ID A0A0P7WCE2_9RHOB Unreviewed; 655 AA.
AC A0A0P7WCE2;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Acetoacetate-CoA ligase {ECO:0000313|EMBL:KPP84664.1};
DE EC=6.2.1.16 {ECO:0000313|EMBL:KPP84664.1};
GN Name=acsA {ECO:0000313|EMBL:KPP84664.1};
GN ORFNames=HLUCCO07_06060 {ECO:0000313|EMBL:KPP84664.1};
OS Rhodobacteraceae bacterium HLUCCO07.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae.
OX NCBI_TaxID=1666914 {ECO:0000313|EMBL:KPP84664.1, ECO:0000313|Proteomes:UP000050369};
RN [1] {ECO:0000313|EMBL:KPP84664.1, ECO:0000313|Proteomes:UP000050369}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HLUCCO07 {ECO:0000313|EMBL:KPP84664.1};
RA Nelson W.C., Romine M.F., Lindemann S.R.;
RT "Identification and resolution of microdiversity through metagenomic
RT sequencing of parallel consortia.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPP84664.1}.
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DR EMBL; LJSU01000024; KPP84664.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P7WCE2; -.
DR STRING; 1666914.HLUCCO07_06060; -.
DR PATRIC; fig|1666914.4.peg.1433; -.
DR Proteomes; UP000050369; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:KPP84664.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 39..92
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 97..467
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
SQ SEQUENCE 655 AA; 72077 MW; BCAC7EE78AAE1B83 CRC64;
MADENPILWT PDADRIENAR IAQYMRWLAA ERGLTFPDYN ALWEWSVREI EAFWTSIIEF
CDLPISGWSE VLPERKMPGA DWFPGATTNF AAQILRPAET RPDDVAIILQ SETFGRQELS
WGELKARVGA AQAGLRAAGV KHGDRVVAVL PNSPEALVSF LAAAGMGAIW SLCAPDMGQV
AILDRFRQID PKLLIAQDGY VNAGKQIDRR ALLDEIAADL PGLVQKVIVP TLGPAPEGWT
PWADFTADKA APQIDMVPFS HPLWIVYSSG TTGNPKPIVH GHGGVLLEGT KQSLHQDLGP
DDRFCWLTSS GWIMWNAQWS ALGQGAAVAL FDGAPNHPDM LEVWRMVARE RLTYFGAGAA
FFDGCRKADV RPGAELDLSA LRSLGSTGSP LSHEGYDWIY AHVKPDVWLA PISGGTDLAG
AFVLGNPMLP VRAGEMQCRA LGNAVRAFDE DGREVIGEVG ELVCTEPLPS MPLMFWGDED
GSRLHESYFD TYPGVWRHGD WIMFTPEGGS IIYGRSDATI NRRGLRLGSS EIYRAVEGLD
EVMDSLVVDL EFLGRESFMP LFVVMKEGHA LDDAMRERIR AAIRRQVSAR FLPDDIVEIA
EVPRTLSGKK LEVPVKKLLL GGDPDKVVNR DSMANPDSFD PFIAYARTRI SADRA
//
