ID   A0A0Q8NS32_9ACTN        Unreviewed;      1029 AA.
AC   A0A0Q8NS32;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   24-JAN-2024, entry version 44.
DE   RecName: Full=Carrier domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=ASE03_05500 {ECO:0000313|EMBL:KRB63999.1};
OS   Kitasatospora sp. Root187.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Kitasatospora.
OX   NCBI_TaxID=1736486 {ECO:0000313|EMBL:KRB63999.1, ECO:0000313|Proteomes:UP000051829};
RN   [1] {ECO:0000313|EMBL:KRB63999.1, ECO:0000313|Proteomes:UP000051829}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Root187 {ECO:0000313|EMBL:KRB63999.1,
RC   ECO:0000313|Proteomes:UP000051829};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KRB63999.1, ECO:0000313|Proteomes:UP000051829}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Root187 {ECO:0000313|EMBL:KRB63999.1,
RC   ECO:0000313|Proteomes:UP000051829};
RA   Schulze-Lefert P.;
RT   "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC         Evidence={ECO:0000256|ARBA:ARBA00001957};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRB63999.1}.
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DR   EMBL; LMHX01000034; KRB63999.1; -; Genomic_DNA.
DR   STRING; 1736486.ASE03_05500; -.
DR   Proteomes; UP000051829; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0008610; P:lipid biosynthetic process; IEA:UniProt.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.980; -; 2.
DR   Gene3D; 1.10.1200.10; ACP-like; 1.
DR   Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR   Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR001242; Condensatn.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR006162; Ppantetheine_attach_site.
DR   NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR   PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR   PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF00668; Condensation; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   SUPFAM; SSF47336; ACP-like; 1.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR   PROSITE; PS00455; AMP_BINDING; 1.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE   4: Predicted;
KW   Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051829}.
FT   DOMAIN          26..380
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          548..606
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|Pfam:PF00550"
FT   DOMAIN          626..956
FT                   /note="Condensation"
FT                   /evidence="ECO:0000259|Pfam:PF00668"
FT   REGION          141..166
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1029 AA;  106816 MW;  C030E9DAD984341A CRC64;
     MNGSLSFGPS TAIPTAATAH HAVLAVAART PDAPALRAGG RVVSYHELVE RARAVQVTLG
     QLGVRPGSFV PVLARPGEAF TVAALGVLLA GGAYAALDPQ WPAERVNGVV DDLAAAFVLD
     TTGAGLASAA VPVVALPGAA LPHGGRPHGG RPGAGAAPSA DPAPVETGAD APACVFFTSG
     STGRPKGVAV PHRAVLRSFL DGGYADLGPD TVMPLVAAPY WDAGTLETFG SLLNGGCAVE
     VPDGLLTPAG LRRLVREDGV NTLFLTSSLA NLILDEDPGA FTGVRHLMVG GERVSPSHLA
     TFLAEHPGVR LSNCYGPVES MVFATTHDVS AADLDAADGI PIGTAIRNTV LAVLNAEGGL
     APVGQVGELL IGGDGLALGY VNRPEENAKR FGVLELPGRE PLRVYRTGDL VRMTADGRLS
     YLARADRQFK VRGYRIEPGE VERVLGALDG VRECFLLPVR TADGTVTGTV CAYTAEPGPA
     LTAEELSRLS AAALPSYLRP DRFVRLDALP LGPTGKADLR AVEQLVRPVE PTGTAAPVQG
     PDGSPALRAV REILGVPWLG PDQDLLSFGA NSLQMLRIAA RLSVLLDTEF SARDVYRHST
     VVALERLAAR RPGRTASRPG RDDGQLSSGE RRFWIAEQLA PGAPGHVAMS RIEVSGPIDA
     ERLEQALAAV AAAHPALRTT FPLDRSRPHR AVAAHPALPP LLRRSGPGKS ELTSLTDELA
     ASVHDLANGP LLAAGLLTER ADRHTLLIAV HHAVYDAHSE QVLLGDLAAA WDGAALPPAS
     GPPAXXXADA ADADRAFWQA ELAGLEPLAL PVATPDLRQL WTAPVTGQPI ALPAGTAGLL
     RAAAVRHRTP ALTLLLAAWW RALSGWTGQL DLAIGTVVAD RAPADDRTIG YLANGLPIRV
     PGHPGASGPE LLALVGDRLL AAFAHAALPT DRIAALAPRP PAGRSPLYQT MLVLQRVSAP
     VRLGAAALRP RPAPPLGPQT ELCCELWEDG DELTGALHAP LGLLPPDTLA LLTGLFASEL
     NLLLTKDLT
//