ID A0A0P9E7L9_9ARCH Unreviewed; 786 AA.
AC A0A0P9E7L9;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Putative tRNA pseudouridine synthase B {ECO:0000313|EMBL:KPV62808.1};
GN Name=truB_1 {ECO:0000313|EMBL:KPV62808.1};
GN ORFNames=AOA66_1207 {ECO:0000313|EMBL:KPV62808.1};
OS Candidatus Bathyarchaeota archaeon BA2.
OC Archaea; Candidatus Bathyarchaeota.
OX NCBI_TaxID=1700836 {ECO:0000313|EMBL:KPV62808.1, ECO:0000313|Proteomes:UP000050284};
RN [1] {ECO:0000313|EMBL:KPV62808.1, ECO:0000313|Proteomes:UP000050284}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BA2 {ECO:0000313|EMBL:KPV62808.1};
RX PubMed=26494757; DOI=10.1126/science.aac7745;
RA Evans P.N., Parks D.H., Chadwick G.L., Robbins S.J., Orphan V.J.,
RA Golding S.D., Tyson G.W.;
RT "Methane metabolism in the archaeal phylum Bathyarchaeota revealed by
RT genome-centric metagenomics.";
RL Science 350:434-438(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPV62808.1}.
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DR EMBL; LIHK01000036; KPV62808.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P9E7L9; -.
DR STRING; 1700836.AOA66_1207; -.
DR KEGG; barb:AOA66_1207; -.
DR PATRIC; fig|1700836.3.peg.1684; -.
DR Proteomes; UP000050284; Unassembled WGS sequence.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
DR GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd00081; Hint; 1.
DR CDD; cd21148; PUA_Cbf5; 1.
DR Gene3D; 2.170.16.10; Hedgehog/Intein (Hint) domain; 1.
DR Gene3D; 3.10.28.10; Homing endonucleases; 1.
DR Gene3D; 3.30.2350.10; Pseudouridine synthase; 2.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR InterPro; IPR003586; Hint_dom_C.
DR InterPro; IPR003587; Hint_dom_N.
DR InterPro; IPR036844; Hint_dom_sf.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR006142; INTEIN.
DR InterPro; IPR030934; Intein_C.
DR InterPro; IPR004042; Intein_endonuc.
DR InterPro; IPR006141; Intein_N.
DR InterPro; IPR004860; LAGLIDADG_2.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR002501; PsdUridine_synth_N.
DR InterPro; IPR002478; PUA.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR004802; tRNA_PsdUridine_synth_B_fam.
DR InterPro; IPR032819; TruB_C.
DR InterPro; IPR004521; Uncharacterised_CHP00451.
DR NCBIfam; TIGR01443; intein_Cterm; 1.
DR NCBIfam; TIGR01445; intein_Nterm; 1.
DR NCBIfam; TIGR00451; unchar_dom_2; 1.
DR PANTHER; PTHR23127; CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5; 1.
DR PANTHER; PTHR23127:SF0; H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1; 1.
DR Pfam; PF14890; Intein_splicing; 1.
DR Pfam; PF14528; LAGLIDADG_3; 1.
DR Pfam; PF01472; PUA; 1.
DR Pfam; PF16198; TruB_C_2; 1.
DR Pfam; PF01509; TruB_N; 1.
DR PRINTS; PR00379; INTEIN.
DR SMART; SM00305; HintC; 1.
DR SMART; SM00306; HintN; 1.
DR SMART; SM00359; PUA; 1.
DR SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 1.
DR SUPFAM; SSF55608; Homing endonucleases; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 2.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR PROSITE; PS50818; INTEIN_C_TER; 1.
DR PROSITE; PS50819; INTEIN_ENDONUCLEASE; 1.
DR PROSITE; PS50817; INTEIN_N_TER; 1.
DR PROSITE; PS50890; PUA; 1.
PE 4: Predicted;
KW Autocatalytic cleavage {ECO:0000256|ARBA:ARBA00022813};
KW Protein splicing {ECO:0000256|ARBA:ARBA00023000}.
FT DOMAIN 310..455
FT /note="DOD-type homing endonuclease"
FT /evidence="ECO:0000259|PROSITE:PS50819"
FT DOMAIN 609..632
FT /note="Intein C-terminal splicing"
FT /evidence="ECO:0000259|PROSITE:PS50818"
SQ SEQUENCE 786 AA; 90037 MW; 5022764EC922C7CD CRC64;
MTGVLPTALE EATKVVQALL LTGKEYVCVM KLHSQVSEDQ IKAVLGEFHG TIYQRPPVRA
SVKRRLRTRK IYYLDLLETD GRNVLFKVGC EAGTYVRKLC VPGDTEIIVY NGGLLKIKEL
DGKALNTLSK GLFTISMNNF KIEKAEIKKL YKLPAPNKLI RIVTESGIPI TVTPDHEILI
STINDPLWVP ACSLRVNDFI FSPRKIPIEG HYPYIVDLLD DEMYVMNQEI RNMCIKGIKD
RFGSIREMSR KLGIDRKTFY SHSKTGIRIK YVKSFCEWID AKKLISIIKT ERGRIIELYD
KRINNDWMYL LGLIASDGCV IHERKCIRPN RLKFHNPDQK LINTFVMSHK RLFPKIPLHI
KPLRNNMIEI DTHNPVLAGV AYSLGIRTPE KFMNLNGIFV LPEELIKAFL KGYFDGDGLA
FFGKKGKKTI TSIELCTGFQ LIAKRMHQLF KRLGIRSKIF QRKPAGRFRS SEGFAYSVRI
VDPIDKLRFI EEIGSNHPQK KECLRKIGKH FKKRKAKFLD HVPLHVNEMI MSLLTANHLA
PSCLRLGGNF ERVLKCKKAM TKYLLGRVIE CLSKFLKKCE IEPLLQMFHS DFFVEKVKKI
EEIEPEEGYV YDVTVENIHN FIPEGVMVVS NCYDLGEALG CGAHMQELRR TRVGPFVEDE
GLVTLHDVSY MFAQWQETRD ENLLRKFIYP MEKSLELFPK IYIRDSAVDA ICHGAHLAAP
GVLSLHTEIK PNDAVAVFTQ KGEVVALAKA LTSTEEILRM DHGLVAKIQR VLMPRGIYPK
MWRSGL
//
