ID A0A0Q4N053_9GAMM Unreviewed; 684 AA.
AC A0A0Q4N053;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN Name=helD {ECO:0000313|EMBL:KQN56794.1};
GN ORFNames=ASF13_06670 {ECO:0000313|EMBL:KQN56794.1};
OS Erwinia sp. Leaf53.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Erwinia.
OX NCBI_TaxID=1736225 {ECO:0000313|EMBL:KQN56794.1, ECO:0000313|Proteomes:UP000050856};
RN [1] {ECO:0000313|EMBL:KQN56794.1, ECO:0000313|Proteomes:UP000050856}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf53 {ECO:0000313|EMBL:KQN56794.1,
RC ECO:0000313|Proteomes:UP000050856};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQN56794.1, ECO:0000313|Proteomes:UP000050856}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf53 {ECO:0000313|EMBL:KQN56794.1,
RC ECO:0000313|Proteomes:UP000050856};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQN56794.1}.
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DR EMBL; LMLK01000021; KQN56794.1; -; Genomic_DNA.
DR RefSeq; WP_056236825.1; NZ_LMLK01000021.1.
DR AlphaFoldDB; A0A0Q4N053; -.
DR STRING; 1736225.ASF13_06670; -.
DR Proteomes; UP000050856; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR CDD; cd18807; SF1_C_UvrD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR022161; Helicase_IV_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF63; DNA HELICASE IV; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF12462; Helicase_IV_N; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000050856}.
FT DOMAIN 195..505
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 216..223
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 684 AA; 77566 MW; 81A820357FFC9A04 CRC64;
MELKATSLGK HLAQHPYNRV RLLNAGVEVS GEKHEYLIPF NQLLAVRCKR GLVWGELEFS
LADDKVVRLH GTEWGETQRF YHYFSQAWQQ WSEEMSGIAA GVLEAQAGRL RELEQQDRWL
KRADISSFQQ QIDDTFAALP LPVDRLADFD VCRPPYEYCL QWLQDSESQR QARNGAWTRR
MLQQYADFFD GVESSPLNDA QARAVVNGEE SVLVLAGAGS GKTSVLVARA GWLLLRKQAV
ASQILLLAFG RQAAQEMNAR ISERLHSDEI EARTFHSLAL HIIQQGSKKS PVVSRLESDT
DARHRLLIDA WRQQCSEKKA QASGWRQWLT DELEWQLDDG SFWQDDRLAK KLASRLDRWL
GLMRTHGGAQ AAMIDSAPEA VRDLFSKRIR LMAPLLKAWK NALKEEGAVD FAGLIHQAVN
ILEKGRFVSP WKHILVDEFQ DISPQRAALL SALRRQNSQT TLFAVGDDWQ AIYRFSGAEM
TLTTAFHHYF GEGDRCVLDT TYRFNQRIGE VANRFVQSNP HQLKKPLNSL TKGGAKAVQL
LPDDQLEALI NKMSGYVKSG ERVLLLARYH YLRPPLLDKA ATRWPNLTLD FMTIHASKGQ
QADYVILLGL SAGKEGFPAA ARESVMEAAL LPQAEDFPDA EERRLAYVAL TRARHQVWLM
VDRQQPSAFV AELIRQGVPQ LRKP
//
