ID A0A0Q3PM85_AMAAE Unreviewed; 648 AA.
AC A0A0Q3PM85;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=AAES_76704 {ECO:0000313|EMBL:KQK82139.1};
OS Amazona aestiva (Blue-fronted Amazon parrot).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK82139.1, ECO:0000313|Proteomes:UP000051836};
RN [1] {ECO:0000313|EMBL:KQK82139.1, ECO:0000313|Proteomes:UP000051836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FVVF132 {ECO:0000313|EMBL:KQK82139.1};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DDX59 subfamily.
CC {ECO:0000256|ARBA:ARBA00009718}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQK82139.1}.
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DR EMBL; LMAW01002002; KQK82139.1; -; Genomic_DNA.
DR STRING; 12930.A0A0Q3PM85; -.
DR Proteomes; UP000051836; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd17962; DEADc_DDX59; 1.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.30.60.220; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR InterPro; IPR007529; Znf_HIT.
DR PANTHER; PTHR47959:SF13; ATP-DEPENDENT RNA HELICASE RHLE; 1.
DR PANTHER; PTHR47959; ATP-DEPENDENT RNA HELICASE RHLE-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF04438; zf-HIT; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KQK82139.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000051836};
KW Zinc {ECO:0000256|ARBA:ARBA00022771};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 232..260
FT /note="DEAD-box RNA helicase Q"
FT /evidence="ECO:0000259|PROSITE:PS51195"
FT DOMAIN 263..434
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 445..608
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 94..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 232..260
FT /note="Q motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00552"
FT COMPBIAS 101..121
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 648 AA; 72297 MW; 076B060D4C8C7072 CRC64;
MELSIYVDAL RLTGSLLEKE GVXRSMFLPR SVKVKRTADE DRSCTAAKKN KLSSGGSLLE
ETTKFEDCKS VRTETSASRC SEVVQKHTEA VAADPGVANT ALGKDNQNND EGSSLEEPIK
SFSKSQRWAE PGEPVCVVCG RYGEYICDKT DEDVCSLECK AKHLLQTQEK ENKLKSDQLT
RAESQTEAHL PNTPYFYRDH SFILSLQDEQ VENLKLQLGI AVQGQQIPRP ILEFQHCGFP
ETLNHNLKNS GYEVPTPIQM QMIPLGLLGR DIVASADTGS GKTAAFLLPV IMKVLKETET
PSALILSPTR ELAIQIERQA KELMAGLPNM RTVLLVGGLP LPPQLHRLKQ SVKVIIATPG
RLLEILKQSS VQLHGIKIVV VDEVDTMLKM GFQQQVLDIL EDISHDHQTI LVSATIPVGI
EHLANQLLHN FVRITIGEKN LPCSNVRQII LWVEEPSKKK KLFEILNDKK LFKPPVLVFV
DCKLGADLLS DAVHKITGLQ CTAMHSEKSQ VERTDILQGL LQEKYEVIVS TGVLGRGLDL
VNVKLVVNFD MPSSMDEYVH QVGRAGRLGH SGTAITFINN NSKKLFWDVV KRVKPTGTIL
PPQLLNSPYL HDQKRREQQR LKQLENSLVT GDNIMDIIRK HDKNNSQR
//
