ID A0A0P7EA76_9GAMM Unreviewed; 542 AA.
AC A0A0P7EA76;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Choline dehydrogenase {ECO:0000313|EMBL:KPM80681.1};
GN ORFNames=AOG28_07195 {ECO:0000313|EMBL:KPM80681.1};
OS Cobetia sp. UCD-24C.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Cobetia.
OX NCBI_TaxID=1716176 {ECO:0000313|EMBL:KPM80681.1, ECO:0000313|Proteomes:UP000050261};
RN [1] {ECO:0000313|EMBL:KPM80681.1, ECO:0000313|Proteomes:UP000050261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCD-24C {ECO:0000313|EMBL:KPM80681.1,
RC ECO:0000313|Proteomes:UP000050261};
RA Krusor M., Coil D.A., Lang J.M., Eisen J.A., Alexiev A.;
RT "Draft Genome of Cobetia sp. UCD-24C.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPM80681.1}.
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DR EMBL; LJTD01000004; KPM80681.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P7EA76; -.
DR STRING; 1716176.AOG28_07195; -.
DR PATRIC; fig|1716176.3.peg.2148; -.
DR Proteomes; UP000050261; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Reference proteome {ECO:0000313|Proteomes:UP000050261}.
FT DOMAIN 258..272
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 82
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 218
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 542 AA; 58975 MW; 27BACDF8DF2DB3FE CRC64;
MQYDFIIVGA GSAGCILANR LSANGRHKVL LLEAGGKDTS PWIKVPVGFA KTYYNPAYNY
MYYSKEEAAM GGRKIYTPRG KVQGGSGSIN AMIYVRGQAS DFDDWARAGN DGWSYREVLP
YFKRLECHPG GDTEYRSGQG PIGITPLKHG AHPICQSWLE GARELGYTLN DDFNGKHFEG
AGIYEANIRK GQRDSSNTAY LKPALSRDNL TLKHICRVER VTLEETPDGG KRATGVAYRL
DDEVIEVTAR REVILCAGAV DSPKLLQLSG IGEREALATH GIETQVDLPA VGQNLQDHLC
ASYYYRANRT TLNDDFASFW GQAKAGLQYL INRSGPLGMS VNQAGGFFRG SEAESEPNIQ
LYFNPMSYQI PNDPRAKLTP EPYSGFLLAF NSCRPTSRGS ISLSSADPTD PATICPNYLS
TQKDIDEVIQ GSRLVRKLMG APALKAITEY EVAPAETVHD EDSMLAYFRS QGGSIYHLCG
SCAMGPDKAN AVVDSRLKVH GVAGLRVIDA AIFPNITSGN LNAPVMMVAE KGADLVLADH
AD
//
