ID A0A0R1HSW1_9LACO Unreviewed; 371 AA.
AC A0A0R1HSW1;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase {ECO:0000313|EMBL:KRK46820.1};
GN ORFNames=FC96_GL000923 {ECO:0000313|EMBL:KRK46820.1};
OS Secundilactobacillus kimchicus JCM 15530.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Secundilactobacillus.
OX NCBI_TaxID=1302272 {ECO:0000313|EMBL:KRK46820.1, ECO:0000313|Proteomes:UP000050911};
RN [1] {ECO:0000313|EMBL:KRK46820.1, ECO:0000313|Proteomes:UP000050911}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 15530 {ECO:0000313|EMBL:KRK46820.1,
RC ECO:0000313|Proteomes:UP000050911};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRK46820.1}.
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DR EMBL; AZCX01000017; KRK46820.1; -; Genomic_DNA.
DR RefSeq; WP_056943215.1; NZ_AZCX01000017.1.
DR AlphaFoldDB; A0A0R1HSW1; -.
DR STRING; 1302272.FC96_GL000923; -.
DR PATRIC; fig|1302272.5.peg.927; -.
DR OrthoDB; 6430685at2; -.
DR Proteomes; UP000050911; Unassembled WGS sequence.
DR GO; GO:0003871; F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd03311; CIMS_C_terminal_like; 1.
DR Gene3D; 3.20.20.210; -; 1.
DR InterPro; IPR002629; Met_Synth_C/arc.
DR InterPro; IPR038071; UROD/MetE-like_sf.
DR PANTHER; PTHR43844; METHIONINE SYNTHASE; 1.
DR PANTHER; PTHR43844:SF1; METHIONINE SYNTHASE; 1.
DR Pfam; PF01717; Meth_synt_2; 1.
DR SUPFAM; SSF51726; UROD/MetE-like; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:KRK46820.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000050911};
KW Transferase {ECO:0000313|EMBL:KRK46820.1}.
FT DOMAIN 168..344
FT /note="Cobalamin-independent methionine synthase MetE C-
FT terminal/archaeal"
FT /evidence="ECO:0000259|Pfam:PF01717"
SQ SEQUENCE 371 AA; 41948 MW; 72F42C62F20D06B3 CRC64;
MTIQTQTKFP NRFDIVGSFL RPDRLKQANA DFSAHKISKD DLLQVQHEEI KRIVDKQVAL
GLKDVTDGEF NRSWWHLDFL AGLKGAHFFE PDHGFIFNGQ ETRKGGIEIT EKVTFNPDHP
FFDGFKYLQS IVPDGITPKQ TIPSPSVLFP NEDAEIYDKY YNHDFEAFLA DEITAYQNTV
QRFYDLGCRY LQLDDTSWGM WASFSDKVIN PDLKPLCEAA VKAINAIVDN KPDDLTITMH
VCRGNYDSNW AGAGAYDPVA DYLAQLHIDG YFLEYDDERS GGFEPLAKIA ANGRNQRIVL
GLVTTKKPDL EAPELLKKRI ALASQYVPLA SLCLSPQCGF ASTEEGNHLT EDDQWAKLKL
VIDTAKSVWP E
//
