ID   A0A0P7YXD7_9GAMM        Unreviewed;       656 AA.
AC   A0A0P7YXD7;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE            EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN   ORFNames=HLUCCA13_00565 {ECO:0000313|EMBL:KPQ26217.1};
OS   Halomonas sp. HL-48.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Halomonadaceae; Halomonas.
OX   NCBI_TaxID=1479235 {ECO:0000313|EMBL:KPQ26217.1, ECO:0000313|Proteomes:UP000050569};
RN   [1] {ECO:0000313|EMBL:KPQ26217.1, ECO:0000313|Proteomes:UP000050569}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HL-48 {ECO:0000313|EMBL:KPQ26217.1};
RA   Nelson W.C., Romine M.F., Lindemann S.R.;
RT   "Identification and resolution of microdiversity through metagenomic
RT   sequencing of parallel consortia.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPQ26217.1}.
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DR   EMBL; LJZS01000001; KPQ26217.1; -; Genomic_DNA.
DR   RefSeq; WP_027336600.1; NZ_LJZS01000001.1.
DR   AlphaFoldDB; A0A0P7YXD7; -.
DR   STRING; 1479235.GCA_000686925_01669; -.
DR   PATRIC; fig|1479235.4.peg.491; -.
DR   eggNOG; COG3706; Bacteria.
DR   OrthoDB; 9812260at2; -.
DR   Proteomes; UP000050569; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR   PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF00989; PAS; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00091; PAS; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        328..348
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          363..434
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          519..656
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
SQ   SEQUENCE   656 AA;  73567 MW;  B237CC0E238DC842 CRC64;
     MRSTSPRLYL RLLLAVTLPL CLVTSTLLPV LYMDMETRLD GVRAEAKAIL RVGEDTLTRD
     INETLNYALA IAEMPALQQR LEDRSPVDEA GLSSRAPTQL DDFLNTFIHH TPRYSKLVLI
     DNEGNEMLRA PQDTGAEPHQ GRRNHAHTDY FKSASKLFPR DIYLSPPGRN LQYEQLSGDA
     IPVVNIATPF FNSQRERKGV VLLSLNWQYL TQSLYQSMQV NPQAGVLLVD ALGGWLLTQG
     LPQLPYLSFG DNYASAAPTP WSELSGTLEG DINLEGSLLH FQTEDIRTKF YNSLAGRIFS
     TDDTLPWVMG VSLPTPSWQS LLEEETSVLW FLGLIYVIAV AFGVYWAFSS HQQRKLRQHA
     QQQAAEVRGL YENAPCGYHS LNADGIVIKM NQTELHWLGL KADEVIGQLR YRDVISPDTQ
     DAFDAAFAQV IVGQQGEAEC TLLTRHGDQR HVVIQACGYH QRGGFVYSRA TVFDLTERKQ
     LEEKLLAQAM TDPLTGVFNR RYLQSQAAIE ISRGLRHSTP LSLIAIDIDH FKRINDEYGH
     DAGDEVLKRF TSVVSGLLRQ EDLLCRVGGE EFAILLPNTD ISKAEQIAER IRATIDTHEM
     TIELEGIHQT LHITASFGVT HVALNETSLK AALKRADKSL YEAKENGRNR IVVKDS
//