ID A0A0Q7SRM8_9BURK Unreviewed; 518 AA.
AC A0A0Q7SRM8;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Tryptophan halogenase {ECO:0008006|Google:ProtNLM};
GN ORFNames=ASD35_01530 {ECO:0000313|EMBL:KQY90517.1};
OS Pelomonas sp. Root1444.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Roseateles.
OX NCBI_TaxID=1736464 {ECO:0000313|EMBL:KQY90517.1, ECO:0000313|Proteomes:UP000051648};
RN [1] {ECO:0000313|Proteomes:UP000051648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root1444 {ECO:0000313|Proteomes:UP000051648};
RA Garrido-Oter R., Mueller D.B.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQY90517.1, ECO:0000313|Proteomes:UP000051648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root1444 {ECO:0000313|EMBL:KQY90517.1,
RC ECO:0000313|Proteomes:UP000051648};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQY90517.1}.
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DR EMBL; LMFP01000001; KQY90517.1; -; Genomic_DNA.
DR RefSeq; WP_056873136.1; NZ_LMFP01000001.1.
DR AlphaFoldDB; A0A0Q7SRM8; -.
DR STRING; 1736464.ASD35_01530; -.
DR Proteomes; UP000051648; Unassembled WGS sequence.
DR GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR006905; Flavin_halogenase.
DR InterPro; IPR033856; Trp_halogen.
DR PANTHER; PTHR43747; FAD-BINDING PROTEIN; 1.
DR PANTHER; PTHR43747:SF4; FLAVIN-DEPENDENT TRYPTOPHAN HALOGENASE; 1.
DR Pfam; PF04820; Trp_halogenase; 1.
DR PIRSF; PIRSF011396; Trp_halogenase; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|PIRSR:PIRSR011396-2};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR011396-2};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR011396-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000051648}.
FT BINDING 12..15
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT BINDING 192
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT BINDING 351
FT /ligand="L-tryptophan"
FT /ligand_id="ChEBI:CHEBI:57912"
FT /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
SQ SEQUENCE 518 AA; 56354 MW; 3B89300BD2C2754E CRC64;
MSDIQSIVIV GGGTAGWLAA CYLQRTLGAA RQSPLPITLI EPPQAVSLGA DLATVPTLRG
TMQALGLPER ALFTAADATL SNGLRFNGWR RGGAAPDDSF DHPFDIPPPF HGFATTAHWL
NLLQRGLTRE PMAQACAVQT TLFDGHQSPK LVDSPEYQAP VSYGYQLDAV KLAMLLQQKA
LERGVRHVQG EVVRVQRGAG GIEAVELADG RRCEASFFID CTGSRSLLLQ QALGVPWVSF
ADWLPCDRTV SLPLAHGQAH GALRSHTTAT AQAAGWTWDM DLQSRRGTGY VYASRFCSED
EAVATLRELG AGHKPLAEPR LQRLRAGHAA RAWEANCLAL GAAGGFIEPL ESTGLYLVEW
MLQLFVDHVA PAGNSDACRG RVNRVFGDFY EEMRDFIVAH YALSQRRDTP FWRACTEEAT
LPPRLAELLA LWDSKVPTPT DLDRRLSLFG VANWSYLLAG LQRLPSRGIG LSDHISPEIS
LKAMAHVQGI RRIAAAQSPT MRDYLLSLDG VVTSHAAH
//
