ID A0A0Q3UR64_AMAAE Unreviewed; 803 AA.
AC A0A0Q3UR64;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 22-FEB-2023, entry version 32.
DE SubName: Full=Ral guanine nucleotide dissociation stimulator-like 1 {ECO:0000313|EMBL:KQK76946.1};
GN ORFNames=AAES_130937 {ECO:0000313|EMBL:KQK76946.1};
OS Amazona aestiva (Blue-fronted Amazon parrot).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK76946.1, ECO:0000313|Proteomes:UP000051836};
RN [1] {ECO:0000313|EMBL:KQK76946.1, ECO:0000313|Proteomes:UP000051836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FVVF132 {ECO:0000313|EMBL:KQK76946.1};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQK76946.1}.
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DR EMBL; LMAW01002799; KQK76946.1; -; Genomic_DNA.
DR STRING; 12930.A0A0Q3UR64; -.
DR Proteomes; UP000051836; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00155; RasGEF; 1.
DR CDD; cd06224; REM; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR019804; Ras_G-nucl-exch_fac_CS.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF199; RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR-LIKE 1; 1.
DR Pfam; PF00788; RA; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR SMART; SM00314; RA; 1.
DR SMART; SM00147; RasGEF; 1.
DR SMART; SM00229; RasGEFN; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50200; RA; 1.
DR PROSITE; PS00720; RASGEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000051836}.
FT DOMAIN 100..231
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 267..524
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT DOMAIN 671..770
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 234..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 556..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 595..621
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..252
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..577
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 803 AA; 90551 MW; 29370088C95FDD94 CRC64;
MKMKMQNTGR VNNGKDVGQS TKSTIQDEGE EVEEGAVYHV TLKRVQIQQA ANKGARWLGV
KKPAKGSTDR KGLPAFEDTE KVEEDQLPPE HTVSQYETCK IRTIKAGTLE KLVENLLTAF
GDNDFTYISI FLXTYRAFAS AKEVLELLLD RYGSLETPSC EEVENENSSE SKAVVRIATA
SILRAWLNQC SEDFREPPNY PCLLKMLDYL KKNISGSDPE RRAQNLLEQL QNQEMENDNE
VHNTSSGNQC DEEEPEICSP EEFTSFQEHI VAEQLTYMDA ELFKKVVPHH CLGCIWSQRD
KEENKHVAPT IRATISQFNA VTNCVVSTIL NSKELKTQQR AKIMEKWIRI AHIFKLQMII
AKAAFLGSLG HSLGRDIMMM FEELGDIFSD HDNYLTSREL LMKEGTSKFA NLDSSVKENQ
KRTQRRLQLQ KDMGVMQGTV PYLGTFLTDL IMLDTALPDY VEGGLINFEK RRREFEVIAQ
IKLLQSACNS YCMAPDQKFI RWFRRQQHLT DNESYDLSRE VEAAADTSTT SPKSRKSMVK
RFSLLFLGSE MIAHSTPIKE QPKSTPDGSS GESTDSASVS SCEFNHCEAE DVCIGPVDTP
DTLDTPDESQ KKLSESSTSS SISYSMDASP LGVASVISAP DVLFSSDKCS NSMTPITSKE
LSPVYNQQNK DMCIIRISTE DNNGNMYKSI LHEQAEVLIA TFQLTNQDKT PAVLQRALLK
HNLESDAAED YELVQVISED KELVIPDNAN VFYAMNSHVN FDFILRKKAS VNMDLKMRSH
CSLTLPRTAR RGCWSNRLSK ITL
//
