ID A0A0Q9YV86_9COXI Unreviewed; 611 AA.
AC A0A0Q9YV86;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=RasGEF domain protein {ECO:0000313|EMBL:KRG20852.1};
GN ORFNames=HT99x_02069 {ECO:0000313|EMBL:KRG20852.1};
OS Candidatus Berkiella aquae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales; Coxiellaceae;
OC Berkiella.
OX NCBI_TaxID=295108 {ECO:0000313|EMBL:KRG20852.1, ECO:0000313|Proteomes:UP000051497};
RN [1] {ECO:0000313|EMBL:KRG20852.1, ECO:0000313|Proteomes:UP000051497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HT99 {ECO:0000313|EMBL:KRG20852.1,
RC ECO:0000313|Proteomes:UP000051497};
RA Mehari Y.T., Arivett B.A., Farone A.L., Gunderson J.H., Farone M.B.;
RT "Draft Genome Sequences of Two Novel Amoeba-resistant Intranuclear
RT Bacteria, Candidatus Berkiella cookevillensis and Candidatus Berkiella
RT aquae.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRG20852.1}.
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DR EMBL; LKAJ01000008; KRG20852.1; -; Genomic_DNA.
DR RefSeq; WP_075066695.1; NZ_LKAJ02000001.1.
DR AlphaFoldDB; A0A0Q9YV86; -.
DR STRING; 295108.HT99x_02069; -.
DR Proteomes; UP000051497; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR Pfam; PF00617; RasGEF; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000051497}.
FT DOMAIN 188..413
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 570..611
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 570..592
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 593..611
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 611 AA; 69280 MW; 383A195A15B1443B CRC64;
MLSGTYKKSK SDSKIQPEPQ EQKINTAFKE CGFHPYTAVI EPVEQISDWL LQLFKSSDSP
TGMTINQNLL CEIACGIIEE ATPSSVLEIL GKIYYLLGPN EQLACLYLAK EFIHQDTHCE
WIVTNQFSDA YYHLLDKIEV TSEMKMHLKA TLIEYYKSKL PNKLIASEVD EVALLPDLKR
QSLEQKKPLK FFVSEVSGLF CQAMLSLSPE AMLTNSIMKS NDDKPAWKNI TVLSSQLSHL
VCLDILSVKD MEERARRIEF YIAAVNLLLN NKEKTPHLTP AYSIYLGICQ NPVTRLKATW
TLINEKSRAT FATFEELFQM SNGFSKVRQY IKLNPSSMPF INCIAADKDK ISFNSLGERI
FLYGKMNHDF IQLQERIGRQ KLASSQVTIG EKLKQVTYDE AAAYRQSYCY EPPIIIVLNA
NLTKDDLLNK LQRCFASKAP LVAQKGLQMC TGLLAKTVIA EFSSTMLMTN HYELLGQDNT
VSDLCGNILD QFGTESMDDM LQQLAALSLE ARTAGRKMAK RGKTKSLELK TKIPSEKSEK
KLKRRSETLK LKPIAEFEAK KESQEIVLST SNTFLPSRPT SPRAPRKIQT LETQTMGKEK
DKDKEKKRVS K
//
