ID A0A0Q2MJI6_MYCGO Unreviewed; 457 AA.
AC A0A0Q2MJI6;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=GntR family transcriptional regulator {ECO:0000313|EMBL:KQH79959.1};
GN ORFNames=AO501_22565 {ECO:0000313|EMBL:KQH79959.1};
OS Mycobacterium gordonae.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1778 {ECO:0000313|EMBL:KQH79959.1, ECO:0000313|Proteomes:UP000051677};
RN [1] {ECO:0000313|EMBL:KQH79959.1, ECO:0000313|Proteomes:UP000051677}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CTRI 14-8773 {ECO:0000313|EMBL:KQH79959.1,
RC ECO:0000313|Proteomes:UP000051677};
RA Ustinova V., Smirnova T., Blagodatskikh K., Varlamov D., Larionova E.,
RA Chernousova L.;
RT "Mycobacterium gordonae draft genome assembly.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQH79959.1}.
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DR EMBL; LKTM01000057; KQH79959.1; -; Genomic_DNA.
DR RefSeq; WP_055577244.1; NZ_LKTM01000057.1.
DR AlphaFoldDB; A0A0Q2MJI6; -.
DR STRING; 1778.A9W97_16915; -.
DR OrthoDB; 199743at2; -.
DR Proteomes; UP000051677; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000051677};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 11..79
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 457 AA; 49222 MW; 5E49D4006AE441C5 CRC64;
MDLHLELPPG RGRRAALESA LRQAIRDGRL APGQWLPSSR ALAAQFQMAR GTVVEVYSQL
AAEGYLRTRP GAATEVAHGP LMPPRVSAQG ATARVVADFR LGRPDLSMFP RQEWLRALRR
ALQVTAHAEL GPGDPRGSPR LRAVLADYLG RVRGVLTNSE HIVICSGFTQ GLRLVCDALA
AGSAGPTALE NPCLPDHRAI VEAAGLTVHS LDVDAGGARP DRWPSTSVAA VLTPAHQAPL
GMTLDAHRRT EFTRVAAARG TYLIEDDYDG EFRYDRHPVG ALQGLAPERV IYAGSASKSL
APGLRLGWLA VPPALVDEVV EAKRRADRGT DVLAQLALAE LIESGGLDRH VRRMRRRYRG
RRDALVETLD RYAPEVSVQG ISAGLHAVVS LPDERTEADA LNLARDRNLA LTGLAPFWHG
TARRSAGIVV GYGTPAEHEY AGALDHLGRL MRALTSS
//
