ID A0A0R1M851_9LACO Unreviewed; 538 AA.
AC A0A0R1M851;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Beta-xylosidase {ECO:0000313|EMBL:KRK99815.1};
GN ORFNames=FD04_GL002176 {ECO:0000313|EMBL:KRK99815.1};
OS Secundilactobacillus odoratitofui DSM 19909 = JCM 15043.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Secundilactobacillus.
OX NCBI_TaxID=1423776 {ECO:0000313|EMBL:KRK99815.1, ECO:0000313|Proteomes:UP000051160};
RN [1] {ECO:0000313|EMBL:KRK99815.1, ECO:0000313|Proteomes:UP000051160}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19909 {ECO:0000313|EMBL:KRK99815.1,
RC ECO:0000313|Proteomes:UP000051160};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865, ECO:0000256|RuleBase:RU361187}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRK99815.1}.
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DR EMBL; AZEE01000002; KRK99815.1; -; Genomic_DNA.
DR RefSeq; WP_054702585.1; NZ_BBFJ01000014.1.
DR AlphaFoldDB; A0A0R1M851; -.
DR STRING; 1423776.FD04_GL002176; -.
DR PATRIC; fig|1423776.4.peg.2203; -.
DR OrthoDB; 9801455at2; -.
DR Proteomes; UP000051160; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd09000; GH43_SXA-like; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR041542; GH43_C2.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR42812; BETA-XYLOSIDASE; 1.
DR PANTHER; PTHR42812:SF12; BETA-XYLOSIDASE-RELATED; 1.
DR Pfam; PF17851; GH43_C2; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361187};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361187}.
FT DOMAIN 335..536
FT /note="Beta-xylosidase C-terminal Concanavalin A-like"
FT /evidence="ECO:0000259|Pfam:PF17851"
FT ACT_SITE 14
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT ACT_SITE 187
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT SITE 127
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 538 AA; 60885 MW; C86F6BCFC0CEF55E CRC64;
MKIQNPVLHG FNADPSMIRV GDTYYIANST FEWFPGVRLH ESKDMVHWNL LPSPLSTTTL
LDMKGNPASG GIWAPDLTYA DGKFWLIYTD VKITEGAFKD MTNYLTTATD IRGPWTDPIR
VNGVGFDASL FHDDNGRKYL VQQTWDHREY HHPFNGITLT EFDTDIMKLR PETARNIYNG
TKVKLVEGPH LYKINGYYYL FAAQGGTVYT HQEVVARSKS LDELSFESEP DGPFLTNFDT
PDLGIQKQGH GALVDTPGGE WYYASLCGRP WNHENESAYD PRGWCTLGRE TSIQKVEWDD
QGWPRIVGGH GGTVEVEAPK DAILTDAPVD GSQHDEFDTP ELNGEWNTLR TPFTAEVGST
GDGKLTLIGK NSLASNFDVS MIARRWQAFD FDAETKVKFD PFTYQQMAGL TNFYNDKHWS
FIFITWDEKK GHVIEIGENN NGNYTSYLKD DAIAIPDGTE NVWFKVKARK QSYSYEYSFD
GQNWHEIPVT LDAAILSDDY VLQNYGGFFT GAFVGLAAVD YAGYDQPAEF GYFDYKEL
//
