ID A0A0Q9X585_DROMO Unreviewed; 2512 AA.
AC A0A0Q9X585;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=Uncharacterized protein, isoform F {ECO:0000313|EMBL:KRG00612.1};
GN Name=Dmoj\GI23883 {ECO:0000313|EMBL:KRG00612.1};
GN ORFNames=Dmoj_GI23883 {ECO:0000313|EMBL:KRG00612.1};
OS Drosophila mojavensis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7230 {ECO:0000313|EMBL:KRG00612.1, ECO:0000313|Proteomes:UP000009192};
RN [1] {ECO:0000313|EMBL:KRG00612.1, ECO:0000313|Proteomes:UP000009192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15081-1352.22 {ECO:0000313|Proteomes:UP000009192};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
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DR EMBL; CH933806; KRG00612.1; -; Genomic_DNA.
DR RefSeq; XP_015021718.1; XM_015166232.1.
DR SMR; A0A0Q9X585; -.
DR EnsemblMetazoa; FBtr0423247; FBpp0381208; FBgn0146608.
DR GeneID; 6572144; -.
DR OrthoDB; 2891597at2759; -.
DR Proteomes; UP000009192; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0045202; C:synapse; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006887; P:exocytosis; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR CDD; cd04031; C2A_RIM1alpha; 1.
DR CDD; cd04028; C2B_RIM1alpha; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR010911; Rab_BD.
DR InterPro; IPR039032; Rim-like.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12157:SF21; RAB3 INTERACTING MOLECULE, ISOFORM F; 1.
DR PANTHER; PTHR12157; REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN; 1.
DR Pfam; PF00168; C2; 2.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00239; C2; 2.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS50004; C2; 2.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50916; RABBD; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000009192};
KW Synapse {ECO:0000256|ARBA:ARBA00023018};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 4..130
FT /note="RabBD"
FT /evidence="ECO:0000259|PROSITE:PS50916"
FT DOMAIN 68..118
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT DOMAIN 509..598
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 823..944
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 2362..2480
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 141..279
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 293..445
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 606..643
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 676..819
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 970..1036
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1078..1197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1209..1231
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1875..1959
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2009..2070
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2129..2164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2188..2304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 19..56
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 157..176
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..268
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..384
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..445
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 733..763
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 790..810
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 972..1011
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1018..1032
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1082..1096
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1153..1194
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1908..1957
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2129..2161
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2217..2233
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2242..2279
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2512 AA; 272860 MW; 12A20F61178FC88E CRC64;
MDEMPDLSHL TPHERMQIEN VLMRQKQEEE KQNEIMRRKQ DEVVTLEMQI RQRSEQQKKA
GVELDATCHI CLKTKFADGV GHICHYCNIR CCARCGGKVT LRSNKVIWVC ILCRKKQELL
SKTGQWINKT AVQQDGFIRR IEPDGSSDIS QQAIVDPRDS ADKRPKLERT RSAAEKENLP
MQRAGSMLRR QYSQQEQPTN RRLSVSDSGM EPLSPGQQQM QQQQLPQRQR MQPMNPQQAQ
QYQLQQQQLQ QQQQQQLGYG QQQHPQRSGA YPEDDPRYYQ GELDGLMRQH PHLAHPSQVQ
QQPQQQQQQQ PQQQQPQQHL IPQQQRFNAR QQHMQQQQQQ QHQQQQQQQQ PQQQQQQRML
QQQQPYQGSS THAQIHSQPA QLGGGSGYQK APPLTRNLTI SGGHAMDATT YNQQQQQQQQ
RRSLAGAQYA SQQQRSFSSS EEEFQSHLMA AQAQAQVQGH TVTAGSDYDG NFGVVQSVQT
NLSPGDLQIH ANNPVNWQTS ADNTRMIGHM ILRKYYDGED ILGLKVNGGQ PVGLGGPCRA
IVEKVKRGSV ADVEGCIRPG DEIIEWNGRS LHNKSADEVY DIIDESRLDA QVELIVGRSL
LLPSSGAGSV DSGSSSNVSP SSACSGSGSS VTRRSSANFP HSGLASSMAA SAVVSSGGRY
LQRKAPGVEA LELHRDKPSV LITSPGSPDL HTGGSNNGLR HRGAGIGSCS QQSQRLEASS
HNHSHSHSHS HSYSSHSHSS SGSGSNSGSS SNSSATVAAS GGVHSATTAG HHHHCHPTAA
SPPSHAHALP HPHPHPHSHS HSHAHAHSHH GHGMGVTTQP IPIEGRLQLK LGYDQTTLQL
IVTLVCATGL SLRQSGAGRN PYAKVFLLPD RSQKSKRRTK TVGTTCEPRW GQTFFYSGLR
RSDLNGRQLE VTLWDYVRYG ANDFIGEVVI DLAHHVLDDE AEWYQLQPHQ DSSHLLRDEG
SDVECLILTP TDHLSPPSTM SRLSDSDTTS ECDIDGTTPG ASISSMGSSA SPPLFELDLN
ERRSRRDMSP QGRKRVAGMM ARDYRTVSGI GQSYHNQSSA TTAGYYRRGG ANGVGSAIGP
GGMSLSQRSH SAAPSDNYHG HQGHPGTGYG YRSSSPRRGS LSPPDDRYID YPVLPIHGSP
NAAAYGGGGS GASAAAQTPQ QQRFQSRSAT ATPTGSPKKR QLPQVPQTSR SAMLRDRLGQ
DFDERLASGS RFGRHRTRQP HHQATYRSTG MGGWERHYTG LSDSDLQSMD TRMRPRHSLS
PDKDFMGEFG DSDMESVVSV TSSAFSTQSE RPRTSRGLSF PRNWRNLFGA QSSILGGAVG
GPVTGLKVYP VEHHRANTIE VDDCDYLSSG GGAHQLLLLE QLEQLQQLAA LAAADSPPNT
AALGGFSGAA SAVPPPPTTI PLPMTAPQQV LVTDTNSGEL IEQFFVEPAL MAEETPLNLE
PHEPHLLTHS VYYSPHLPNT FIQPPLDLYQ RRHNGRQLDH APTIATATAT ANATTHANHT
YALPGFEQFK RYTTPVMNLF RSSTTAPPAS AHDHAHTVSS SPSSYVGYVR DHLDKSCSHC
QNGSQPVVLS TNTALATPGL AIGACTDPCC LADAHPHPQH KPIAYPYSAE QLLRRPSLSM
YQPASTSEPS LPTMDPDPMC GECVDQHFLG GLIGPQLNLG VVPTYHVHTP TATAHRRANS
QLAPPPPLPT QSVLRLSRQL SEDALVSAVP IAEATARAQP TSILKKPKLD RRRMFHEGQS
RSLDYDDLHT KSWGRRRIRY EDEVAPHELM PHAYHPSEEQ LPSSRRYGSE TNIRQSYMGA
NVDAANPLSH SHFLVTDDKI VTITYDSDVG WTRRGVAPSL FRGPHRRGVD ARNHMSLDLQ
RTSQQKLYGP AAPYMKRRRN LPHPPSAQNA HNFSPMEAIG GGVGGGGAQN SGTYNSNNHN
SSHYTNHNSH AASSVSSVSQ FHNNQQQQQQ QPQSIRQKGK EGIIAVNGLL ASASEQLTKS
SGGSGGATSA AATAAATGNI VCDGNNANNA SSSSFANPPQ QQQQQQHHGV ANQPITTTNA
SPNKRAPSSI HNTTTTTTTT TTNDANNLTH DATSTNLTQQ QQQQPPNTCT NLITNATTNT
SSIDAATTTT TTTTTITTAT TATTTATNTT TTTTTTNTNN TNEPNATTTT TNANTNANTD
ADADADAPID VIDWDAIDAM LDDDFSEYDK EKNGANEPSG AKSVDGGGGT EEKADGSLSD
TTTDRKKCGN VDQERSPKGG SGMGKKSNST SQLSATDQYQ AQYLGSSSAS GSSTSHHHIT
LPPPHPYYQR QSRGSAGSIQ RSVEVPPVPA VTRYSAGSIH SISSSEGSSF SPSLRNDGAL
NEFVDGLGPG QLVGRQVLGA PSLGDIQLSL CHQKGFLEVE VIRARGLQQK PSSKMLPAPY
VKVYLVSGKR CIDKMKTSTA RRTLDPLYQQ QLVFKQSYSG CVLQVTVWGD YGRIEKKVFM
GVAQIMLDDL NLSNIVIGWY KLFGTTSLVS CPTNIGLGSR RSSIASLDSL KL
//
