
RN [1] {ECO:0000313|EMBL:KPM37675.1, ECO:0000313|Proteomes:UP000050424}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R09/05 {ECO:0000313|EMBL:KPM37675.1,
RC ECO:0000313|Proteomes:UP000050424};
RA Gomez-Cortecero A., Harrison R.J., Armitage A.D.;
RT "Draft genome of a European isolate of the apple canker pathogen Neonectria
RT ditissima.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPM37675.1}.
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DR EMBL; LKCW01000158; KPM37675.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P7BB90; -.
DR STRING; 78410.A0A0P7BB90; -.
DR OrthoDB; 2591581at2759; -.
DR Proteomes; UP000050424; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF54897; Protease propeptides/inhibitors; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000050424};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..716
FT /note="Peptidase S8/S53 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013380108"
FT DOMAIN 186..429
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT REGION 480..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 569..591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 570..588
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 195
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 232
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 411
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 716 AA; 78371 MW; 7AF0F965F22B65E5 CRC64;
MRLLIPFLFS PYVLGALLPR AEAPCPYHRP NAKLIEDEYI VVLHRGHTLQ KHFDQIGSDL
TVNASMFYSI DTINGYRAKL PQDFVHDHIR FDPGVEFVEH DHSISLIEPI FEGEDDSAYE
DSTEAQPGFF RGLLNRLHNF RRDNWWHWQI SHRDGAWYDA MKSFGKKHNP MWWWTKQSWQ
VLDGAGKGVN LYVIDTGVRL SHSNFQGRAI NFHLENTSPY VGGATADDKH GHGTHVAGTA
AGARGGMAPW ATIVNVKVMC QHDEPNCRGD SGGGLTQAIS DITSEHNNFK NGNDKTMPGW
KGSVINMSLT TGDSEALRRA MKEAFDAGIP IAVAAGNNRQ NTADVVPCKY TESSVCVASS
DIDYKFSTIF NNNPKFGSNY GREVKMIAPG SEISSSYNTD DRKYAWLSGT SMASPVVAGA
MAIFVSFENL DNDVNKVWDR LVKNQLVGII SDVPSDPPTA NNFVNSGINS VLKNEHEPYY
GALSIDHPPG DDSGSEVKAA EDEPQQGPTN WEENPDSGPG FETLGVSNSD PDAVVVVTEE
YIGPVETEGP NPDADADVGF EGDISMDNSS PPADKLQCAP TDSNGPKLSR GNIEGKINTW
CDSLNLGTIS QDDTRKEEVS SFGSSTPGTK LTDLIFSANW VKDVVGEGCP ERTRGTEPKH
CKKAMYEVLD SCGGKDGMDS GSPRYGGSQQ GDEQCVIWKI EIEDVGTQTK RGQIMD
//
