ID A0A0P8XZI0_DROAN Unreviewed; 8926 AA.
AC A0A0P8XZI0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Uncharacterized protein, isoform V {ECO:0000313|EMBL:KPU74944.1};
GN Name=Dana\GF19006 {ECO:0000313|EMBL:KPU74944.1};
GN Synonyms=dana_GLEANR_20542 {ECO:0000313|EMBL:KPU74944.1};
GN ORFNames=GF19006 {ECO:0000313|EMBL:KPU74944.1};
OS Drosophila ananassae (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7217 {ECO:0000313|EMBL:KPU74944.1, ECO:0000313|Proteomes:UP000007801};
RN [1] {ECO:0000313|EMBL:KPU74944.1, ECO:0000313|Proteomes:UP000007801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 14024-0371.13 {ECO:0000313|Proteomes:UP000007801};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. CAMK Ser/Thr
CC protein kinase family. {ECO:0000256|ARBA:ARBA00006692}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CH902646; KPU74944.1; -; Genomic_DNA.
DR RefSeq; XP_014759346.1; XM_014903860.1.
DR EnsemblMetazoa; FBtr0389717; FBpp0349306; FBgn0096018.
DR Proteomes; UP000007801; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR CDD; cd00063; FN3; 39.
DR CDD; cd00096; Ig; 3.
DR CDD; cd05748; Ig_Titin_like; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 78.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR14340:SF24; -; 1.
DR PANTHER; PTHR14340; MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3; 1.
DR Pfam; PF00041; fn3; 39.
DR Pfam; PF07679; I-set; 36.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 39.
DR SMART; SM00409; IG; 37.
DR SMART; SM00408; IGc2; 29.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 21.
DR SUPFAM; SSF48726; Immunoglobulin; 39.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50853; FN3; 39.
DR PROSITE; PS50835; IG_LIKE; 27.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000007801};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 9..102
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 119..209
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 228..321
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 335..426
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 438..533
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 543..635
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 640..728
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1727..1819
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1822..1906
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2100..2197
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2200..2298
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2302..2392
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2400..2495
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2501..2596
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2698..2795
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2801..2896
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2900..2992
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 3000..3095
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3101..3196
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3200..3289
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 3297..3391
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3398..3493
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3497..3587
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 3595..3688
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3694..3789
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3793..3882
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 3886..3983
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3989..4084
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4088..4178
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 4186..4279
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4285..4384
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4485..4578
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4584..4679
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4683..4774
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 4780..4873
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4879..4972
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4976..5066
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 5074..5169
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 5175..5269
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 5371..5464
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 5470..5564
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 5663..5757
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 5763..5858
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 5957..6055
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 6061..6156
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 6160..6251
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 6258..6352
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 6358..6452
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 6458..6553
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 6547..6644
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 6653..6747
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 6753..6849
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 6949..7043
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 7049..7144
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 7150..7245
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 7251..7329
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 7443..7538
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 7544..7639
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 7644..7733
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 7738..7831
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 7836..7929
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 7986..8241
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 8309..8397
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 8434..8509
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 8625..8713
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 8733..8823
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 8832..8906
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 832..999
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1035..1217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1250..1273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1398..1464
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3180..3202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3969..3993
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4957..4976
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6346..6369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6455..6480
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6733..6757
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 8551..8609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 832..914
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 932..948
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 950..982
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1035..1053
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1054..1072
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1073..1100
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1109..1217
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1251..1270
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8556..8592
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 8015
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 8926 AA; 999948 MW; 5E7AB7C1F8DC70CF CRC64;
MGVAEDFAPS FIKKPQLHQE DDGNRLIFEC QILSSPKPDI EWFRSDNKLV EDERTKFKIQ
PDGNNNYTVV LELDDVVEAD AGLYKVKAKN KSGEVSASIN LNFTPADEPK EKQIDGFAPT
FAKKPAIRQE EDGKRLLFEC RVNADPIPII KWVHNGTDVK ESSRHKLTID KDGHSYFATL
EIMNVTVEDA GKYKVNAKNE LGESNATISL NFDSDEAPIP ESADGIKPTF TERPVIRQSE
DGGNVTFECR CVGEPMPTVT WSHGETILSE GNRYKMSLTM DQKLYYMACL EISCVVSTDQ
GEYRALAKNR HGSGVAAINL NFESGSKKIP DGKSPRFPKK PTIRQEEDIL IMECILEAHP
MPEIVWYCSD TEIINNQRTK MTRKVITKDS YSLTLEIKNP TKDDGGSYRC NAINMYGESN
ANIALNFQGA SDVNGFAPSF IEKPRIIPNE SGTLITMKCK CKAKPEPTVT WYRGQEVVEK
NQKIKINIIV VAEDTYELTL EIKDPGASDG GTYRCNVKNE FGESNANLNL NIEAEPELEG
EGPTFIEKPR IVSENNGKLV IMECKVKADP KPDIIWYRNG MAIQEINKIK MSMEQRGDQY
YIKLELLDPQ LDDSGIYKCN IKNSLGELNA NLTLNIEIVP VIKEKPKIIK IIKKRSVVIE
CTVASKFQPK CTWYKEANVV KESTRHVYLV EKIKDGEFAV KLEINDVEES DKGAYKVVAS
NEKGEAVSQV VNLIDIPEED RKPSKPEILK KLVDQKVTES KMFELLIKLT QSDRKCKVEW
YKGNTLLRET KDITTTFDGT IARLTFSTAK SEHTSNYKVI VINEVGKDES SCKVTVEKKD
KKKDEKPKNN DASDANKELK EEENKNKTPE VPEDNLEPAS KAEEIKKMKS QESKEKTKLE
KEEDKTKIFE TQNKADKPVT KLQPKIITKN TEKEVTNVKT DEGKESNEVS SAKIIPQSIS
KKVKSEIPEV NNQQSDLNKN KKTELSSSTD TENEWNEPQA AEEKILKKAE RKASIISVKE
DDSLEVRRQS IINCKEETSI EDSKIEEVRK SSLVVQESKT GSRRSSIIEK NSLEQVDTKK
LDANKNPQEI KEEIPKLKPS ALRRNSKPIE AQKPSEDLPH LRKASIAQPK EESKPEAPKA
KTKPKAKSKP KYEELPEIPD YERPVLEKYE KSEFKPSDFG RDVEIPSKME KPILDGNKKE
PQPESPKNDL LKKTAIIEKT PEEKKELKIG KGKLAYEDDG QDGVSLKPVI IEPQNDSTDG
NSQESKQAER TSLLDTIKQR RRSSIRNLMT KEPIQNESFL GVVLKPVIKD SKEQTLPQQA
KQLTKANILE KLSSTKAIKA HISDLKKPEA VATLIDDYEV PVLEKYDPVK LDNSKSEVPT
PGIITPDTKS SVVKVPVEFP KEEKPKMTKI QQPAAGEPPK IEVIREKRPS LAPEPPSRRG
SLIPPADMGR RPSLIINDER RRPSIDVRRP SVQDLEDLIN KPSTPLRDVG DGGPPSIVDV
QESYSVVEDS TAYLTVGVEG SPAPTFKFYK GVSEILEGGR YKFLTDGQTN TITLCMRKCK
PNDEGKYKIV VSNIHGEDSA EMQLYVSDSS GMDFRAMLKK RRYQKWDKDE QDPNWGDLKE
TEKPLPALKK VERKVESFLS PLIDQFAKEG KDKKVIFEAR FSKPNCKPKW LFRKDEVFTG
SKFKFKQEND TYQLIIMTPK VEDTGKYTIE IGGVSSTAFL NVEEADPTYT FTKTLKKKLE
GFTEHETTLE CAVSSSMANV HWFKDNTKIE SDDPRYLISK DINGNLKLII KESLIEDSGL
YRCQLDKQSD KTECNLRVVE YPYKFVKVLK SQQCVEKDTV TLACEIDDAR GEVQWFRNDE
EIKADKRIQI IKDGRKRKLV IKDCKVTDAG RFKCTTNADK TEAEIIINYQ NRFNKKLKDT
DAVEREKLVL DIELQDQTAP CNWKFNGDPI VPNERIEIKN LGGGKHQIIF NNLEMSDEGE
IECESGQITS KCHLSVRKGE SRPNIDCPDE FTGPISAPVV IEVPFKVSGT KQSPVEAKLF
KDGKPLPVKD VDVCIADDKV IFKIKKPSRD LSGPYQIKLS NGQGEDSKDV HIICQDVPQP
PQDVDITDVY QTSCIVNFKP PTDDGGTPII KYLIERQDIS KKQGWEPVVE VLPSEPLVKK
IDDLVPKKQY RFRLRAVNKI GPSDPATFKS SILAKDPWDE PGKPQSVDLI DWDKDHADLK
WEAPENDGGD LITSYILEYK EKFSNDWVTS KEVDGQTRAA TVDGLKEGQQ YEFRVRAVNR
AGPGEPSDKT KSIIAKCRFV KPFLVGDGLK NITVKKGQTI RYDIKYDGEP EPTATWLKGH
DNIKFDNQRI SLEQLERNSS ITVKKAVRKD TGRYKLVLSN SSGTIESEAQ VVVLDRPLAP
GGPLEPDEIR ANHIKMKWKH PEDDGGCEIT GYTLERMDEE TGRWIPAGEV GPNENSFDFK
GLTPNKKYKF RVKAINKEGE SEPLETSDAI LAKNPYDPPS PPSQPIIDDY DNKSVSLKWN
RPPSDGGRPI THYVVEMKDK FSPTWSEVAQ TEDPTPKCSV EGLKEKMIYQ FRVRAVNKAG
ASEPSQPTDN HLCKHKNLKP QIDRSTFKRV TIKSGRTHKW SVDVIGEPVP TLCWSWRDDI
PLNNGDRIKI ENVDYHTDFA ITNALRKDSG FYTLKAENCN GIDRETVELV VLGKPSSPKG
PLAVGDVSAT GCKLQWKKPD DDGGVPIKEY VVEKMDTATG KWIRVGRSPG EKEPPSFNVT
GLSPGSEYMF RVSAVNEEGE SEPLTSLVGV VAKDPFDEPN KPGAPEVIDH DNESVSLKWM
PPNNDGGAPI QKYIIEKKDK NKPEWEKAIE VSGDKLEAKV GGLQEYGEYQ FRVIAVNKAG
LSPPSDASVP QIVKYKKLKP RIDRTNLKPL LIRAGKPIKY DINVRGEPAP TITWYQNDLE
LKPNELPNNS EIKNIPYNTK ISILDAVRKN TGTYKIKAVN EHGEDEATVE VNILGPPGKP
MGPLAVTDIT KDSCKLKWKK PNDDGGVPIT AYQVEKFDKK QGRWVPVGRS SGNDTEFDVK
GLQEGHEYQF RVRAINEEGE SEPLETDGSI IAKNPYDAAS KPGTPIIDDY DEHMVKLRWE
PPKSDGGVPI VGYIIEKKDK FSPIWDEVLT TNSPAPEAVV KELTEGNVYQ FRVRAVNKAG
ASEPSDATGH HLSKPKNLKP SINREKMNSI KVRAGQAVKF DIDVKGEPAP SLTWIFKEKE
LLHTGKVRLE NEDYNTKLTL LDTSRKDSGQ YRLRAENING VDEADVEVII LDKPSKPEGP
LEVSAVHKEG CKLRWKKPKD DGGVPLTGYV VEKMDTATGK WVPAGSVDSE KTDIEIKGLD
PNHRYQFRVK AINEEGESES LETDSAITAK NPFDVSAPPG LPELEDWDEN HVKLKWEPPI
RDGGSPISCY IVEVMDKDTG EFVKALETDS PICKGIVKKL DEGQQYKFRV RAVNQAGPSD
PSEQTNWHTA KPRYLKPHID RTNLKPVIVK TGLSISLDII IKGEPAPKVQ WLFNGNPLIN
QKDGVQIDNI DYNTKFFVMR AERSQSGKYT IKAINEVGED EAELEISVLG KPAKPEGPLH
VNDVTKHSCK LKWNKPKDDG GAPIDYYEIE KLDPHTSQWL PCGKSTEPEA KVIGLQEGKQ
YKFRVRAVNK EGESEDLETE KPIIAKNPFD EPDKPGRPDP TNWDKDFVDL AWDPPKNDGG
APIQKYIIQM RDKSGRSWVD AATIAGDKTK GTVTGVQEGH EYEFRVVAVN KAGPSDPSDV
SKSVIAKPRH LKPHIDRKNL QKKIMRNGQL LHMDANVKAE PPAKITWVYN GAEIKNSDKI
KIENEDYKTT FVIPKVKRTD CGIYTVTAKN DSGSDTVQVE LEVLCKPSKP KGPIAVSAVL
AESVHLKWDK PEDDGGEPIE HYIVERMDTE TGRWVPVQTT KTPEADVTGL TEGKEYLFRV
KAVNSEGESE PLVSDVPTKA KNPFDPADTP GKPQITDWAA NFCDLKWRAP EDDGGAPITS
YIIEKKDPST GKWQKAFESN TPDCKARVND LIEGKKYQFR VKAVNKAGQS KPSEPSDQLI
AKDRFAPPKI DRTHIKDVTI KAGQPIRYDI KVSGEPPATK AWLHNKARLN SDDTDYNIDI
ESYRTKLAVP FAKRLHSGKY TLKAENESGR DEASFEVIVL DKPGTPEGPL RVSDVHKEGC
MLKWNPPLDD GGLPIEYYIV EKMDTETGRW LSSGRFKEPL AEVCNLEPGH EYKFRVLAVN
TEGESNPLIG EQPIIAKNPF DEPGKPGIPE ASDWDKNHVD LVWRPPINDG GSPISSYIVE
KREKGTDKWI KGAEVTAPEL GEECRASVNN LDENCEYEFR VKAVNAAGPG EPSDSSKFVI
TKPRKLGPKI DRRNIRTYNF RAGEPIFLDI NISGEPAPDV TWQQNNKSVQ STSEYHIENI
PYNTKYINNN PNRKDTGLYK IIALNLYGQD QVELQINIIS KPGKPEGPLE VSEIYKDGCK
LKWKKPKDDG GEPIECYLIE KFDSDTGIWL PVGKTEVPEY NVDGLVSGNE YQFRVKAINK
EGESEPLETF GSIIAKDPFT VPSKPGVPEP TDWTANRVEL SWLEPANDGG SPITGYLIEV
KDKYSPLWEK SLETSSPTPI ATIPGLIEGN EYQFRVVALN KGGQSEPSDP SKTFIAKPRY
LAPKIDRRNL RDVTISSGTA LKLDANITGE PVPKVEWKLS NYPLQSSKNV TIETPDYYTK
LVIRPTQRSD SGEYLVTATN SSGKDSVLIN VVITDKPTPP KGPLQISDVH KEGCHLKWKR
PIDDGGTPIE YFQIDKLDSE TGCWVPCCRS TEPQVDVSGL TPGNEYRFRV SAVNSEGESL
PLLGEDAVVA KNPFDEPGKP ENLRATDWDK DHIDLAWTPP LADGGSPIIG FIIEKKDKYG
KWEKAVEVPA NQYEARVPDL TEGQAYEFRV SAVNAAGPGE PSDATHSLTA KSRNKPPVID
RSNLIEVRIK AGQGFGFDCK VSGEPAPKTK WLLKNKEIHT KENLKITHID YNTKLKVNGA
TRSDSGLYTV EAENENGKDS ANVKVTVIDK PSPPNGPLKV TDVAAEGCTL HWNPPDDDGG
QPIDSYSLEK LDEVTGRWIP AGETDSPITN IRIKGLTPGH KYKFRVRAKN RQGVSDPLTT
PHVIEAKNPY DEPTKPGIPI ITDFDKDFVD LEWTRPDSDG GSPITGYIIE KRDKYSPNFE
QIVEINGDIT NGHVPGLIEG VKYEFRVRAV NKAGLGTPSD STEPHLARSK NLPPNIDRNF
MTDIKIKAGN VFEFNVPVSG EPIPSKEWSH DDSMVINTDR VKITNYNDRT KLRTIDAKRS
DTGSYTLVAR NINGVDKHTV KLIVLDIPTA PEGPLRHNDV SKSSAMLSWR PPRDDGGSEI
THYVVEKMDN EAMRWIPVGE SSSTEIRADN LIENHEYNFR VRAVNKQGQS QPLVTSQLIT
AKDPYSHPDK PGQPIAVDWG KDYVQLEWTA PKKDNGAPIS SFIVEKRPKF GLWERALMVP
SNELTAYIPE LTDGGEYEFR IIAVNRAGPS DPSDPSTPII CKPRFLAPYF DKNSLNDITV
HAGKRLGWNL PIEASPKPSI KWLHNGKETA STRGESSLFQ NELTFEIASA IRGDEGRYTL
ILKNEHGCFD ASAHVTVLDR PSPPKGPVDI TKITRDGCHL AWNVPEDDGG SPILHYVVEK
MDLSRGTWSD AGMSTHPVHD VSRLVHRKEY LFRVKAVNAV GESEPMEAAN SIIAKNEFDE
PDAPGKPNII DWDRDHVDLQ WAEPKNDGGA PLEEYIVQKK EKGYPYWTNV LHVPPNQNNA
KVSELTEGQE YEFRVIAVNQ AGQSEPSEPS DLIKAKARYL APKILSPLRE IRIKAGLIFH
IDIDFIGEPA PEAIWTHNNN PLISNDKSTI TSIGHHTVVH TVNCQRTNSG IYHLLLRNDS
GIDEGSFELI VLDRPGPPDG PMQFEEITAN SVTVSWKPPK DNGGSEISSY IIEKRDLTHG
GGWVPAVNYV NAKYNHAVVP RLLEGTKYEF RVMAENLQGR SDPLTSDHPI IAKNQYTVPG
IPGKPEIADS DKDHISIKWK QPISNGGNSI IGYDIERRDV NTGRWIKING QPIPITEYQD
DRVSTNHQYQ YRVSAINAAG NSKPSEPSSI FHARPLREKP KLYLDGLVGK RLKVRAGEPV
NITIPISGAP TPTIEWKKDS QNLAEGKRVS SDTNSERSVF RIDDSRRQDS GKYSIIASND
FGIDKADIEI IVVDKPTPPE GPLCYTKTAP DHISLQWNPP KDDGGSEITG YVIEFSEFGT
DDWKPVPGYC PKTNYTVKGL LEGRKYIFRV RAENIYGSSD ALEGNPVISK SPFDPPGPPS
QPSITAYSPN SASLEWHPPD YCGGKPISGY IVERRERGGE WIKCNNYPTP NASYTVPDLR
DGVRYEFRVT AVNEAGPGQP SKPSDSVTAK LQCYCPDPPE PPKPDRISKD SVTLSWRPPR
NDGKSKIKGY YVEMRPKNGN DWKPVNELPI NSTVYVVPHL KEGEEYLFRV IAENDVGRSS
PSKPSQPIMI EEQPNKPSME LGSVRDIVCR AGDDFSIHVP YMAFPKPNAS WYSNDTILDD
DNRVHQHLTD DAASIVVKNS NRCDSGQYRL QLKNPSGFDT ATINVKVLDR PGPPSNLRAD
EFSGDSLTLY WNPPKDDGGS PIQNYIIEKK EAHSPTWNKV SSYCTVPFVR IRNLTINKEY
DFRVIAENKY GQSDSANTSE PIKARHPFDV PNAPGIPRGI DSSEDSITIS WSKPKHDGGS
PISGYIIEKR LLSDDKWTKA VHALCPDLTC KIPSLIENAE YEFRVAAVNA AGQSAFSASS
DLIFCRRPPN APKITSDLSI RDMTVIAGEE FHITVPYNAN PRPTPSWTLN GIDVAPNDRV
HFNTDDYISV YYNKFAKRCE TGAYTITLTN TKGADTASCH ITVVDRPAPP QGPLNAYDIT
PDNCTLAWKT PLDDGGSPIT NYVVEKLDPS GTWVKVSSFV RNTHYDVMGL EPQHKYHFRV
KAENQYGLSD PLVLSDPIVA KHQFTVPDEP GQPKVIDWDS GNVTLIWTRP TSDGGSRIQG
YQIEYRDIVN DSSWNTYDFL IKDTKYQLYN LANGTEYEFR IKAKNAAGLS KPSPPSLRFK
LKGKVSAPSP PETPQVTKVG KNYVDLKWEK PLRDGGSRIT NYVIERRDIG GALWVKCNDF
NVLDTEYTVT SLIEMGDYEF RIFAVNSAGR SEPSLCTMPV KVCEVIGGEK PEWITRLQNR
VVPHGKDCTL KCEAIGKPSP ISRWLRNGKE IQMGVSRFSC DSIDGVYRLH ISNVQAGDEG
NYTCEATNSL GFVHTTGFLK IGSPPIINKC PKELYLPEGD NTKIKIYYSG DQPLSVKITK
NNEVISDDND ESHFKFTIFD EYAALFIRDI VKNDAGLYQI EFTNDSGSAI GQFDVRITGI
PSSPTGPMGV SNINKHSCIV TWRQPAHDGG LRVTHYIVER KDVASPHWIT VSSTCKDTSF
NVQGLIENQE YIFRVMAVNE NGMGPPLEGL NPIRAKAPID PPSPPGIPQI LEIGGDFVHL
EWTKPESDGG SHIQGYWIDK REAGSDTWQR VNVTICSATQ INCPHLIETR QYEFQVFAQN
AAGISKASSA SQTVKIVDPK AASPPFVVKP LRDANCIQNH NAQFSCTISG IPRPTITWYK
GAREITNGAR YHIYSEGDNH FLSINDIFGE DADEYVCRAV NKAGAKSTRA ALVIMTAPKL
NVPPRFRDTA YFDKGENVVI KIPFTGFPKP RINWVKEGEN IESGGHYAVE VKERHAVLII
RDGSRLDSGP YRITAENELG SDTAIVQVQI SDRPDPPRFP LIENIGTDSL SLSWKSPVWD
GGSDITNYYV ERREHPLASW IRVGNTRFTL MAVGGLNAGK EYDFRIFADN VYGRSEPSNT
STLIKTKEAI KKKPTERKWE LDANGKKVRG KADGQIKDYD SYVFDIYSKF VPQPVEISQQ
SVYDKYDILE EIGTGAFGVV HRCRERSTGN IFAAKFIPVS HLIERDLIRR EIDVMNQLHH
QKLINLHDAF DDDDEMVLIL EFLSGGELFE RITVEGYVMT EAEVINYMRQ ICEGLKHMHE
RNIIHLDIKP ENIMCQTRSS TNVKLIDFGL ATRLDPNEVV KITTGTAEFA APEIVNREPV
GFYTDMWSTG VLAYVLLSGL SPFAGDNDVQ TLKNVKACEW DFDEQSFNNI SDDGKDFIRK
LLVANKEKRM TAHECLLHPW LTGDHSNMTQ AITRDRYLAY REKIRRKFED FEKYLLPIGR
LSEYSSLRKL LMEKYKIHDT VFDRRQAAPR FVIRPSSQFC YEGQSVKFYC RCIAIATPTL
TWTHNNIELR QSVKFMKRYS GDDYYFIINR VKLDDRGEYI IRADNHYGSR EEVVFLNVQP
LPKEQPRYRT ESTPIRRRDP LPYTFWQEES ESAPSFTFLL RPRVMQARDT CKLLCCLSGK
PVPSVKWYKD GRELSKYEYA MTHSDGVVTM EIIDCKPSDS GKYICKATNC HGFDETECVV
IVEGEWVTPE QAELAHNFLY SGDRKYIEQP LKPAPPQIVT SRQLTSTSMQ ETSETKNDEN
SNQSNLSNKK KYAASSLKAP GSPSRSRSAT KELILPPDDS LMFKPEFIVP LHDLNIHDGE
QLVLSCHVKG DPEPQITWSK NGKSISSSDI IDLKYRNGVA TLTINEVFPE DEGIFTCTAT
NSISAVETKC KLTIKALGKN ISNLRVASKD NAPKVVSHLE SRYVKDGDAV TLACRIIGAE
HFDVVWLHNN KEIKPSKDFQ YSKEANIYRL QIAEIFPEDG GTYTCEAFND VGESFSSCTI
NVSVPGDEPK HPAFVRFPIS VSIQEGENVI FDCELDSEIL NLIWVKDGKP IDETLSRYSF
TKENNIYSFS VSKCNMDDVG QYQAKAIARK GESICAFSVN IYNSEL
//
