ID A0A0R1I042_9LACO Unreviewed; 1121 AA.
AC A0A0R1I042;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Nitrate reductase, alpha subunit {ECO:0000313|EMBL:KRK49186.1};
GN ORFNames=FC96_GL000107 {ECO:0000313|EMBL:KRK49186.1};
OS Secundilactobacillus kimchicus JCM 15530.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Secundilactobacillus.
OX NCBI_TaxID=1302272 {ECO:0000313|EMBL:KRK49186.1, ECO:0000313|Proteomes:UP000050911};
RN [1] {ECO:0000313|EMBL:KRK49186.1, ECO:0000313|Proteomes:UP000050911}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 15530 {ECO:0000313|EMBL:KRK49186.1,
RC ECO:0000313|Proteomes:UP000050911};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004202};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRK49186.1}.
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DR EMBL; AZCX01000001; KRK49186.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R1I042; -.
DR STRING; 1302272.FC96_GL000107; -.
DR PATRIC; fig|1302272.5.peg.104; -.
DR Proteomes; UP000050911; Unassembled WGS sequence.
DR GO; GO:0009325; C:nitrate reductase complex; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0008940; F:nitrate reductase activity; IEA:InterPro.
DR GO; GO:0042126; P:nitrate metabolic process; IEA:InterPro.
DR CDD; cd02776; MopB_CT_Nitrate-R-NarG-like; 1.
DR Gene3D; 3.40.50.12440; -; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR037943; MopB_CT_Nitrate-R-NarG-like.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006655; Mopterin_OxRdtase_prok_CS.
DR InterPro; IPR006468; NarG.
DR NCBIfam; TIGR01580; narG; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR PANTHER; PTHR43105:SF2; RESPIRATORY NITRATE REDUCTASE 2 ALPHA CHAIN; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS00932; MOLYBDOPTERIN_PROK_3; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000050911}.
FT DOMAIN 2..716
FT /note="Molybdopterin oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00384"
FT DOMAIN 972..1084
FT /note="Molybdopterin dinucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF01568"
SQ SEQUENCE 1121 AA; 126309 MW; 81DAD9C30069C92D CRC64;
MRIKYPYIRG KLWQLWDAAK KQYESPVEAW ASIVEDPEKA AIYKSARGHG GMVRVHRAEA
LELISAMLLY TIKTYGPDRL AGFTPIPAMS MMSYASGARF ISLLGGEMLS FYDWYADLPP
ASPQIWGEQT DVPESADWYN SQYIMMWGSN VPLTRTPDAH FMTEARYHGA KIVAVSPDYA
ENVKFADNWL APKPGTDAAL AQGMTHVILN EFYQERHEQQ FIDYVKQYTD LPFLITLQPS
DANPEDFASG RFVRITDIAA DAVENGEWKP VLFDGNQGKF VVPNGTIGQR WEDGQPWNLE
MKDQNGAEID PDLSIDADVD VTIDFPTFDN QGNGVLKRHV PAKKMTFMDG SEHYVTTVFD
LMMSQYGIKR EADDSLAATG YDDVQSCYTP AWQETVTGVK ASLVVQVARE FAQNALDTGG
KTMVIMGAGI NHWFNSDMTY RSIINNLMLC GCEGVSGGGW AHYVGQEKLR PQEGWSTIAF
ANDWQKGGAR QQNGTSFFYF ASDQWKYDEL DNKALKSPVT KTKHVYDHAA DYNQLAIRLG
WLPSYPQFDR SSLSFTDKYH TTDLGEISKH VVAELKAGDL HFAAENPDAN QNQPKGLFIW
RSNLFTSSGK GQEYFMKHLL GAENGLLAKT NDRQKPEEMI WNDETITGKL DLVIDMDFRM
VATPMYSDVI LPAATWYEKE DLSSTDMHPY IHPFNAAVSP MWESKSDWQQ FKALAKTVSN
MAKKYYAEPQ YDLKTQPLGH DSKAEIAQPM GVIKDWKKGE IDCTPGQTMP SLSLIKRDYT
QVYDKFIALG PNARGKVGGE GYTYDVSTEY DELKDILGTF DRGLNEGCPK LDVDKNVCDA
ILHLSSTSNG HVAAKAWQNA ETITGQKLQD ISAGRREDQM SFKSITVQPA EAIPTPIFTS
AKHDGDRYSP FTVNIERKVP FRTLTGRQQF YLDHEIFQEY GETLANYKPT LPPQVMGPAD
VAITPDSNEL TLRYMTPHGK WNIHTMYYDN LEMLTLFRGG PNVWLSPVDA DKAGIKDNDW
LEIYNRNGVV TARAVVSHRM PEGSMYMYHA QDMQIQEPLS TITGNRGGSH NAPTQIHVKP
TQMVGGYGQL SYAFNYYGPI GNQRDLYVNV RKLKKVNWNE D
//
