ID A0A0Q9TK36_9ACTN Unreviewed; 320 AA.
AC A0A0Q9TK36;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=6-phosphogluconate dehydrogenase {ECO:0000313|EMBL:KRF34789.1};
GN ORFNames=ASG94_11515 {ECO:0000313|EMBL:KRF34789.1};
OS Nocardioides sp. Soil805.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=1736416 {ECO:0000313|EMBL:KRF34789.1, ECO:0000313|Proteomes:UP000051356};
RN [1] {ECO:0000313|EMBL:KRF34789.1, ECO:0000313|Proteomes:UP000051356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Soil805 {ECO:0000313|EMBL:KRF34789.1,
RC ECO:0000313|Proteomes:UP000051356};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KRF34789.1, ECO:0000313|Proteomes:UP000051356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Soil805 {ECO:0000313|EMBL:KRF34789.1,
RC ECO:0000313|Proteomes:UP000051356};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the HIBADH-related family.
CC {ECO:0000256|ARBA:ARBA00009080}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRF34789.1}.
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DR EMBL; LMSU01000002; KRF34789.1; -; Genomic_DNA.
DR RefSeq; WP_056926611.1; NZ_LMSU01000002.1.
DR AlphaFoldDB; A0A0Q9TK36; -.
DR STRING; 1736416.ASG94_11515; -.
DR OrthoDB; 5176214at2; -.
DR Proteomes; UP000051356; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027}.
FT DOMAIN 13..172
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 179..291
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT ACT_SITE 181
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 320 AA; 33257 MW; EB314F4C265F6F9C CRC64;
MDTTDAHTPG SLRVGWIGAG RMGSAMASRL AKAGEDVTVW NRTRAKAEAL TEVGCAVADT
IADLRGHDVV FTMVSTPADL EQVLTGPDGL LADPDHVPGC VVDCSTVSTE SSAAMRAACA
ERGVAFLASP VSGNGKVVRA GGLSLVVSGP EETYQRVAPL LDHLGKGATY VGEGELARLA
KICHNVMLGV VTQNLAEITV LAEKGGMSRA AFLEFLNKSV MGSVFTTYKS PAFVHLDYTP
TFTPILLRKD FDLGFAAAHE LDVPMPVAAA AAAAVQGTVS SGRVDEDFAI LLDQQAMLSG
LELKPEDTPV DDGLSAADEA
//
