ID A0A0R1GT88_9LACO Unreviewed; 218 AA.
AC A0A0R1GT88;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE RecName: Full=Probable DNA-directed RNA polymerase subunit delta {ECO:0000256|HAMAP-Rule:MF_00357};
DE AltName: Full=RNAP delta factor {ECO:0000256|HAMAP-Rule:MF_00357};
GN Name=rpoE {ECO:0000256|HAMAP-Rule:MF_00357};
GN ORFNames=FD07_GL000370 {ECO:0000313|EMBL:KRK36952.1};
OS Levilactobacillus parabrevis ATCC 53295.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Levilactobacillus.
OX NCBI_TaxID=1267003 {ECO:0000313|EMBL:KRK36952.1, ECO:0000313|Proteomes:UP000051176};
RN [1] {ECO:0000313|EMBL:KRK36952.1, ECO:0000313|Proteomes:UP000051176}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53295 {ECO:0000313|EMBL:KRK36952.1,
RC ECO:0000313|Proteomes:UP000051176};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- FUNCTION: Participates in both the initiation and recycling phases of
CC transcription. In the presence of the delta subunit, RNAP displays an
CC increased specificity of transcription, a decreased affinity for
CC nucleic acids, and an increased efficiency of RNA synthesis because of
CC enhanced recycling. {ECO:0000256|HAMAP-Rule:MF_00357}.
CC -!- SUBUNIT: RNAP is composed of a core of 2 alpha, a beta and a beta'
CC subunits. The core is associated with a delta subunit and one of
CC several sigma factors. {ECO:0000256|HAMAP-Rule:MF_00357}.
CC -!- SIMILARITY: Belongs to the RpoE family. {ECO:0000256|ARBA:ARBA00009828,
CC ECO:0000256|HAMAP-Rule:MF_00357}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRK36952.1}.
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DR EMBL; AZCZ01000014; KRK36952.1; -; Genomic_DNA.
DR RefSeq; WP_020089157.1; NZ_KB911377.1.
DR AlphaFoldDB; A0A0R1GT88; -.
DR STRING; 357278.IV61_GL000450; -.
DR PATRIC; fig|1267003.4.peg.405; -.
DR eggNOG; COG3343; Bacteria.
DR OrthoDB; 401223at2; -.
DR Proteomes; UP000051176; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.1250; RNA polymerase, subunit delta, N-terminal domain; 1.
DR HAMAP; MF_00357; RNApol_bact_RpoE; 1.
DR InterPro; IPR007759; Asxl_HARE-HTH.
DR InterPro; IPR038087; RNAP_delta_N_dom_sf.
DR InterPro; IPR029757; RpoE.
DR NCBIfam; TIGR04567; RNAP_delt_lowGC; 1.
DR Pfam; PF05066; HARE-HTH; 1.
DR PROSITE; PS51913; HTH_HARE; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|HAMAP-Rule:MF_00357};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695, ECO:0000256|HAMAP-
KW Rule:MF_00357};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00357};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|HAMAP-
KW Rule:MF_00357}.
FT DOMAIN 14..81
FT /note="HTH HARE-type"
FT /evidence="ECO:0000259|PROSITE:PS51913"
FT REGION 119..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..149
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..218
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 218 AA; 24327 MW; 5B467EBA38C7F3D1 CRC64;
MELKVFEGQN KKELSMIEVA HAILSQHGDV MAFADLANAV QAYLGDSDAE VRDRLSQFYT
DLNVDGSFIS LGDNLWGLRT WYPFESIDEA TVHAEEDEDQ PKRKKRKKVN AFLADTTDDD
DVIDYDDDDP EDDDTTTYAT DDDDDDSATG SGPDLGKLQT GLGIDDDDEE DDTEDIPDGI
EDQLSQMEAP DDDDTDNLDF SADDDEADDD DDDDEEQK
//
