ID A0A0Q3RG08_SETIT Unreviewed; 417 AA.
AC A0A0Q3RG08;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Legumain prodomain domain-containing protein {ECO:0000259|Pfam:PF20985};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQK98276, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EnsemblPlants:KQK98276, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQK98276,
RC ECO:0000313|Proteomes:UP000004995};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EnsemblPlants:KQK98276}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQK98276};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase C13 family.
CC {ECO:0000256|ARBA:ARBA00009941}.
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DR EMBL; AGNK02004445; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A0Q3RG08; -.
DR STRING; 4555.A0A0Q3RG08; -.
DR EnsemblPlants; KQK98276; KQK98276; SETIT_0099462mg.
DR Gramene; KQK98276; KQK98276; SETIT_0099462mg.
DR eggNOG; KOG1348; Eukaryota.
DR InParanoid; A0A0Q3RG08; -.
DR Proteomes; UP000004995; Chromosome VII.
DR ExpressionAtlas; A0A0Q3RG08; baseline.
DR GO; GO:0000326; C:protein storage vacuole; IEA:EnsemblPlants.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IBA:GO_Central.
DR GO; GO:1990019; P:protein storage vacuole organization; IEA:EnsemblPlants.
DR GO; GO:0051603; P:proteolysis involved in protein catabolic process; IBA:GO_Central.
DR GO; GO:0006624; P:vacuolar protein processing; IBA:GO_Central.
DR CDD; cd21115; legumain_C; 1.
DR Gene3D; 1.10.132.130; -; 1.
DR Gene3D; 3.40.50.1460; -; 1.
DR InterPro; IPR043577; AE.
DR InterPro; IPR048501; Legum_prodom.
DR InterPro; IPR046427; Legumain_prodom_sf.
DR InterPro; IPR001096; Peptidase_C13.
DR PANTHER; PTHR12000; HEMOGLOBINASE FAMILY MEMBER; 1.
DR PANTHER; PTHR12000:SF25; VACUOLAR-PROCESSING ENZYME BETA-ISOZYME 1; 1.
DR Pfam; PF20985; Legum_prodom; 1.
DR Pfam; PF01650; Peptidase_C13; 1.
DR PIRSF; PIRSF500139; AE; 1.
DR PIRSF; PIRSF019663; Legumain; 1.
DR PRINTS; PR00776; HEMOGLOBNASE.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 305..400
FT /note="Legumain prodomain"
FT /evidence="ECO:0000259|Pfam:PF20985"
FT ACT_SITE 101
FT /evidence="ECO:0000256|PIRSR:PIRSR019663-1"
FT ACT_SITE 143
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR019663-1"
SQ SEQUENCE 417 AA; 46633 MW; 14B00FA1984948F9 CRC64;
ADVCHAYQIL LKGGVKEENI VVFMYDDIAH NILNPRPGVI INHPKGENVY PGVPKDYTGD
QVTTENFFAV LLGNRSAITG GSKKVIDSKP NDHIFIYYSD HGGPGVLGMP NLPYLYAGDF
IKVLKKKHAS NSYSKMVIYV EACESGSIFE GLMPQDLNIY VTTASNPVEN SWGTYCPGMD
PSPPPEYITC LGDLYSVSWM EDSQTHNLMK ETIKDQYEVV KTRTSNLKKY KEGSHVMEYG
DKTFTNEKLF LYQGFDPANA NAANTLLWPG PKGAVNQRDA DLLFMWKRYE QLDGGSEEKL
RALREIKETV QHRKHLDSSI DFIGRLVFGF ENGPKMLEAV RASGQPLVDD WDCLKRMVRI
FEAQCGSLTQ YGMKYMRAFA NICNSGISEA KMRESSISAC GGYNSARWSP MAQGHSA
//
