ID A0A0P7HYK9_9RHOB Unreviewed; 392 AA.
AC A0A0P7HYK9;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:KPN61657.1};
DE EC=2.3.1.9 {ECO:0000313|EMBL:KPN61657.1};
GN ORFNames=AKJ29_03345 {ECO:0000313|EMBL:KPN61657.1};
OS Aliiroseovarius crassostreae.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Aliiroseovarius.
OX NCBI_TaxID=154981 {ECO:0000313|EMBL:KPN61657.1, ECO:0000313|Proteomes:UP000050471};
RN [1] {ECO:0000313|EMBL:KPN61657.1, ECO:0000313|Proteomes:UP000050471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CV919-312 {ECO:0000313|EMBL:KPN61657.1,
RC ECO:0000313|Proteomes:UP000050471};
RA Kessner L., Spinard E., Nelson D.;
RT "Draft genome sequence of Aliiroseovarius crassostreae CV919-312TSm, the
RT causative agent of Roseovarius Oyster Disease (formerly Juvenile Oyster
RT Disease).";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPN61657.1}.
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DR EMBL; LKBA01000025; KPN61657.1; -; Genomic_DNA.
DR RefSeq; WP_055192988.1; NZ_LKBA01000025.1.
DR AlphaFoldDB; A0A0P7HYK9; -.
DR STRING; 154981.AKJ29_03345; -.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000050471; Unassembled WGS sequence.
DR GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919:SF138; ACETYL-COA C-ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:KPN61657.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000050471};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:KPN61657.1}.
FT DOMAIN 4..262
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 270..391
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 88
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 348
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 378
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 392 AA; 40549 MW; 5C865FC508DBE953 CRC64;
MKNVVIAGAS RTPMGGFQGA FTGVTASELG GAAIKAALED AGAKPNQIEE LLMGCVLPAG
QGQAPARQAG FAAGLGQDVP ATTLNKMCGS GMKTTMIAFD QVALGATDIM VAGGMESMTE
APYILPKMRG GARIGHGAVV DHMFLDGLED AYDKGRLMGT FAEDCAEKFQ FTREAQDEYA
LKSLSNALGA QKSGAFEGEI APVSIKTRKG EVVVSEDEQP GNARPEKIPA LKPAFRKDGT
VTAANASSIS DGAAALVVAS EEAAQAAGLK IRARIVGHAS HAQEPGWFTT APVPAAQKLL
DRLGWKAEDV DLWEVNEAFA VVPMAFMHEF GLSRDKVNVN GGACALGHPI GASGTRIIVT
LLNAMEKRGL KRGVAAICIG GGEGTAIAIE RD
//
