ID A0A0R1HM80_9LACO Unreviewed; 171 AA.
AC A0A0R1HM80;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=YrxA {ECO:0000313|EMBL:KRK45539.1};
GN ORFNames=FC66_GL001355 {ECO:0000313|EMBL:KRK45539.1};
OS Dellaglioa algida DSM 15638.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Dellaglioa.
OX NCBI_TaxID=1423719 {ECO:0000313|EMBL:KRK45539.1, ECO:0000313|Proteomes:UP000051450};
RN [1] {ECO:0000313|EMBL:KRK45539.1, ECO:0000313|Proteomes:UP000051450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15638 {ECO:0000313|EMBL:KRK45539.1,
RC ECO:0000313|Proteomes:UP000051450};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRK45539.1}.
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DR EMBL; AZDI01000007; KRK45539.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R1HM80; -.
DR STRING; 1423719.FC66_GL001355; -.
DR PATRIC; fig|1423719.4.peg.1377; -.
DR Proteomes; UP000051450; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0036094; F:small molecule binding; IEA:InterPro.
DR Gene3D; 3.30.1340.20; 3H domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR035922; 3H_dom_sf.
DR InterPro; IPR004173; 3H_domain.
DR InterPro; IPR013196; HTH_11.
DR InterPro; IPR026043; NadR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR40068; TRANSCRIPTION REPRESSOR NIAR-RELATED; 1.
DR PANTHER; PTHR40068:SF1; TRANSCRIPTION REPRESSOR NIAR-RELATED; 1.
DR Pfam; PF02829; 3H; 1.
DR Pfam; PF08279; HTH_11; 1.
DR PIRSF; PIRSF037847; NiaR; 1.
DR SUPFAM; SSF75500; Putative transcriptional regulator TM1602, C-terminal domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PIRSR:PIRSR037847-1};
KW Nickel {ECO:0000256|PIRSR:PIRSR037847-1};
KW Reference proteome {ECO:0000313|Proteomes:UP000051450}.
FT DOMAIN 6..58
FT /note="Helix-turn-helix type 11"
FT /evidence="ECO:0000259|Pfam:PF08279"
FT DOMAIN 71..165
FT /note="3H"
FT /evidence="ECO:0000259|Pfam:PF02829"
FT BINDING 75
FT /ligand="Ni(2+)"
FT /ligand_id="ChEBI:CHEBI:49786"
FT /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
FT BINDING 83
FT /ligand="Ni(2+)"
FT /ligand_id="ChEBI:CHEBI:49786"
FT /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
FT BINDING 142
FT /ligand="Ni(2+)"
FT /ligand_id="ChEBI:CHEBI:49786"
FT /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
FT BINDING 144
FT /ligand="Ni(2+)"
FT /ligand_id="ChEBI:CHEBI:49786"
FT /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
SQ SEQUENCE 171 AA; 19292 MW; F23217743C934B55 CRC64;
MNGKDRQESI KEQLYNNANA ISANQFAQQF KVSRQTIVGD IALLRAQGEQ ILASFNGYTY
DQAPNKIIKM IVCKHRVDRV QEELELLIRN GAEVQNVTIN HEIYGELSGT LLIKTENDIN
EFMTKLNGHK GRLLSELTAG IHTHLIKVAS EESFTKIQQE LFDAGLGYQT D
//
