ID A0A0R1H7R8_9LACO Unreviewed; 298 AA.
AC A0A0R1H7R8;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=3-5 exonuclease {ECO:0000313|EMBL:KRK39921.1};
GN ORFNames=FC07_GL002170 {ECO:0000313|EMBL:KRK39921.1};
OS Loigolactobacillus bifermentans DSM 20003.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Loigolactobacillus.
OX NCBI_TaxID=1423726 {ECO:0000313|EMBL:KRK39921.1, ECO:0000313|Proteomes:UP000051461};
RN [1] {ECO:0000313|EMBL:KRK39921.1, ECO:0000313|Proteomes:UP000051461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20003 {ECO:0000313|EMBL:KRK39921.1,
RC ECO:0000313|Proteomes:UP000051461};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRK39921.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AZDA01000032; KRK39921.1; -; Genomic_DNA.
DR RefSeq; WP_057904055.1; NZ_AZDA01000032.1.
DR AlphaFoldDB; A0A0R1H7R8; -.
DR STRING; 1423726.FC07_GL002170; -.
DR PATRIC; fig|1423726.3.peg.2254; -.
DR OrthoDB; 9776650at2; -.
DR Proteomes; UP000051461; Unassembled WGS sequence.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd09755; Cas2_I-E; 1.
DR CDD; cd06127; DEDDh; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR010152; CRISPR-assoc_prot_Cas2_sub.
DR InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR NCBIfam; TIGR01873; cas_CT1978; 1.
DR PANTHER; PTHR30231; DNA POLYMERASE III SUBUNIT EPSILON; 1.
DR PANTHER; PTHR30231:SF4; PROTEIN NEN2; 1.
DR Pfam; PF09707; Cas_Cas2CT1978; 1.
DR Pfam; PF00929; RNase_T; 1.
DR SMART; SM00479; EXOIII; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000313|EMBL:KRK39921.1};
KW Hydrolase {ECO:0000313|EMBL:KRK39921.1};
KW Nuclease {ECO:0000313|EMBL:KRK39921.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000051461}.
FT DOMAIN 130..296
FT /note="Exonuclease"
FT /evidence="ECO:0000259|SMART:SM00479"
SQ SEQUENCE 298 AA; 33540 MW; F8B39CFC2D9F4ECA CRC64;
MIVITLTKVP PSLRGDLTKW YQEIQTGVYV GNVSAKIRDA LWERIMRDIG NGQATMVYNT
NNELGYIFKT TRVDRAVVDY EGIPLMMHLK TTDKQRQPGF SNAAKFHKAK VMSHQHAQHT
TNSCAAKAQP FVAIDLETTG LDVTQDKIIA IGAAKMVHDQ YSQFYQLIKI DTKVPSDITK
LTAITSEMLE SEGILLTEAL EKLKKFIADL PIVGYNSRFD MTFLANSLRQ AGLPPLSQNT
VDLMPIVKKE NKFIDNYRLS TVLPEYEIKN KQSHHALWDA AATLELATKL IEKQSLVL
//
