ID A0A0P8Y6Y0_DROAN Unreviewed; 8836 AA.
AC A0A0P8Y6Y0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Uncharacterized protein, isoform AI {ECO:0000313|EMBL:KPU77157.1};
GN Name=Dana\GF11157 {ECO:0000313|EMBL:KPU77157.1};
GN Synonyms=dana_GLEANR_11226 {ECO:0000313|EMBL:KPU77157.1};
GN ORFNames=GF11157 {ECO:0000313|EMBL:KPU77157.1};
OS Drosophila ananassae (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7217 {ECO:0000313|EMBL:KPU77157.1, ECO:0000313|Proteomes:UP000007801};
RN [1] {ECO:0000313|EMBL:KPU77157.1, ECO:0000313|Proteomes:UP000007801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 14024-0371.13 {ECO:0000313|Proteomes:UP000007801};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
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DR EMBL; CH902619; KPU77157.1; -; Genomic_DNA.
DR RefSeq; XP_014762578.1; XM_014907092.1.
DR EnsemblMetazoa; FBtr0389088; FBpp0348743; FBgn0088197.
DR Proteomes; UP000007801; Unassembled WGS sequence.
DR GO; GO:0042995; C:cell projection; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR CDD; cd21188; CH_PLEC-like_rpt1; 1.
DR CDD; cd21189; CH_PLEC-like_rpt2; 1.
DR CDD; cd00051; EFh; 1.
DR CDD; cd00176; SPEC; 17.
DR Gene3D; 1.20.58.60; -; 30.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.30.920.20; Gas2-like domain; 1.
DR Gene3D; 3.90.1290.10; Plakin repeat; 11.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR041615; Desmoplakin_SH3.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR003108; GAR_dom.
DR InterPro; IPR036534; GAR_dom_sf.
DR InterPro; IPR049538; PCN-like_spectrin-like_rpt.
DR InterPro; IPR043197; Plakin.
DR InterPro; IPR035915; Plakin_repeat_sf.
DR InterPro; IPR001101; Plectin_repeat.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF02187; GAS2; 1.
DR Pfam; PF00681; Plectin; 1.
DR Pfam; PF17902; SH3_10; 1.
DR Pfam; PF00435; Spectrin; 17.
DR Pfam; PF21020; Spectrin_4; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM00054; EFh; 2.
DR SMART; SM00243; GAS2; 1.
DR SMART; SM00250; PLEC; 31.
DR SMART; SM00150; SPEC; 36.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF143575; GAS2 domain-like; 1.
DR SUPFAM; SSF75399; Plakin repeat; 14.
DR SUPFAM; SSF46966; Spectrin repeat; 30.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
DR PROSITE; PS51460; GAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000007801};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 160..289
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 301..406
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 960..1018
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 8395..8430
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 8431..8466
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 8471..8543
FT /note="GAR"
FT /evidence="ECO:0000259|PROSITE:PS51460"
FT REGION 1..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 97..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2857..2882
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2908..2933
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2973..3007
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3117..3246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3285..3309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3333..3429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5594..5655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 8242..8335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 8570..8603
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 8615..8836
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 517..601
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1100..1127
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5270..5301
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5416..5443
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5676..5739
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5975..6002
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 6299..6435
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 6519..6546
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 6839..6866
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 7574..7639
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 22..41
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..147
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2986..3007
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3121..3154
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3285..3301
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3333..3352
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3354..3385
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3387..3410
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5627..5655
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8272..8286
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8287..8308
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8309..8323
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8570..8600
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8618..8643
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8651..8760
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8770..8823
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 8836 AA; 994294 MW; 80D4BADE3771815C CRC64;
MTSHSYYKDR LGFDPNEQQN EHSHLHSSNS NSNSNSMKRS SSRQTTHHHQ SYHHATTSSS
QSPARISVSP GGNPGNNGTL EYHQVQREQR DRELYSNNHH HSHHHQQQSH HHRHSSGNTS
SPLYESSPAA PKKAKHSSTQ PQPQGGYEDA LTQFKDERDA IQKKTFTKWV NKHLKKHWKY
AKTYTMLHVC VTTNGIPCCS QSANRRVVDL FEDLRDGHNL LSLLEVLSGE HLPREKGKMR
FHMLQNAQMA LDFLRYKKIK LVNIRAEDIV DGNPKLTLGL IWTIILHFQI SDIVVGKEDN
VSAREALLRW ARRSTARYPG VRVNDFTSSW RDGLAFSALV HRNRPDLLDW RKARNDRPRD
RLETAFHIVE KEYGVTRLLD PEDVDTNEPD EKSLITYISS LYDVFPEPPS IHPLFDMESQ
RRVHEYRDLA QQFIYWCREK TAYLQERSFP PTLIEMKRLL SDLQRFRSEE VSARKREKSK
LIQIYKELER YFETVGEVDV EAELRPDAIE KAWYRMNTAL QDREVILQQE IERLERLQRL
ADKVQREIKH VDQKLTDLET RIVEEGRRIE RLHPVDAKSI VEALETEIRH LEEPIQDMNQ
DCHVLNEGRY PHVSELHKKV NKLHQRWAQL RTNFHTNLVQ KLSGLKYPVH ETTVTRQTRM
VVESRQIDTN PHFRDLQEHI EWCQNKLKQL LAADYGSDLP SVKEELDRQQ HEHKIIDQFH
SKILNDERQQ TKFSGDELAL YQQRLNQLQK VYAELLSTST KRLSDLDSLQ HFLGQASAEL
QWLNEKEQVE ISRDWADKQL DLPSVHRYYE RAFGNGDENL MSELEKREMH FATILDRGEA
LLNQQHPASK CIEAHLTALQ QQWAWLLQLT LCLEVHLKHA TEYHQFFGEI KDAEQWLAKR
DEILNSKFSQ SDFGLDQGET LLRGMQDLRE ELNAFGETVA TLQRRAQTVV PLNKRRQPVN
RQGPVQAICA YKQQGQLQIE KGETVTLLDN SGRVKWRVRT SKGQEGSIPG ACLLLPPPDQ
EAIDAAERLK RLFDRSVALW QKKHLRLRQN MIFATIRVVK GWDFDQFLAM GPEQRTAIRR
ALNDDADKLL SEGDPNDPQL RRLRREMDEV NRLFDEFEKR ARAEEESKQA SRIFTEECIA
IKSKLEDMAR ELDQIILAPL PRDLDSLEHV LEIHADYERR LHLLEPELKH LQETFRTIAL
KTPVLKKSLD NLMELWKELN TQSGLHKDRL KLLEASLAGL EDNEHVISEL ENELAKHQDL
PSTAEGLQQV FKQLTHMQDV ITQQQPQMDK MNDAADQLGR MGVPTKVLGD LKRLHSNVER
LNTRWSAVCN QLAERMRSCE TAIGLMKNLQ SSVQVEESWV DGTTERLSAM PTATSAYELD
CIQEAPTKPT KQTNQIADYD FVELNETKAL DMPQHRSGRK TTKSKTQTTT VQVAEESDYD
FAFEFQQYAE SLQKPLKTFR VDFSAGSVPT GDGYAARPED LYTTTYSTTQ FSSTKTTKSS
TKSVYSSDGL DAASQEVITS NLPPSQIQFN EIRTLKRSQQ LGGNSVLDIA GIRDPRTGRV
LTIGEAIQLR ILDVRTGEML VGDRRISLEQ AAEQGLIDAQ LARQLLQPGA GRDASGRELS
LLEVIQREIN EAESGYETAE KRIKVNSTVT VESTGSPENP RNIADAITAG SVDTKTGLYR
VKSGQTISLA EAYERGYLIR HESVTIKSNA LCLSDAIAHG LVDGAGWIAD RNSGDKFRLD
SAIANQLIDA GVREVVDAKR DTKITLQEAL QSGVLNAKTG RYVNEVTKEK LTFAEARNRQ
LIVKPYTLKD ICDLNLLDKQ AQITSPMRRE KLSIMQAIEA GVLDGNNLKC ITKRKGELVT
LQEAIADGIV LPAECKYRDF MTGELISIPE AVERGLISSV AQRSIFDIDG FKDLRSSDYV
SFNVALSRDL LRRKSTGFAL ETGRDSLVPL EVAVGEGLVR QEVYEMFNRG IGVQNASGQE
LSVFDLVYHN LIDPKTGYLL DPKTGETVPL DTAIERKFIT AEGALLLSSL LNITLTTETV
TRTINRYVTI RAGSQEPGDQ VLLTFTEAVR QGFIDEERQL FKDPKTGNIY SVQQALNYGL
LVPDSNQTVP EPTNRKKTKS TITIVTKQII PEAEPIKLNT QHTKYVEKSV EIPISQELIK
PQRVVSDFIN MEKSSYIEQN VTERQIMELP PGGWRLKDAI EQRIFNPDTG VFHVQGTDRL
VNFEECINKQ IINNLSVSII DPSTGDKISV QSAFERDILD SYGNYTNSRK QVLGMRSAID
EGKIILETVP ATRGSSQKTI LRITRVNNMP DVLEVSTPLK DAPPKFVEVS TCQRELASPE
PLQIAPGAIY DPSTALVIFT QSGETENIFD AARQGLIDEQ LIKIVDPRTK QPISVTEAIA
RSIYDPKTET ILDAEGQPVD LITATKLGLL SVVGAPLVAA EGALRTVRFV TDPRTGEQIP
VEVAYERGIV SRDQLQRGRS FDSEPSTTTV EEKVVVLQRM RKIILKPKDA LRKGIIDEET
CKILEDTNNF TNPQGEVVNI TEALNTGMID GRRGKIIDPQ SNRVLNLRQA VEQKILDPEQ
TNHILMPLAK SLSVPRLAAQ GLVDPKTQTI VHPESGYPLS IHEAIVCEVL DPHSTLRKPE
KCTLEAAIKK GIVDADESIF KYKNKNLNIS EAIEARLFDP SYDQQKSKVD IPPVGMIFPV
AVEKSLVEPS KRVVLHPSTK NALPIKQAID ENFIMSIPYA PKKDAIEVVA AMERDLIDVA
AQTITVPTTG ERLPLRQAME NGVLVVKQLS DFVVTQKPIP KTEIMETVRA VHTVTTKTIE
LMQGYVLISN NEVQNVNTGE VVSLEEAKEL GILREESTTR ETKAAAGESP EAVQNLPTSS
DQTVVVEERT QTVVVSSDTH KQEMQVISTT QSTKENPAIP TVSEAETKVG KEPSKTLQNV
KDAAKMGALG VIAAPVLAGG ALVSGVKSLI KSVKSPAEDA KTTTQKPEKP QSSFIEQERR
NVPEPQQVPS EVDNLLNETE NFISSTTANF IINEQQQEKP QEVSRQEVES TNTLTTTTVT
TITTSKTTTE TGDAEPVVVE DVKTTTTVET TPVEPEIAKK PEDKPVDVQV TETITTVTRE
ETISEPEKPT TKEPTPEKIV EKKPVEKPAK KETTPAPVTK ETTPAPVTKE PTPEPIQKEK
TPEPAPREAA QVPTKPEPQP RTAVKEEVPA FEPPFTAPLA PFEEPKAETK ITEVTTEVQE
PVSSTETITT ITTTVTTIDQ QPKEVTEVDK SEPAKITEVE VEKPAVQEPI KDDKPSEILD
EVSEEPTSSI VVEERVITVE EPTITESTVT TTITTTTTTT SSEEQQPQET VVTEIVKEEP
KKDTPQPEKT VVTEELVKEE PAKDASQPIT EPTQTTETVT TTTTIIQEEK PQQPGDLEQI
VQPPTSTNKH QSVVDFIQAE KNTQPSEGSK VLQNVKDAAK LGALAIVGAP VLAGKALVDA
LTSDKATKTG QPTTHVVTEI VEELPADISR TTSTIVTKVT TTTTTTTTTG EGSPEDEARD
VVELPISSAE PTIKREVPKT LPIGDAISQK LISPDECQVI VDGEQQSQTV STLLKEEQLS
PLDEVQIIDD KLIILQQISY LVDVDTELTP EKLSELNIYD PENQYFIDPT TGQKISFQTL
VFDMNIFNPE TILVKNFSTG KYETLTAALE RPLLDRHTGH MVDPKTGKKI PFFECIERQW
IIRADPEEQK PTGMENVTID PQTGQVILDD GRVCSIVEAI NSGKLDIQSI SVRDPVSGEV
IPLRMAIELG VVDMQAGTVI DIQTLKEIPM ELAFQLGFLV PGARKPISLE AAVRKGLYDP
ETGKLFDSES QNQVDVQKSI EIGLVDPKIS LIVDTVTKKE VKLDCAIEDE LVVPSTGQIK
DNKNNTLVPF DVGVQQRLVK TDSVTWSLPE VLQREYYTPS TGKVLNPVTG EEILLQQAIE
MGFVELDTTL VKDADHDKIV PGKEAAKVGL LDTVRGTLSS PNISLDEAFV KGYLISTKKP
LSLVDCLLRG LYDPSTAKFT IDDKQLDLKS AIAQKLINPE ELVLLDPKTE SIISLTEAIA
KGYLDPIGGY VINPYTSTKL SLHEALENRI LIPPKRKRSL PDAVYRGLYD PKTGQFSNTV
TREKLTTERA IRRGILDPDS TVVNVGSGQI IPFGVATETG IVDSRQGTVK DQDDKSIDFK
EAFDRGVLVE AKKPLRLIEA VVKNVYDEVD GHFVDPKSGE KLNFAEALNT NLLDEHSVQI
RDFKTGLYKQ LNLTHAKDSG VIDAQNSKLL YNNQTMTLKH AFDIGILMDV NAPISIQRAI
HQGLFDDKTG KLSDPRSGRQ ITLLEGMRSF VINPHLSCYF DEQTETMYSL SETCRNGIIN
RREGVFREPG SSSFVPLGEA LSLGLIVDIE NAGFGLYELL SMGFYDTPTR KVLHPVTNRK
LNLNEACVED VVSLSSSLVK HHETGKYLRL ANAIKEQLID DNRGCYNLGN EQLDLQAARA
RGFIVSNRRL LSLELVLRQQ LYRPETGKFC DPTTGEYLDL IEAIHSGFID PATTVFKNQL
TGKELPLGEA IENGDIDVSK GRVFDPKSKS AYNYDVALAR GILVTVARPL TDRSEVVRRQ
DSVELLGQTP VSVVISKPRE MSLEEAIRYN IIDPKTALVR DFDSFKFLPY SVAVERGLVD
TTKRTLVDPK ALYFAFDPTL IVYVREPITF DQAAESKCLD LQTGILTYVP VSSATGNESA
PAGDDSANDS LTVIETPKVY TLKEAASAGV VDPDSALVKD LAKAKLVRLP EAFRKGLMDA
NKANVLNTQT SKLCTLQEAY ESGLICTPKR SFGLLEAITF NLYNPTNGCL VDPFQMHPDI
IRRRKFTLAE AIGSGLVDPS STVVRDPSSG VIVPLTAAIG SGLIDAAEGR LTDASDPKNN
IDLVKAAEKG LLLPAEQRQA VFEKFNMCEE NVNDLLKWVT TVEQKISSVG GPREKIDELR
NQINALKQIK DEIESQQRPV ATCLEQIRQI VLTGGDVLSA PEVTTLENSG RELRSRVDRV
NDRTVRLLRR LEAGRDELTK LRSELDVFSD WLQVARRTLE DKERSLSDLT RLPSQADSVR
EFVSDVIGHQ ADLRFITMAA QKFVDESKEF LAILNDFRTS LPERLPHVEP LSSAESPIRQ
EVSLVSAQYK DLLNRVNALQ DRVSGLGGRQ REYQDALDKA NEWLRSIAPR VSRIIAEPIA
GDPKGVQDQM NEAKALHNEL LSSGRLVDNA QQALDNLLRS LGGQLSPMEI NQLELPIADL
KNNYQQLLDN LGEHCKNLDK TLVQSQGVQD ALDSLVGWVN QAEDKFKLNL RPASLIKERL
QEQIREHKVL LADLQSHQAS IDSVQISAKH LLASASNARI AKKVESNLND VTGKFEKLYE
KANKRGEFLD DVYNRLGRYL DDISNVEQRM ASLQEALDSR ETSLLSTEEL ARRMNDLSRE
KDHLAPQFED CVRNGKDLIG LRDVTDTGVL RDRIKALESQ WRNINISIDE RAKLSKQKAE
QQLAYEGLKD QVLSWLASTE ARVNGLPPVA IDLDRIKQQH DELKPICKDY RDYAPTIDKI
NDIGAQYDAL IRPESPARKR STYSPIKRAS PLRRMSGDAR SPSPTKGGIL SPLSTGSSGF
GSRRSSQDGF QLSELSPVQQ QLSEINNRYG LIGVRLNDRQ HELDNLSEEL RKQYDNLKGL
AQFLERIQRQ VPKESVSNKD EAERCIKQAR KILEDMYEKQ SLLDTTKAQI KDILRRKSDV
PGAEQLRLEN ENIQEKWKNL NDICKNRIAF SEKLRDFLDT HGNLKSWLDS KERMLTVLGP
ISSDPRMVQS QVQQVQVLRE EFRTQQPQLK HFQELGHDVV DHLAGTPDAQ AVEVKLKDIL
GKWEDLVGKL DDRANSLGGA ADSSKEFDAA VNRLREALQN ISDNLDALPT DGDHQENLRK
IENLERQLEG QRPLLADVEQ SAATLCNILG DPASRADVNS RVAALEKQYL ALQKKLDTKK
AETEASLRDG RHFAENCSKT LGWLGGELSN LTDRLLVSAH KPTLQHQIDT HEPIYREVMA
REHEVIMLIN KGKDLSDRQQ DRGVKRDLDR IQQQWEKLRR EAVDRHTRLQ TCMEHCKKYS
QTSEQFLAWL RTAEDKLSDL TPGVLSKAKL ETRLRDLQTF RSEVWKHSGE FENTKGLGET
FLTSCDIDKE PIKAELQDIR DRWERLNNDL IARAHEIENC SRRLGDFNDE LRNLDHSLGR
CEDRLAAHDA LGGAAKDPKL LERVKAIREE LTNLSKPLQS LKALAKDISA EARAAGGDAD
HLTSEVDGLA DRMSELQGRL DDRCGELQSA ATAVSQFNEQ MKSLGIDLND LETEIEKLSP
PAREIKIVQQ QLDDVGKIQH KLDRLVGRLE DAERAADVLV DAGFAADTTQ TREQISTLRK
TLGRLDNRVR DHEDNLQATL KALREFYDNQ STTLDDIQDV SEEFKRMKPV GSELDQIRRQ
QEDFRNFRER KVEPLAVNVD KVNVAGRDLV RSAGSGVSTT AIEKDLEKLN DRWNDLKERM
NERDRRLDVA LLQSGKFQEA LAGLSKWLSD TEEMVANQKP PSSDYKVVKA QLQEQKFLKK
MLLDRQNSMG SLANLGKEVA NHCEPAERAS IEKQLNDLMK RFDALTDGAE QRELDLEEAM
EVAKRFHDKI SPLELWLDNT ERAVKSMELI PTDEEKIQQR IREHDRLHDE ILGKKPDFTD
LADVAAQLMH LVSDEEAVNL GEKVRGVTER YTGLVDASDN IGALLSESRQ GLRHLVLSYQ
DLVAWMESME AELKRFKSVP VYAEKLLEQM DHLLELNENI AGHASNVEST VESGAELMKH
ISNDEAIQLK DKLDSLQRRY GDLTNRGGDL LKSAQNALPL VQQFHEAHNR LVEWMQSAEA
ALAPSEPRQS DVLRLEGELA DMRPILDTIN LIGPQLCQLS PGEGAATIES IVTRDNRRFD
SIVEQIQRKA ERLHLSNQRA KEVTGDIDEL LEWFREMDTT LREADPPAME PKLVRAQLQE
HRSINDDISS QKGRVRDVTA ASKKVLRESP QSENTATLRE KLDDLKEIVD TVAQLCSERL
GILEQALPLS EHFADSHQGL TAWLDDMEQQ ISRLSMPALR PDQITLQQDK NERLLQSIAE
HKPLLDKLNK TGEALGALVA DEDSAKINEI LDTDNARYAA LRLELRERQQ ALESALQESS
QFSDKLEGML RALANTVDQV NQLDPLSALP QKIREQIEDN DALMDDLDKR QDAFSAVQRA
ANDVIAKAGN KSDPAVRDIK AKLEKLNNLW NDVQNATKKR GSSLDDILSV AEPFWKQLNS
VMKTLKDLEE TLSCQEPPAA QPQDIKKQQV ALQEIRHEID QTKPEVEQVR RHGSNLMNMC
GEPDKPEVKK HIEDLDNAWD NITALYAKRE ENLIDAMEKA MEFHETLQNL LKFLTKAEDK
FAHLGAVGSD IDAVKRQIEQ LKSFKDEVDP HMVEVEALNR GLQRQAVELT ERTSPEQAAS
IREPLSVVNR RWEALLRGMV ERQKQLEHAL LHLGQFQHAL NELLVWINKT DGTLDQLKPI
PGDPQLLEVE LAKLKVLAND IQAHQNSVDT LNDAGRQLIE TEKGSLEAST TQEKLRKLNN
EWKQLLQKAS DRQHELEEAL REAHGYIAEV QDILGWLGDV DAVIGASKPV GGLPETATEQ
LERFMEVYNE LEENRPKVET IQAQGQEYIK RQNQMKVSSS NLQHTLRTLK QRWDAVVSRA
SDKKIKLEIA LKEATEFHDT LQAFVEWLTQ AEKLLSNAEP VSRVLETIQA QMEEHKVLQK
DVSTHREAML LLDKKGTHLK YFSQKQDVIL IKNLLVSVQH RWERVVSKAA ERTRALDHGY
KEAREFNDAW SGMMQYLQET EQVLDQIIEE ATASKEPQKI KKYIGKLKET HRQLGAKQSV
YDGTMRTGKN LMERAPKGDR PVLDKMLLEL KEQWTRVWSK SIERQRKLEE ALLLSGQFSD
ALGELLDWLK KAKSRLNENG PVHGDLETVQ GLCEHHKHIE QDLQKRAAQM QGVLKTGRDL
ERSGNNPEVG RQLDEMQSIW EEVKNAVAKR GDRLQVALVD AEKLNARVQA LFDWLDHAEH
KLRYAKNAPD DEKVSREMMD IHMEFMKDLR VREREKTETF EYAEDIIGKA YPDAIPIIKN
WLSIIQQRWE EVRQWAINRE SKLEQHLQSL KDLDDTIEEL LAWLSGLEGT LLNLKHERLP
DEIPPVEKLI EDHKEFMENT ARRQNEVDRA CKPRQLPPGA RKPSRSGKTP VRGSSHDLRE
TSPDGTLRRQ SFKGSRDQGL NARKGSRVTP TRDTPDRDRL PHYGPRFSPS TAGPELEFRS
PRAKLLWTKW RDVWMLSWER QRLLYDHLLY LKDVERARNF SWDDWRKRFL KYMNHKKSRL
TDLFRKMDKD NNGMIPRDVF IDGILNTKFD TSGLEMKAVA DLFDRNGEGL IDWQEFIAAL
RPDWQERKPA TDSDKIHDEV KRLVMLCTCR QKFRVFQVGE GKYRFGDSQK LRLVRILRST
VMVRVGGGWV ALDEFLQKND PCRAKGRTNI ELREQFILAD GVSQSMAAFT PRRSTPNAAA
TASSSPNAQN GGSSNLPPYM SGQGPIIKVR ERSVRSIPMS RPSRSSLSAS TPDSLSDNEG
SHGGPSGRYT PRKVTYTSTR TGLTPGGSRA GSKPNSRPLS RQGSKPPSRQ GSTLSLDSTD
DHTPSRIPQR KPSTASTTSG TTPRPARLSV TSTTPGSRLN GTSTITRKTA SGSASPAPTS
RPSRIPIKIP SFDSKSTSPT SSTTNPTSLG RNISGSSTPS GMQTPRKSSA EPTFSSTMRR
TSRGTTPTEK REPFRL
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