ID A0A0R0AKU9_9GAMM Unreviewed; 357 AA.
AC A0A0R0AKU9;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=2-oxoisovalerate dehydrogenase {ECO:0000313|EMBL:KRG41815.1};
GN ORFNames=ARC20_11420 {ECO:0000313|EMBL:KRG41815.1};
OS Stenotrophomonas panacihumi.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Stenotrophomonas.
OX NCBI_TaxID=676599 {ECO:0000313|EMBL:KRG41815.1, ECO:0000313|Proteomes:UP000051802};
RN [1] {ECO:0000313|EMBL:KRG41815.1, ECO:0000313|Proteomes:UP000051802}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 16536 {ECO:0000313|EMBL:KRG41815.1,
RC ECO:0000313|Proteomes:UP000051802};
RA Patil P.P., Midha S., Patil P.B.;
RT "Genome sequencing and analysis of members of genus Stenotrophomonas.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRG41815.1}.
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DR EMBL; LLXU01000085; KRG41815.1; -; Genomic_DNA.
DR RefSeq; WP_057647010.1; NZ_PZOY01000001.1.
DR AlphaFoldDB; A0A0R0AKU9; -.
DR STRING; 676599.ARC20_11420; -.
DR OrthoDB; 9780894at2; -.
DR Proteomes; UP000051802; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000051802};
KW Thiamine pyrophosphate {ECO:0000256|ARBA:ARBA00023052}.
FT DOMAIN 35..210
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 357 AA; 38284 MW; 92158D3E93307160 CRC64;
MDEIKRSTAS TTASHDAAAH HAAERGTPAM TATPITLIEA VTQALAWELA HDPSVLVLGE
DVGVNGGVFR ATAGLQQKFG SERVLDTPLD ETTIAGLTVG LAAQGMKPVA EAQFDGFVYP
MVDHIICHAA RLRTRTRGRL HCPMVLRVPW GGGIRAPEHH SEANEAIFTN VPGLRVVLPS
SPQRAYGLLL AAIREPDPVI YMEPKRIYRQ YKEVVVDDGE ALPLDVCFVL RDGTDVSLVA
WGAQVKEALE AADKLAGEGI SAEVIDVATL RPLDFDTIAE SVAKTGRCVI VQEAPKTAGF
GAEIAARLAE ESMFDLVAPV QRVTGYDTHI PLFRLEMKYL PSVERIVAAA KKAVAAG
//
