ID A0A0Q7SZ23_9BURK Unreviewed; 394 AA.
AC A0A0Q7SZ23;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:KQY88775.1};
DE EC=2.3.1.9 {ECO:0000313|EMBL:KQY88775.1};
GN ORFNames=ASD35_14665 {ECO:0000313|EMBL:KQY88775.1};
OS Pelomonas sp. Root1444.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Roseateles.
OX NCBI_TaxID=1736464 {ECO:0000313|EMBL:KQY88775.1, ECO:0000313|Proteomes:UP000051648};
RN [1] {ECO:0000313|Proteomes:UP000051648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root1444 {ECO:0000313|Proteomes:UP000051648};
RA Garrido-Oter R., Mueller D.B.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQY88775.1, ECO:0000313|Proteomes:UP000051648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root1444 {ECO:0000313|EMBL:KQY88775.1,
RC ECO:0000313|Proteomes:UP000051648};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQY88775.1}.
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DR EMBL; LMFP01000003; KQY88775.1; -; Genomic_DNA.
DR RefSeq; WP_056873981.1; NZ_LMFP01000003.1.
DR AlphaFoldDB; A0A0Q7SZ23; -.
DR STRING; 1736464.ASD35_14665; -.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000051648; Unassembled WGS sequence.
DR GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR18919:SF153; TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:KQY88775.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000051648};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:KQY88775.1}.
FT DOMAIN 6..264
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 272..394
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 90
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 351
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 381
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 394 AA; 40665 MW; 20E8B9E763687309 CRC64;
MSQQDIVIVA AARTAIGKFG GTLAKTPASE LGAAVIQDLL RRTGLAGDQV NEVILGQVLT
AGVGQNPARQ AVIKAGLPHA VPAMTINKVC GSGLKAVMLA AQAIRDGDSD IVIAGGQESM
SLSPHVLPNS RDGQRMGDWK MVDTMISDGL WDVYNQYHMG ITAENVAKKY GITREQQDAL
ALGSQQKAAA AQDAGRFKDE IVPFTIPQKK GDPVVFAADE FINRKSNADA LAGLRPAFDK
AGSVTAGNAS GLNDGAAGVV VMTAAKAAAL GLTPLARIAS YASAGLDPAY MGMGPVPAAR
KALERAGWKP ADLDLLEINE AFAAQACAVH NEMGWDLSKV NVNGGAIALG HPIGASGCRV
LVTLLHEMVK RDAKKGIASL CIGGGMGVAL TVER
//
