ID A0A0P7ZPH9_9CYAN Unreviewed; 622 AA.
AC A0A0P7ZPH9;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Precorrin-3B C17-methyltransferase CobJ {ECO:0000313|EMBL:KPQ34817.1};
GN Name=cobJ {ECO:0000313|EMBL:KPQ34817.1};
GN ORFNames=HLUCCA11_12820 {ECO:0000313|EMBL:KPQ34817.1};
OS Phormidesmis priestleyi Ana.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Leptolyngbyales; Leptolyngbyaceae;
OC Phormidesmis.
OX NCBI_TaxID=1666911 {ECO:0000313|EMBL:KPQ34817.1, ECO:0000313|Proteomes:UP000050465};
RN [1] {ECO:0000313|EMBL:KPQ34817.1, ECO:0000313|Proteomes:UP000050465}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ana {ECO:0000313|EMBL:KPQ34817.1};
RA Nelson W.C., Romine M.F., Lindemann S.R.;
RT "Identification and resolution of microdiversity through metagenomic
RT sequencing of parallel consortia.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPQ34817.1}.
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DR EMBL; LJZR01000016; KPQ34817.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P7ZPH9; -.
DR STRING; 1666911.HLUCCA11_12820; -.
DR PATRIC; fig|1666911.3.peg.4773; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000050465; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd11646; Precorrin_3B_C17_MT; 1.
DR Gene3D; 3.40.50.11220; -; 1.
DR Gene3D; 3.30.420.180; CobE/GbiG C-terminal domain; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR021745; CbiG_mid.
DR InterPro; IPR021744; CbiG_N.
DR InterPro; IPR006363; Cbl_synth_CobJ/CibH_dom.
DR InterPro; IPR002750; CobE/GbiG_C.
DR InterPro; IPR036518; CobE/GbiG_C_sf.
DR InterPro; IPR038029; GbiG_N_sf.
DR NCBIfam; TIGR01466; cobJ_cbiH; 1.
DR PANTHER; PTHR47036; COBALT-FACTOR III C(17)-METHYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR47036:SF1; COBALT-FACTOR III C(17)-METHYLTRANSFERASE-RELATED; 1.
DR Pfam; PF01890; CbiG_C; 1.
DR Pfam; PF11761; CbiG_mid; 1.
DR Pfam; PF11760; CbiG_N; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR SUPFAM; SSF159672; CbiG N-terminal domain-like; 1.
DR SUPFAM; SSF159664; CobE/GbiG C-terminal domain-like; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 4: Predicted;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:KPQ34817.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KPQ34817.1}.
FT DOMAIN 55..134
FT /note="Cobalamin synthesis G N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11760"
FT DOMAIN 140..234
FT /note="Cobalamin biosynthesis central region"
FT /evidence="ECO:0000259|Pfam:PF11761"
FT DOMAIN 237..362
FT /note="CobE/GbiG C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01890"
FT DOMAIN 374..585
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 622 AA; 67270 MW; CE4C452DDDBD9D96 CRC64;
MFTKLAAITT TPAGLRCLAP LYDAGAQLWI APKMEPTAQA LGLTYQTYDT SLAEYLKDAW
NSYDGFVFCL ASGAVIRLIS PLLTNKTSDP AIIVVDPSSQ FVISLCGGHQ GGGDRLTRRI
SQILGAQPVV TGAANALGLP AIDTLGEPFG WVKGSGDWLG VSSAIAHQQP VQILQEAGSE
LWQKHLPAGH SFQFNFPEFE DRESQPKPQA RVWISPTQRT FAPNSELPRV QWHPRVLWIG
VGCERGTDEA LIAQAIESTC RQHHLAIESV AGIATLDLKA DELGLLKYVE KRNWPLRCFE
AKTLAVIQVP TPSDVVNQEV GTQSVAEAAA IVAAGGEANC LRVKKQVVKQ TGMKGAVTVA
IAQAKHEYTG RIGKLCLVGT GPGSLNQITP AAKAAITDAD VVIGYALYVS LIRPLLRPGQ
IIEGLPITQE RQRAERAIEL AKQGLTVAVI SSGDCGIYGM AGLVLEQLRA DNWDGKTPAV
QVLPGVSALQ SAASRVGAPL MHDFCAISLS NLLTPWEVIQ RRLRSAAEGD FIVALYNPKS
QTRQDQIVFA RDVFLQHRSA ETPVALARSL YRPDEQITLT NLGDMLKHPI DMLTTVIIGN
RSSRNYQGWF ITPRGYLSDL AE
//
