ID A0A0Q3PBX8_AMAAE Unreviewed; 2217 AA.
AC A0A0Q3PBX8;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=ATP-binding cassette sub-family A member 1 {ECO:0000313|EMBL:KQK73716.1};
GN ORFNames=AAES_164603 {ECO:0000313|EMBL:KQK73716.1};
OS Amazona aestiva (Blue-fronted Amazon parrot).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK73716.1, ECO:0000313|Proteomes:UP000051836};
RN [1] {ECO:0000313|EMBL:KQK73716.1, ECO:0000313|Proteomes:UP000051836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FVVF132 {ECO:0000313|EMBL:KQK73716.1};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQK73716.1}.
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DR EMBL; LMAW01003155; KQK73716.1; -; Genomic_DNA.
DR STRING; 12930.A0A0Q3PBX8; -.
DR Proteomes; UP000051836; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR PANTHER; PTHR19229:SF34; PHOSPHOLIPID-TRANSPORTING ATPASE ABCA1; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:KQK73716.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000051836};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 637..657
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 677..701
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 713..733
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 740..760
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 772..794
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1343..1364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1651..1673
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1693..1719
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1731..1750
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1762..1786
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1849..1871
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 896..1127
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1908..2131
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1282..1306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1282..1304
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2217 AA; 249201 MW; 2CD90E1DF2D36C77 CRC64;
MAFWTQLGLL LWKNFTYRRR QTFQLLIEVA WPLFIFFILI SVRLSYPPYE QHECHFPNKA
MPSAGTLPWI QGIICXANNP CFRYPTPGES PGIVGNFNAS IHCTIKFLEE GVXLEGSFDF
QQIALQSEFE NAQRDKKADL KLRDFLIDNE TFSDFLHHNV SMPSSAVGVL LNADVNLHQV
FLSGYRMRLR DLCNRSALSE XLTIQNQTVA MDSEAYICTL PKEKLHAAEQ AFRANLNPLK
PLQRLSFNSS LWDLSGXVEA LRESLQKLVK ELLSMKSWSD MRQEVMFLTN VNASNSSTQI
YQAVSRIVCG HPEGGGLKIK SLNWYEDNNY KALFGGNGTE DDVTNFYDNS TTPYCNELMK
NLESSPLSRI IWRALKPLLI GKILYTPDTP SVRKVMTEVN RTFQELGVFR DLGGIWEEIS
PKIWTFMESS QEMDLIRTLL KSKALWDLHL LASNWTVEDI ARFLSNHPED FETANDSVYT
WVDAFNETDR AIQTISRFME CVNLDKLEPV ATEVRLINKS LELLDERRFW AGVVFTEIAP
NSTELPQHVK YKIRMDIDNV ERTNKIKDGY WDPGPRADPF EDMRYIWGGF AYLQDVVEQA
IIRVQTGTEK TTGVYVQQMP YPCYVDDIFL RVMSRSMPLF MTLAWIYSVA VIIKGIVYEK
EARLKETMRI MGLDNGILWL SWFISSLIPL LMSAGLLVLI LKMGNLLPYS DPSVVFVFLS
IFGIVTILQC FLISTMFSRA NLAAACGGII YFTLYLPYVL CVAWQDYVSF SLKIFASLLS
PVAFGFGCEY FALFEEQGVG VQWDNFFESP LEEDGFSITT SAVMMMFDTF LYGVMTWYIE
SVFPGQYGIP RPWYFPFTKS YWFGEKPQER EHCYPDQKGP SEVCKEEEPT HLSLGVSIQN
LVKVYRDGKK VAVDGLTLNF YEGQITSFLG HNGAGKTTTM SILTGLFPPT SGTAFILGKD
IRSELSNIRQ NLGVCPQHNV XFDLLTVEEH IWFYARLKGL PEKKVKEEVE QMAVDVSLPH
KLKARTSKLS GGMQRKLSVA LAFVGGSKVV ILDEPTAGVD PYSRRGIWEL LLKYRQGRTI
ILSTHHMDEA DILGDRIAII SHGKLCCVGS SLFLKNQLGT GYYLTLVKKD VDSSLSSCRN
SSSTVSYLKK DDSVSQSSSD AGLGSDHESD TLTIDVSAIS NLITKHVPEA RLVEDIGHEL
TYVLPYKAAK EGAFVELFHE XDDRLADLGI SSYGISETTL EEIFLKVADD SGVDAETSDG
TLPARRNRRV FGDRQSCLRP FTEDDAFDPN DSDIDPESRE TDLLSGMDGK GSYQIKGWKL
TQQQFMALLW KRLLXAKRSR KGFFAQIVLP AVFVCIALMF SLIVPPFGKY PSLELQPWMY
DEQYTFVSND APEDPGTQRL LDALLNKPGF GTRCMQGHSI PDTPCTVGQT EWTTASVPDS
VLNIFLKGNW SMENPSPSCE CSNEKIKKML PVCPPGAGGL PPPQREQDTA DILQNLTGRN
ISDYLVKTYV QIIGKSLKNK VWVNEFRYGG FSLGASSSLM LPPSHEVTDA IKQVKKILEL
AQGSSGDRFL DSLSSFMKGL DTKNNVKVWF NNKGWHAXAS FLNVINNAIL RANLEQGKNP
SAYGITAFNH PLNLTKQQLS EVALMTTSVD VLVSICVIFA MSFVPASFVV FLIQERVSKA
KHLQFISGVK PVIYWLANFV WDMCNYIVPA TLVIIIFICF QQKSYVSSSN LPVLALLLFL
YGWSITPLMY PASFVFKIPS TAYVVLTSVN LFIGINSSVA TFVLELFTNN KLNNINDILK
SVFLIFPHFC LGRGLIDMVK NQAMADALER FGENRFVSPL SWDLVGRNLF AMAVEGVVFF
FITVLIQYRF FIRPRPVYAK LPPVNDEDED VTRERQRIIS GGGQSDILEI KELTKIYRMK
RKPAVDRICV GIPPGECFGL LGVNGAGKSS TFKMLTGDTD VTGGEAFLKG NSILSNIQEV
HQNMGYCPQF DAVNELLTGR EHLEFYALLR GVPEKEVCKV GEWAIRKLGL VKYGEKYAGN
YSGGNRRKLS TAIALIGGPP VVFLTLNSCA GALVYRFGDG YTIVVRIAGA NPDLKPVEEF
FGHAFPGSVL KEKHRNMLQY QLPSSPSSLA RIFSILSQNK KRLHIEDYSV SQTTLDQVFV
NFAKDQSDDD HTKDLSLHKN QTVVDIAILN SFLQDEKYAF TSTAEIVHCG IVASGYL
//
